Filtyp
Sex chromosomes have evolved from the same autosomes multiple times across vertebrates, suggesting that selection for recombination suppression has acted repeatedly and independently on certain genetic backgrounds. Here, we perform comparative genomics of a bird clade (larks and their sister lineage; Alaudidae and Panuridae) where multiple autosome-sex chromosome fusions appear to have formed expa
Simulations of a regional (approx. 50 km resolution) circulation model REMOiso with embedded stable water isotope module covering the period 1958-2001 are compared with the two instrumental climate and four isotope series (δ18O) from western Svalbard. We examine the data from ice cores drilled on Svalbard ice caps in 1997 (Lomonosovfonna, 1250 m asl) and 2005 (Holtedahlfonna, 1150 m asl) and the G
This study investigated the presence of MPs in three species of bivalves cultivated in Brazil: Crassostrea gigas, Perna perna, and Nodipecten nodosus. Our hypothesis was that the different structures and plastic materials used in the cultivation of these bivalves could serve as a contributing source of MPs. Our results showed the presence of MPs in all species, with C. gigas showing the highest le
BACKGROUND: Recent advancements in Alzheimer's disease (AD) biomarker research and clinical trials prompt reflection on the value and consequently appropriate use of tau positron emission tomography (tau-PET) in the future. METHODS: We conducted an online survey among dementia and PET experts worldwide to investigate the anticipated future role of tau-PET in clinical practice and trials. RESULTS:
Peritoneal dialysis (PD) is a kidney replacement therapy for patients with end-stage renal disease. It is becoming more popular as a result of a rising interest in home dialysis. Its effectiveness depends on several physiological and technical factors, which have led to the development of various computational models to better understand and predict PD outcomes. In this review, we traced the evolu
Plesiosaurs are an iconic group of Mesozoic marine reptiles with an evolutionary history spanning over 140 million years (Ma).1 Their skeletal remains have been discovered worldwide; however, accompanying fossilized soft tissues are exceptionally rare.2 Here, we report a virtually complete plesiosaur from the Lower Jurassic (∼183 Ma)3 Posidonia Shale of Germany that preserves skin traces from arou
INTRODUCTION: Hospital-acquired bloodstream infections (HA-BSIs) are severe and require antibiotic therapy. In non-complicated BSIs, shortened therapy reduces side effects without compromising efficacy. The impact of shortened antibiotic therapy in HA-BSI critically ill patients without indication of prolonged therapy requires further evaluation. METHODS: Using the international prospective EUROBA
Global climate change is characterized by increasing and differentiated exposure to climate-related hazards such as floods, landslides, avalanches, storms, and wildfires (IPCC 2018, 2022). There is a significant volume of research on the effects of such events, and over the last decade, much of this research has been directed at where most lives and values can be saved by protective measures (e.g.
This paper reports results of a production experiment in which nine native speakers of Tokyo Japanese read aloud sentences with varied syntactic structures, word orders, and levels of awareness of the syntactic structure. In particular, this study investigates the prosodic realization of embedded clause boundaries and potential effects of word order and readers’ awareness of the syntactic structur
Current syntheses of CsPbBr3 halide perovskite nanocrystals (NCs) rely on overstoichiometric amounts of Pb2+ precursors, resulting in unreacted lead ions at the end of the process. In our synthesis scheme of CsPbBr3 NCs, we replaced excess Pb2+ with different exogenous metal cations (M) and investigated their effect on the synthesis products. These cations can be divided into two groups: group 1 d
Retention in prevention of mother-to-child transmission (PMTCT) care is critical to prevent vertical HIV transmission and reduce morbidity and mortality of mother-infant pairs. We investigated whether weekly, interactive text-messaging improved 18-month postpartum retention in PMTCT care. This randomised, two-armed, parallel trial was conducted at six PMTCT clinics in western Kenya. Pregnant womenRetention in prevention of mother-to-child transmission (PMTCT) care is critical to prevent vertical HIV transmission and reduce morbidity and mortality of mother-infant pairs. We investigated whether weekly, interactive text-messaging improved 18-month postpartum retention in PMTCT care. This randomised, two-armed, parallel trial was conducted at six PMTCT clinics in western Kenya. Pregnant women
In microbiological studies, a common goal is to link environmental factors to microbial activities. Both environmental factors and microbial activities are typically derived from bulk samples. It is becoming increasingly clear that such bulk environmental parameters poorly represent the microscale environments microorganisms experience. Using infrared (IR) microspectroscopy, the spatial distributi
Multi-stimulus responsive poly(2-(2-methoxyethoxy)ethyl methacrylate-co-2-(diethylamino)ethyl methacrylate) [P(MEO2MA-co-DEA)] 80:20 mol % copolymer brushes were synthesized on planar silica substrates via surface-initiated activators continuously regenerated via electron transfer atom transfer radical polymerization. Brush thickness was sensitive to changes in pH and temperature as monitored with
BACKGROUND: The management of febrile infants aged ≤ 60 days and adherence to guidelines vary greatly. Our objective was to describe the process of decision-making when managing febrile infants aged ≤ 60 days and to describe the factors that influenced this decision.METHODS: We conducted 6 focus group discussions with 19 clinically active physicians in the pediatric emergency departments of 2 univ
Transformative change toward sustainability is increasingly recognized as inevitable to avoid the collapse of socio-ecological systems. However, for a deep and system-wide transformation, governance approaches and policymaking need to be changed too. This paper discusses how a diverse value approach in environmental policymaking could be undertaken to foster transformative governance that can furt
BackgroundThe global distribution of HIV-1 subtypes is evolving, which is reflected in the Swedish HIV cohort. The subtype HIV-1A6, which may be prone to developing resistance to cabotegravir, is the most common subtype in Ukraine.AimWe aimed to examine trends in HIV-1 subtype distribution in Sweden, with a special focus on HIV-1A6, and to describe the virology, demography and treatment of Ukraini
