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Biochar from cookstoves reduces greenhouse gas emissions from smallholder farms in Africa

Biochar produced in cookstoves has the potential to contribute to negative carbon emissions through sequestration of biomass carbon while also providing other benefits for sustainable development, including provision of clean renewable energy and increased yields in tropical agriculture. The aim of the reported research was to estimate effects on food production, household energy access and life c

Bioprospecting Microbial Diversity for Lignin Valorization : Dry and Wet Screening Methods

Lignin is an abundant cell wall component, and it has been used mainly for generating steam and electricity. Nevertheless, lignin valorization, i.e. the conversion of lignin into high value-added fuels, chemicals, or materials, is crucial for the full implementation of cost-effective lignocellulosic biorefineries. From this perspective, rapid screening methods are crucial for time- and resource-ef

Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives

The isoxazol leflunomide (N-(4-trifluoromethylphenyl)-5-methylisoxazol-4-carboxamide) and its active metabolite A77-1726 (N-(4-trifluoromethyl)-phenyl-2-cyano-3-hydroxy-crotonic acidamide) are promising disease-modifying antirheumatic drugs now in clinical trials. The malononitrilamides MNA279 (2-cyano-3-cyclopropyl-3-oxo-(4-cyanophenyl)propionamide) MNA715(N-(4-trifluoromethyl)-phenyl-2-cyano-3-h

Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation

The formation of amyloid deposits in human tissues is a defining feature of more than 50 medical disorders, including Alzheimer’s disease. Strong genetic and histological evidence links these conditions to the process of protein aggregation, yet it has remained challenging to identify a definitive connection between aggregation and pathogenicity. Using time-resolved fluorescence microscopy of indi

Serotonergic perturbations in dystonia disorders-a systematic review

Dystonia is a hyperkinetic movement disorder characterized by sustained or intermittent muscle contractions. Emerging data describe high prevalences of non-motor symptoms, including psychiatric co-morbidity, as part of the phenotype of dystonia. Basal ganglia serotonin and serotonin-dopamine interactions gain attention, as imbalances are known to be involved in extrapyramidal movement and psychiat

Borrowability, inheritance, and semantic change in the Indo-European and Caucasian vocabulary for hunting, farming, and technology

Vocabulary for subsistence and technology may vary a great deal in their degree of borrowability, depending on time, place, inherent subsistence and technology, and the situation of the borrowing. In cross-linguistic typological studies of borrowability, these words tend to group somewhere from middle to high in borrowability, depending on lexical concept (Haspelmath & Tadmor, 2009).We have co

A framework for Higgs characterisation

We introduce a framework, based on an effective field theory approach, that allows one to perform characterisation studies of the boson recently discovered at the LHC, for all the relevant channels and in a consistent, systematic and accurate way. The production and decay of such a boson with various spin and parity assignments can be simulated by means of multi-parton, tree-level matrix elements

Social and spatial effects on genetic variation between foraging flocks in a wild bird population

Social interactions are rarely random. In some instances, animals exhibit homophily or heterophily, the tendency to interact with similar or dissimilar conspecifics, respectively. Genetic homophily and heterophily influence the evolutionary dynamics of populations, because they potentially affect sexual and social selection. Here, we investigate the link between social interactions and allele freq

Streptococcus suis DNase SsnA contributes to degradation of neutrophil extracellular traps (NETs) and evasion of NET-mediated antimicrobial activity

Streptococcus suis is an important cause of different pathologies in pigs and humans, most importantly fibrinosuppurative meningitis. Tissue infected with this pathogen is substantially infiltrated with neutrophils, but the function of neutrophil extracellular traps (NETs) - a more recently discovered antimicrobial strategy of neutrophils - in host defence against Strep. suis has not been investig

Movements in the dark : flying, landing and walking in insects

Att färdas i mörker: insekters lösningar, vinster och kostnaderIn sin ständiga jakt på mat måste många insekter undvika att krocka med grenar, stenar och blad, samt färdas i en lämplig kompassriktning. Åtskilliga insekter använder sin syn för att kontrollera detta. En nektarsökande humla, till exempel, reglerar sin flyghastighet efter hur snabbt föremål i omgivningen rör sig över dess ögon. Denna Flying, as well as walking insects rely on vision to regulate locomotion, even in the dark when the visual system is much less reliable. To manage visual control of these behaviours at low light intensities, many insects have evolved optical adaptations, such as larger facet lenses and wider rhabdoms, and neural adaptations, such as spatial and temporal summation, to increase their visual sensitiv

Mer eller mindre byråkratisk : En studie av organisationsförändringar inom Kronofogdemyndigheten

Extensive changes in public organizations have been carried through since the end of the 20th century as a way of achieving higher efficiency. Inspiration came from the private sector. The Swedish Enforcement Authority carried through several organizational changes during this time. The authority was during 1997-2006 organized in ten independent authorities subordinated to the National Tax Board.

The void : Urban wasteland as political space

The rugged field and group of trees between housing estates or next to the railroad tracks, the left-over space of deserted industrial areas, the vacant demolition site of a central city block – they could all be termed ‘urban voids’. However, they are often anything but voids, in a literal sense, as they are not empty, or deserted. Yet they are ‘urban voids’, lacking an evident function, or a def

A model inter-comparison study to examine limiting factors in modelling Australian tropical savannas

The savanna ecosystem is one of the most dominant and complex terrestrial biomes, deriving from a distinct vegetative surface comprised of co-dominant tree and grass populations. While these two vegetation types co-exist functionally, demographically they are not static but are dynamically changing in response to environmental forces such as annual fire events and rainfall variability. Modelling s

HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5

We previously reported that the human HER2 gene encodes the intronic microRNA mir-4728, which is overexpressed together with its oncogenic host gene and may act independently of the HER2 receptor. More recently, we also reported that the oncogenic miR-21-5p is regulated by 3′ tailing and trimming by the non-canonical poly(A) polymerase PAPD5 and the ribonuclease PARN. Here we demonstrate a dual fu