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Popular Abstract in English In the age where there is a great demand of energy, raise in the prices of fossil fuels and increase of environmental concerns because of the greenhouse gas emissions, biogas production through anaerobic digestion, of different organic materials, provides a full or partial solution. There is a large number of cheap substrates as organic waste materials that can be utiliThe anaerobic digestion process results in the production of biogas from a large diversity of organic residues, which can be used as an alternate source of energy generation and for waste management. However, the biogas production technology is not exploited efficiently due to the characteristics of raw materials, poor methane yields, process instability, limited raw materials and lack of knowledg
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The retina is a thin tissue layer on the inside of the eye and may be subject to tractional forces in diseases like myopia, retinoschisis, and retinal detachment. Müller glial cells (MGCs) are the only cells spanning the entire retinal thickness and hypothetically respond to mechanical stress imposed across retinal layers. We designed a device to apply force in vitro perpendicular to the retinal s
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Both decades of the 21st century have been categorized as testing the EU constitutional foundations in the course of different crises, that have been challenging the viability of the European integration and causing alterations to EU constitutional design. The rhetoric of crisis/emergency in the EU has been consistently deployed in the areas of public security, environmental protection, migration
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During recent years new threats have accentuated the role of scientific experts for creating risk awareness, understanding, and advice for action or preparedness for informed risk decisions. Scientific experts are expected to engage in risk communication with stakeholders at various levels, not least the general public. Scientific experts exist in organizations where forms and goals may vary, as w
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Misfolding, self-assembly, and subsequent deposition of amyloid β plaques and tau tangles are closely associated with Alzheimer’s disease (AD) and its neurodegenerative processes, driving healthy neurons into a diseased state. At present, AD is the most widespread form of dementia, causing profound personal and familial hardship as well as imposing a substantial societal economic burden.Currently,The purpose of the work that forms the basis of this thesis has been to investigate fundamental properties of amyloid β and tau self-assembly and their solubility. The results of this research are presented as five research articles. In Paper I, a solubility assay for determining the solubility of amyloid proteins is developed and its use demonstrated for the Aβ40 peptide. Paper II finds that tau
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Metastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecu
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The research work that I describe in my thesis deals with three different heterogenisation approaches for synthesising a heterogeneous transition metal catalyst used for direct C-H activation reactions. The three heterogenisation approaches considered in my research are: (1) heterogenisation of a molecular catalyst on a polymer support using covalent bonds, (2) heterogenisation of a catalyst on a
