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Aims To investigate the causal role of high-density lipoprotein cholesterol (HDL-C) and triglycerides in coronary heart disease (CHD) using multiple instrumental variables for Mendelian randomization. Methods and results We developed weighted allele scores based on single nucleotide polymorphisms (SNPs) with established associations with HDL-C, triglycerides, and low-density lipoprotein cholestero

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Popular Abstract in Swedish Glas kan användas för retrospektiva radon mätningar på grund av radondöttrars förmåga att implantera i glasets översta skikt. Mängden implanterad aktivitet blir lätt påverkad av en rad olika faktorer i den omgivande luften. Experimentella metoder har därför utvecklats för att bestämma djupfördelningen av alfarekyl-implanterat 210Po i glas. Detta göres genom gradvis etsnGlass sheets are often used in radon surveys to estimate retrospective radon concentrations, as radon progenies are embedded in the upper surface layer. The implanted activity is influenced by a variety of different environmental conditions. In this work, experimental methods based on etching to determine the depth distribution of recoil-implanted 210Po in glass from radon decay in air were develo

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Cell lines derived from human squamous cell (EPCL), large cell (LCLC), and small cell lung cancer (SCLC) lines were investigated for the expression of cathepsin B (Cat B) and cysteine proteinase inhibitors (CPIs). The EPLC and LCLC lines expressed 5- to 50-fold more Cat B activity and contained more mature Cat B of M(r) 27-29 kDa (> 2.5 microg/mg total protein) than the SCLC lines (< 1.0 microg/mg

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Popular Abstract in Swedish Strålbensfrakturer i armbågsleden I denna avhandling har jag försökt kartlägga hur det går för individer som drabbats av ett benbrott i anslutning till armbågen. I underarmen finns två ben, strålbenet och armbågsbenet. Strålbenets övre del ledar dels mot överarmsbenet men också mot armbågsbenet. När en person ramlar med utsträckt arm finns det risk att det uppstår ett All elbow fractures between 1969 – 1979 (n=2965) registered at the radiographic archives at the Malmö University Hospital, where all radiographs are saved since a century, were evaluated. Fractures of the radial head and neck were classified according to the by Broberg and Morrey modified Mason classification. A Mason type I fracture is a less than 2 mm displaced fracture of the radial head or nec

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I denna bok utforskas den rättsliga hanteringen av duellbrott som ärekränkningar och dueller med dödlig utgång under stormaktsväldets slutskede. Med inspiration från New Cultural History och teorier om manlighet och våld analyseras lagtexter, rättsfall, prästers och rättslärdas skrifter samt anklagade duellanters brev och nådeansökningar. Studien fokuserar på hur den rättsliga diskursen kring duelThis dissertation examines duelling crimes in Sweden during the first half of the 18th century. During this period such crimes could involve verbal insults concerning honour as well as duelling, resulting in death. Inspired by the methods and perspectives of New Cultural History and by theories of masculinity the study argues that masculine violence is a cultural category that is historically deve

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The identification and classification of bacteria was initially performed with morphological methods applied on cultivated bacteria. It was not until the mid 1970s, when sequences of ribosomal RNA were discovered to be useful for bacterial evolution, that a new era started. This method showed to be far more accurate for bacterial identification. Today, identification of bacteria is totally dominat

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Popular Abstract in English Nowadays, the majority of energy production comes from combustion which is universally linked to daily human activities. Public awakening of the environmental effects of combustion pollution evokes extensive research activities in improving combustion efficiency and reducing pollutant production. Development of combustion processes also includes the use of renewable bioThe work presented in the thesis concerns the developments of laser-based diagnostics and its application to the study of turbulent premixed combustion. The diagnostic developments, mainly concerned with planar laser-induced fluorescence (PLIF), are intended to provide instantaneous visualization of the key species originating from the combustion processes involved in the burning of hydrocarbons

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The aim of this study is to investigate how Swedish learners of English (at different levels of proficiency) master idiomaticity in their target language. I argue that idiomaticity can be related to the storage and use of multi-word expressions that are preferred by native speakers. These multi-word units are referred to as prefabs in the present study. By manually identifying and subsequently cla

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Today, digital circuits are part of every ones daily life in form of mobile phones, computers, television, smart cards etc. The advent of new technologies such as internet of things, 5G etc. are continuously making the digital circuits more and more complex in design. With this increase in complexity comes the possibility of more bugs in the system. Finding and fixing these bugs is of paramount im

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Natural selection and genetic drift are relentlessly removing variation in natural populations. Yet, many species show polymorphism, with multiple phenotypes coexisting in the same populations, and these species serve as important model systems for studies aimed at understanding what evolutionary forces that maintain variation in natural populations. For example, different morphs can be favored in

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Gräsrotsfinansiering är en finansieringsform som växer i omfattning och popularitet. Kortfattat handlar det om att bolag söker kapital från den stora massan istället för de mer traditionella källorna. Det finns flera varianter av gräsrotsfinansiering, den som vållar de största juridiska spörsmålen är den delägarbaserade varianten. Denna innebär att investerare erbjuds aktier eller andra värdepappeCrowdfunding is a form of financing that grows in scope and popularity. In short, it is about companies seeking capital from the crowd instead of the more traditional sources. There are several different forms of crowdfunding. The one who mainly causes the legal questions is the equity form. This means that companies offer shares or other securities in, usually private, limited liability companies

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This thesis investigates the importance of scale for power dynamics in the negotiation of risks connect-ed to Urban Rivers in Nairobi, Kenya. In addition to unequal distribution of wealth, global inequalities in the distribution of risk become increasingly important. Scale as a significant dimension of inequality is discussed in the context of Nairobi’s urban, as water scarcity and flooding events

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The principle of the persistent objector strikes at the heart of international law creating uncertainty over issues as how customary international law is created, whom it binds and how states actively can evade being bound by certain customary international laws. The mere existence of this principle gives rise to a great number of diverging interpretations. The study presented herein analyses the

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Sweden is a member of the European Union since 1995. The European Union issues directives that cover different areas. Member states must implement these directives into their national legislation. The European council issued in 1993 a directive that took action on the organization of working time, also known as the working time directive. The full name is: Council directive 93/104/EC of 23 Novembe

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Purpose of the master thesis is to develop an algorithmic trading model for a single asset, which is well functioning on the Scandinavian market. Deliverables: The main focus has been towards creating an indicating model to quantify market impact, cost of trading and model an efficient trading frontier. Methodology: Initially we focused on research papers and literature within our specific field t

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Abstract This report is written in cooperation with Arjo Hospital Equipment AB. The purpose of it is to propose and suggest ways to improve the flow of information between Arjo and its suppliers. There are many aspects to this problem and Arjo constantly works with issues concerning this through evaluations and assessments. These circumstances are the actual background for this master thesis. As a

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Behovet av effektiviseringar för lagföringen av personer som har begått brott har länge diskuterats framförallt ur ett effektiviserings perspektiv men även ur ett processekonomiskt perspektiv. Stora och komplicerade mål skapar långa och resurskrävande utredningar som dessutom låter den misstänkte sväva i ovisshet under en lång tid. Ett förslag som har diskuterats men som än så länge avskrivits äThe need to make the process in which persons who have committed crimes are brought to justice has long been discussed from a efficiency perspective but also from a process economical perspective. Large and complicated cases create long and costly investigations and also make the suspects linger in uncertainty for a long time. One alternative that has been discussed but so far discarded is the i

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Sammanfattning: Ett informationssystem är i grund och botten ett sätt att lagra och bearbeta information. Alla sådana system bygger på en informationsmodell, det vill säga en modell för hur data organiseras för att de ska gå att bearbeta och omvandla till information. Idag existerar avancerade informationssystem för att göra spatiala analyser (GIS) och för att hantera byggnader (BLM-system). För nSummary: An information system is basically a way to store and process information. All such systems are built from an information model, in essence a model for how to organize data in order to make it possible to process, thus turning it into information. Today there exist advanced information systems for performing spatial analysis (GIS) and to model buildings (BLM-systems). At present the devel

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Vid företagsöverlåtelser är det inte ovanligt att parterna avtalar om en tilläggsköpeskilling. Detta innebär att säljaren erhåller en del av ersättningen för aktierna vid tillträdet och en del vid ett eller flera tillfällen efter att företaget har skiftat ägare. Tilläggköpeskillingen är normalt beroende av att det företag som är föremål för affären uppnår vissa finansiella eller andra mål efter ägIn conjunction with business sales, earn-out agreements are commonly used. An earn-out is a mechanism whereby a portion of the purchase price is contingent, and is calculated based on the performance of the acquired business over a specified period following the closing. An earn-out can also be paid to the seller on condition that he will continue his employment within the business for an agreed t

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Uppsatsen behandlar konkursboets ansvar för miljöfordringar. Uppsatsen belyser såväl konkursboets ansvar för miljöfordringar som den gränsdragningsproblematiken detta medför gällande boets ansvar för gäldenärens görande. Det finns typfall för vilka konkursboet anses bära ansvar. Dessa benämns förvarings- och verksamhetsfallen och redogör för de situationer som konkursboet får stå kostnaderna för mThis paper addresses the bankruptcy estate's responsibility for environmental claims. It highlights both the bankruptcy estate's responsibility for environmental claims and the problem this entails regarding the estate's responsibility for the debtor's actions. There are typical cases for which the bankruptcy estate is considered to bear responsibility. These are referred to as sto