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The tumor suppressor CYLD and the proto-oncogene BCL-3 are known to be deregulated in various cancer types. The molecular background of how these genes participate in carcinogenesis is not fully understood. CYLD is a deubiquitinating enzyme known to specifically target lysine 63 linked ubiquitin chains, which can negatively regulate the BCL-3, NF-κB and JNK signaling pathways, leading to a decreas
We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. The main difference of pathological changes in CXIIA rats against rats with CIIIA was a larger number of infiltrating lymphocy
The first modern Swedish checklist of fungus gnats of the families Bolitophilidae, Diadocidiidae, Ditomyiidae, Keroplatidae and Mycetophilidae is presented. The checklist results from a comprehensive literature research as well as treatment of a considerable determined and undetermined material from Swedish museum collections and recent material from several sources. To get better grounds for judg
Breast cancer is a truly heterogenous disease, reflected in the existence of a wide spectrum of phenotypic subsets of tumours with varying intrinsic aggressiveness as well as ability to respond to a given treatment. Recent advances in large-scale genomic and proteomic screening techniques have confirmed this heterogeneity also at a molecular level, but there is still a bottleneck to be overcome be
Popular Abstract in Swedish I Sverige bryter drygt 30 000 föräldrapar årligen upp från sin relation. Tillsammans har dessa föräldrar cirka 55 000 barn. I samband med föräldrarnas separation skall frågor om de gemensamma barnens vårdnad, boende och umgänge lösas. De flesta föräldrar klarar detta på egen hand eller med stöd av samarbetssamtal eller familjerådgivning, men ungefär 10% av de separerandThe purpose of this socio-legal dissertation is to examine the role of the district court in the handling of custody disputes, from the standpoint of the child's best interest. More specifically, the focus is partly on the relationship between the family and society during district court proceedings, and partly on the relationship between civil law and public law procedure that is to say between t
Popular Abstract in Swedish Efterfrågan på shikimsyra, vilken återfinns i biosyntesvägen för bl.a. de aromatiska aminosyrorna tryptofan, fenylalanin och tyrosin, har under de senare åren ökat. Orsaken till detta är mestadels att den är råmatrial till antiinfluensamedicinen Tamiflu?. Den ökade efterfrågan har drivit fram nya tillverkningsmetoder såsom produktion via E.coli- fermentation. Även om ma
Lactic acid bacteria (LAB), including Lactococcus lactis, are abundant in nature. These bacteria convert carbohydrates into mainly lactate by a rather uncomplicated metabolism. An improved understanding of the physiological and genetical mechanisms involved in carbohydrate metabolism and its regulation will improve the industrial use of LAB. The aim of this study was to investigate the maltose an
Urinary tract infection is the most common infection in man. P fimbriae are virulence factors of uro-pathogenic Escherichia coli. They are expressed by 70-90 % of acute pyelonephritis isolates and up to 100% of the most virulent isolates that cause bacteremia. This thesis concerns the interaction between P fimbriae and the urinary tract mucosa, and the host receptors involved in fimbrial recognit
Popular Abstract in English In our society powder is found to be a common state of material. Indeed, the powder state is found to be convenient to store and transport large quantities of material. One of the major techniques to produce powder is spray drying, also for thermally sensitive materials such as foods and pharmaceuticals. In spray drying a liquid is vaporized into a hot air stream, whichSpray drying is a preferred method to produce dry powder of thermally sensitive materials such as food and pharmaceuticals. Drying conditions and formulation determine primary properties such as morphology and composition that finally provide functionality such as dissolution, encapsulation and flowability. Even though spray drying is a well-established method to produce dry powder numerous challe
Ulf Johansson Dahre Introduction The 4th annual Somalia International Rehabilitation Centre (SIRC) Conference of the Horn of Africa focused on “Good Governance and the Rule of law” as keys to peace, development and sustainable development. The conference was held in Lund, Sweden, October 14-16, 2005. The content of this volume reflects some of the views and proceedings presented at the conference
The dinuclear species [(trispicMeen)(ClFeOFeCl)-O-III-Cl-III(trispicMeen)]Cl(OH)(H2O)(7) (1) (trispicMeen = N,N,N'-tris-(2-pyridylmethyl)-N'-methylethane- 1,2-diamine) was synthesized. It crystallizes in the monoclinic space group C2/c with a = 33.87(2) Angstrom, b = 17.42(2) Angstrom, c = 23.41(5) Angstrom, beta = 132.88(5)degrees, V = 10 121(25) Angstrom(3), and Z = 8. It contains an almost line
Real world systems are normally considered as hierarchically organized, for example, we see those as hierarchies of systems including subsystems. Examples on this can be seen in organizations where people act in environments and carry within themselves their own internal subsystem of thinking processes. Another example relates to robotics where robots may be seen as hierarchical constructions, bot
Popular Abstract in Swedish Avhandlingen behandlar tre områden: 1. implementeringen av Multisystemisk terapi (MST) som en behandlingsmetod inom socialtjänsten i Sverige, 2. implementeringen av ett forskningsprojekt vars mål är att utvärdera MST som behandlingsmetod, 3. utvärdering av MST som behandlingsmetod i jämförelse med traditionell behandling inom socialtjänsten för antisociala ungdomar. StuThis thesis focuses on three areas: 1. the implementation of Multisystemic Therapy (MST) as a treatment method in social services in Sweden, 2. the implementation of a research project that has the aim to evaluate MST as a treatment method, 3. the evaluation of MST as a treatment method compared to traditional social services for antisocial adolescents in Sweden. The first study reports on the imp
Popular Abstract in Swedish I hjärnan finns ett fantastiskt effektivt kontrollsystem för utförandet av olika typer av rörelser. Lillhjärnan är en viktig del av detta kontrollsystem eftersom skador på lillhjärnan kan leda till att fint styrda rörelser blir svårare eller kanske helt omöjliga att utföra. En förståelse av lillhjärnans funktion kan därför leda till en bättre generell förståelse av hur
Dreams & Discoveries LTH / FACULTY OF ENGINEERING / LUND UNIVERSITY Content: A place for dreams and disco veries .............. 3 To benefit the climate .................................... 8 To benefit digitalization .............................. 12 To benefit Industry ....................................... 16 To benefit the built environment ............... 20 To benefit life .................
https://www.lthin.lth.se/sites/lthin.lth.se/files/2025-05/Dreams%20and%20discoveries-compressed.pdf - 2026-06-22
lum_2008_06 lUm lunds universitets magasin | nr 6 | 2008 tillsammans igen efter 470 miljoner år tillsammans igen europatåg och cykel för hållbar semester djUPdykning mödan Värd 2 LUM nr 6 | 2008 hedersVakt LUM nr 6 | 2008 3 Pressuppbådet var ovanligt stort när doktorerna ställde upp för fo- tografering på universitetsplatsen. Mycket tack vare teologernas he- dersdoktor Jonas Gardell, men även Ekon
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-6-2008.pdf - 2026-06-22
Residual stress can be introduced unintentionally into the workpiece with various magnitudes and distributions through all manufacturing processes. These stresses have a significant effect upon the performance of the final component. Understanding the residual stress imparted by machining is an essential aspect of understanding the machining process and overall part quality. Although many investig
Popular Abstract in Swedish Jag har under min forskarutbildning vid Lunds tekniska högskola studerat proteiner med hjälp av en metod som kallas kärnmagnetisk resonans, NMR. I levande organismer regleras allt liv av tre typer av molekyler: DNA, RNA och proteiner. Den centrala dogmen i biokemi "DNA-RNA-Protein" innebär att den genetiska kod som ärvs i form av DNA och som finns i varje cell i kroppeThe general objective of the present thesis work was to examine 3-dimensional structure as well as the motional properties of two different types of two-domain proteins by solution-state NMR. One of the major tasks of this thesis work was to investigate the domain orientation of these molecules by employing residual dipolar couplings (RDC) which can be used as orientational restraints for increasi
Förevarande uppsats syftar till att utreda vilka drivkrafter som föregick och motiverade rättsutvecklingen inom prostitutionslagstiftningen mellan åren 1850 och 1999. Därtill redogör uppsatsen för hur statsmaktens inställning gentemot prostitution och prostituerade kvinnor tog sig uttryck i den legisla-tiva utvecklingsprocessen. Arbetet har genomförts med hjälp av en rättshisto-risk metod för att
I denna uppsats behandlas särskiljningsförmågan hos tredimensionella EU-varumärken. Med ett tredimensionellt varumärke avses något som består eller omfattar en tredimensionell form, däribland behållare, förpackningar, produkten i sig eller deras utseende. Att erhålla varumärkesskydd för en förpackning eller varan i sig ger många fördelar för den enskilde näringsidkaren. Varumärkesinnehavaren kan sThis thesis aims to investigate the criteria for assessing shape marks distinctive character as a European Union Trademark. Shape marks consist of, or extend to, a three-dimensional shape, including containers, packaging, the product itself or their appearance. Trademark protection for a shape mark provides, amongst other things, a protection against imitations and unfair advantage of the reputati
