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Avhandlingen består av fyra artiklar som alla kretsar kring hur ett effektivt nyttjande av infrastruktur kan uppnås. Tre av artiklarna berör externaliteter i transportsektorn medan den fjärde artikeln rör bostadsmarknaden och hur en skattereform påverkade äldre småhusägares flyttbeteende. Externaliteter uppstår när de beslut som en person (eller företag) tar har effekter även för andra och detta iAll four papers in the thesis share a common theme: how to achieve an efficient use of infrastructure and the built environment. In the presence of externalities, pricing according to the (short-run) marginal cost is one answer on how this can be achieved and the first two papers estimates parts of the marginal cost of traffic. Paper I examines the effect of road and railway noise on property pric

Singular perturbations of Schrödinger type operators are of interest in mathematics, e.g. to study spectral phenomena, and in applications of mathematics in various sciences, e.g. in physics, chemistry, biology, and in technology. They also often lead to models in quantum theory which are solvable in the sense that the spectral characteristics (eigenvalues, eigenfunctions, and scattering matrix) c

Popular Abstract in Swedish Ny kunskap gör det möjligt att med hjälp av DNA-information välja ut vilka kvigor/kor som förväntas ge en hög mjölkavkastning, höga halter av mjölkens komponenter och optimala egenskaper för ostproduktion. Denna information kan användas för att bättre anpassa mjölkens sammansättning och processegenskaper med de svenska mejeriernas behov för att på så vis förbättra mjölkMilk genomics is a new area of research that explores the relations between cow genetics and milk characteristics. Identifying the genes controlling compositional and technological traits of milk will give opportunities to select cows for targeted milk production. In this thesis, the impact of different genetic approaches, i.e. quantitative genetic evaluation, single gene effects and genomic selec

Periampullary adenocarcinoma, including pancreatic cancer, has a poor prognosis that has not improved in the last decades. Therefore, in order to find more effective treatment regimens, it is necessary to gain more insight into the biology and clinical behaviour of these tumours. This thesis entails a thorough histopathological characterization of retrospectively collected tumours from a consecuti

Molecularly imprinted polymers (MIPs) are artificial receptors designed for the selective recognition of template molecules. These polymers have been applied in analytical separations, as chemical sensors and in drug delivery system due to their low cost and high stability. In recent years MIP beads, especially those with good selectivity in aqueous solution, have become attractive as they can be

This thesis explores the use of data mining and AI-tailored frameworks for extracting public health evidence from large health datasets. The research presented in this thesis demonstrates the potential of these tools for automating and simplifying the data mining process, and for providing valuable insights into various public health issues.In Paper I, we used data mining and natural language proc

The present study was aimed at identifying genetic variants in susceptibility to childhood acute lymphoblastic leukemia (ALL) through replication and validation of polymorphisms selected from two genome wide association studies. The first part of the study was based on the replication of polymorphisms selected from a previously conducted genome wide scan using 50K DNA-SNP microarrays. 47 selected

Lärares praktiska yrkeskunskaper bjuder motstånd mot förspråkligande. Detta problem föreligger inte minst i lärarutbildningen, där det i verksamhetsförlagda delar kan råda både osäkerhet och skilda uppfattningar om vad studenterna behöver göra eller prestera för att uppnå de mål som (bokstavligen) föreskrivits dem. Syftet med avhandlingen har varit att beskriva och förstå villkor och förutsättning

The advent of PET ligands that bind tau pathology has enabled the quantification and visualization of tau pathology in aging and in Alzheimer disease (AD). There is strong evidence from neuropathologic studies that the most widely used tau PET tracers (i.e., 18F-flortaucipir, 18F-MK6240, 18F-RO948, and 18F-PI2620) bind tau aggregates formed in AD in the more advanced (i.e., ≥IV) Braak stages. Howe

The global temperature rise is proportional to the cumulative amount of CO2 emissions to the atmosphere. This observation is consistent between climate models and historical observations. It has also given rise to the concept of a carbon budget, which sets a threshold for the amount of CO2 that can be emitted into the atmosphere while still fulfilling political goals such as the Paris Agreement.Te

The enormous production and consumption of fossil-based plastics has caused severe environmental challenges such as pollution of the ocean, increased CO2-emissions, and various health problems. Many ofthese concerns are intimately connected to the use of fossil fuels in the production of polymers. For this reason, there is a considerable interest to develop bio-based monomers to mitigate some of t

This research focuses on the contemporary case study of the Thawra Chronicles, founded by three London-based members of the Lebanese diaspora in the wake of the Lebanese Revolution in early October 2019 to support the social movement from afar, targeting non-Lebanese individuals as well as Lebanese within and beyond its borders. Thawra Chronicles is a multifaceted, independent alternative online o

Altering the fate of newborn cells in the hippocampus after status epilepticus Epilepsy is a common neurological disorder that is estimated to affect approximately 50 million people around the world according to the World Health Organization. This disorder is characterized by an increase in the predisposition to generate seizures, which are periods of hyperexcitable neuronal signaling. The treatm

Det finns ett antal faktorer som krävs för att en ekonomi ska kretsa fritt utan störningar eller stagnation. Några av dessa faktorer är förstås på nationalekonomisk basis, andra är juridiska. Många av de juridiska åtgärder som vidtas på lagstiftningsnivå är i syfte att främja handel, utan att en part ska stå en för stor ekonomisk risk i händelse av motpartens oförmåga eller ovilja att betala sin sAn economy is dependent on numerous different factors to function without interference and stagnation. Many of those aspects are solely financial in nature, and some are legal. Many of the legislative measures taken to benefit the national economy fill the purpose of creating an incentive for trade, without the risk of suffering a great loss because of the counterpart’s inability or lack of will t

I asylmål med sexuell läggning som grund för förföljelse utgör den sökandes berättelse oftast den främsta och ibland enda bevisningen. Utifrån en bevisvärdering av den muntliga utsagan avgörs således om den sexuella läggningen har gjorts sannolik och om sökanden därmed kan åtnjuta skydd som flykting. Fokus för prövningen blir alltså en trovärdighetsbedömning av sökanden och dennes berättelse. Mot In refugee claims, where the applicant is seeking asylum on account of a well-founded fear of being persecuted because of his or her sexuality, the applicant’s own testimony is usually the primary evidence. Therefore, the authorities and the courts have to evaluate whether the applicant has made his or her sexual orientation plausible, and consequently is able to enjoy protection as a refugee, by