Sökresultat

The present study was aimed at identifying genetic variants in susceptibility to childhood acute lymphoblastic leukemia (ALL) through replication and validation of polymorphisms selected from two genome wide association studies. The first part of the study was based on the replication of polymorphisms selected from a previously conducted genome wide scan using 50K DNA-SNP microarrays. 47 selected

Lärares praktiska yrkeskunskaper bjuder motstånd mot förspråkligande. Detta problem föreligger inte minst i lärarutbildningen, där det i verksamhetsförlagda delar kan råda både osäkerhet och skilda uppfattningar om vad studenterna behöver göra eller prestera för att uppnå de mål som (bokstavligen) föreskrivits dem. Syftet med avhandlingen har varit att beskriva och förstå villkor och förutsättning

The advent of PET ligands that bind tau pathology has enabled the quantification and visualization of tau pathology in aging and in Alzheimer disease (AD). There is strong evidence from neuropathologic studies that the most widely used tau PET tracers (i.e., 18F-flortaucipir, 18F-MK6240, 18F-RO948, and 18F-PI2620) bind tau aggregates formed in AD in the more advanced (i.e., ≥IV) Braak stages. Howe

The global temperature rise is proportional to the cumulative amount of CO2 emissions to the atmosphere. This observation is consistent between climate models and historical observations. It has also given rise to the concept of a carbon budget, which sets a threshold for the amount of CO2 that can be emitted into the atmosphere while still fulfilling political goals such as the Paris Agreement.Te

The enormous production and consumption of fossil-based plastics has caused severe environmental challenges such as pollution of the ocean, increased CO2-emissions, and various health problems. Many ofthese concerns are intimately connected to the use of fossil fuels in the production of polymers. For this reason, there is a considerable interest to develop bio-based monomers to mitigate some of t

This research focuses on the contemporary case study of the Thawra Chronicles, founded by three London-based members of the Lebanese diaspora in the wake of the Lebanese Revolution in early October 2019 to support the social movement from afar, targeting non-Lebanese individuals as well as Lebanese within and beyond its borders. Thawra Chronicles is a multifaceted, independent alternative online o

Altering the fate of newborn cells in the hippocampus after status epilepticus Epilepsy is a common neurological disorder that is estimated to affect approximately 50 million people around the world according to the World Health Organization. This disorder is characterized by an increase in the predisposition to generate seizures, which are periods of hyperexcitable neuronal signaling. The treatm

Det finns ett antal faktorer som krävs för att en ekonomi ska kretsa fritt utan störningar eller stagnation. Några av dessa faktorer är förstås på nationalekonomisk basis, andra är juridiska. Många av de juridiska åtgärder som vidtas på lagstiftningsnivå är i syfte att främja handel, utan att en part ska stå en för stor ekonomisk risk i händelse av motpartens oförmåga eller ovilja att betala sin sAn economy is dependent on numerous different factors to function without interference and stagnation. Many of those aspects are solely financial in nature, and some are legal. Many of the legislative measures taken to benefit the national economy fill the purpose of creating an incentive for trade, without the risk of suffering a great loss because of the counterpart’s inability or lack of will t

I asylmål med sexuell läggning som grund för förföljelse utgör den sökandes berättelse oftast den främsta och ibland enda bevisningen. Utifrån en bevisvärdering av den muntliga utsagan avgörs således om den sexuella läggningen har gjorts sannolik och om sökanden därmed kan åtnjuta skydd som flykting. Fokus för prövningen blir alltså en trovärdighetsbedömning av sökanden och dennes berättelse. Mot In refugee claims, where the applicant is seeking asylum on account of a well-founded fear of being persecuted because of his or her sexuality, the applicant’s own testimony is usually the primary evidence. Therefore, the authorities and the courts have to evaluate whether the applicant has made his or her sexual orientation plausible, and consequently is able to enjoy protection as a refugee, by

Freeze damage is a common issue in many food items. The cellular dehydration caused by freezing can be prevented through addition of a cryoprotectant. Research has shown that it is possible to improve the freezing tolerance of plant materials by addition of cryoprotectants, which forms hydrogen bonds with water molecules. However, the cryoprotect needs to be in the cell to function. Which is where

Purpose: To study the effect of environmentally-relevant personal values (biospheric, altruistic, egoistic and hedonic) on the purchase intention of second-hand clothing (SHC). Methodology: This research is a quantitative study and follows a deductive research approach. The empirical data was obtained through convenience sampling by means of an online self-completion questionnaire. A total of 669

Distribution is a part of the supply chain and refers to the steps taken to move and store a product from the supplier stage to the customer stage in the supply chain. Direct shipment is a concept within distribution and refers to shipping direct between a supplier and a retailer or customer. Distribution is considered a key driver for overall profitability of a company since it directly affects b

Sammanfattning Denna uppsats undersöker sambandet mellan polisens utredningsåtgärder och personuppklaring och lagföring vid hedersrelaterad brottslighet. Det övergripande syftet är att redogöra för vilken betydelse rätt kunskap, förstahandsåtgärder och utredningsmetodik spelar för den fortsatta lagföringen. Jag vill också undersöka om den kunskapssatsning som gjorts av regeringen och rikspolisstyrThis thesis investigates the connection between police investigative measures, solved crimes and prosecution concerning honour related crime. The overall aim is to account for what significance correct knowledge, first measures taken and methods used during the investigation have for the following prosecution. I also wish to investigate whether the augmentation of knowledge initiated by the govern

Kvinnliga samkönade par har tillgång till insemination inom svensk sjukvård sedan den 1 juli 2005. Trots det väljer en del par att genomföra behandlingen utanför svensk sjukvård, antingen utomlands eller genom privat insemination. Vid insemination utanför svensk sjukvård med donerad sperma skiljer sig föräldraskapsregleringen för kvinnliga samkönade par från den för olikkönade par. Mannen i ett olFemale same-sex couples have had the right to undergo insemination within Swedish health care since July 1st 2005. Despite this some couples still choose to get the treatment outside Swedish health care, either abroad or through private insemination. With insemination outside Swedish health care with donated sperm the regulation for parenthood for female same-sex couples differs from that of oppos