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The number and volume of cells in the blood affect a wide range of disorders including cancer and cardiovascular, metabolic, infectious and immune conditions. We consider here the genetic variation in eight clinically relevant hematological parameters, including hemoglobin levels, red and white blood cell counts and platelet counts and volume. We describe common variants within 22 genetic loci rep
Neural interfaces hold great promise to become invaluable clinical and diagnostic tools in the near future. However, the biocompatibility and the long-term stability of the implanted interfaces are far from optimized. There are several factors that need to be addressed and standardized when improving the long-term success of an implanted electrode. We have chosen to focus on three key factors when
Mantle cell lymphoma (MCL) is a distinct subtype of malignant lymphoma which is characterized by the chromosomal translocation t(11;14)(q13;q32) resulting in constitutional overexpression of cyclin D1 and cell cycle dysregulation in almost all cases. Clinically, MCL shows an aggressive clinical course with a continuous relapse pattern and a median survival of only 3-5 years. However, recently a su
The functionality of modern automotive vehicles is becoming increasingly dependent on control systems. Active safety is an area in which control systems play a pivotal role. Currently, rule-based control algorithms are widespread throughout the automotive industry. In order to improve performance and reduce development time, model-based methods may be employed. The primary contribution of this the
The EU has a normative character in its foreign policy. While dealing with its relationship with the neighbours, the EU pays attention to exporting its norms. The enlargement policy is evidence of the EU’s normative power. However, from ENP to EaP, the EU seems not so effective in promoting normative changes in the target states. The existing researches lack a deep and comprehensive analysis of th
Cross-border investments made through investment funds are still surrounded by uncertainty, derived by the inexistence of harmonization of direct taxation in the European Union. The uncertainty surrounding the tax treatment, especially in cross-border situations, tend to trigger tax issued such as discrimination and restrictions to fundamental freedoms. More than 3000 funds have claimed a full ref
The purpose of this study was to analyze how does China pursue its national interest in the governance of the Lancang- Mekong River in domestic and international terms. The analysis was done through the lens of the classical realism theoretical school. Drawing from this framework and adopting the concept of national interest, the study gave a deeper understanding of China‟s motives behind the Lanc
In Swedish higher education, the students have a right by law to partake in the decisions that concern them and the education. The participation in such decisions is organized through student representatives elected by the student unions. Previous studies on representation in student unions and politics suggested that a certain socioeconomic background might be overrepresented among the student un
In September of 2018, a total of 261 concerned public servants within the Government Offices issued an internal letter to the chief of Administrative affairs. The letter voiced the concerns of the public servants regarding what would happen to their staff policy, if a known right-wing party would be elected for government that year. When this was made public knowledge, a debate sparked amongst dif
Human trafficking is the third largest illegal source of income, after drugs and weapon. The purpose of this study is to investigate why people fall victims for human trafficking and to study wherein the court of justice discusses the victims social background in their court-‐‑cases. That is to say, the circumstances that is beyond the borders of Sweden. The essay also highlights how aid organiza
Abstract: The severity of the crisis in the Southern Eurozone countries is frequently attributed to inflated economies and reckless spending. Thus, it isn’t surprising that the main interpretation is that the crisis ought to be solved by decreasing government spending and lowering wages. This paper argues, instead, that one of the core underlying reasons for the severity of the crisis in the South
