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This article is based on a keynote presentation at the 12th Nordic Congress in General Practice in Trondheim, Norway in September 2002. The aim was to demonstrate the strengths and limitations of evidence-based medicine (EBM) in a primary healthcare setting. The presentation comprised two separate lectures discussing an authentic case history from everyday practice that had been presented to the a

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Abstract in UndeterminedDiabetic foot complications result in huge costs for both society and the individual patients. Few reports on the health-economic consequences of diabetic foot infections have been published. In studies considering a wide societal perspective, costs of antibiotics were relatively low, whereas total costs for topical treatment were high relative to the total costs of foot in

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This paper presents an account of the progress of the integration between the Danish and Swedish parts of the Öresund Region within the world of science, with emphasis on biotech. The paper is based on data from the database Science Citation Index Expanded. The amount of co-authorships produced by agents from each side of the region is analysed for a 12-year period (1994–2005) and used as an indic

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A variety of contractile agonists trigger activation of the small GTPase RhoA. An important target of activated RhoA in smooth muscle is Rho-associated kinase (ROK), one of the downstream targets that is the myosin binding subunit (MYPT1) of myosin light chain phosphatase (MLCP). Phosphorylation of MYPT1 at T695 by activated ROK results in a decrease in phosphatase activity of MLCP and an increase

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The sand-steppe is a unique vegetation type almost exclusively found in eastern Scania. It is dominated by rare species such as Koeleria glauca, Festuca polesica, Phleum arenarium, Dianthus arenarius, Astragalus arenarius, Anthericum ramosum and Syntrichia ruraliformis. In 1994, the area covered by this vegetation was estimated to be 57 ha but in the present study only 20-30 ha were refound. Prere