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The process of selecting requirements for a release of a software product is challenging as the decision-making is based on uncertain predictions of customer value and development cost. This paper presents a method aimed at supporting software product development organisations in the identification of process improvement proposals to increase requirements selection quality. The method is based on

As counter intuitive as it might sound, autocracy without elections is a rare combination today. Elections do not constitute democracy, but they can promote democratization. This dissertation studies the process of democratization through elections, focusing on the effect of opposition coordination. Several authors have stressed the importance of opposition coordination as an explanation for democ

This thesis concerns a sociological analysis on the role of generations in the processes of the construction of national identities, and long-distance nationalism in diasporic settings. The empirical case taken is a political generation of Kurds from Turkey who once arrived in Sweden as political refugees. The primary aim of the thesis is to study how national identities are constructed and maint

Methods currently used for inventory control in industry are with few exceptions developed more than forty years ago. This is for instance the case with methods like reorder point sys-tems, cover-time planning and material requirements planning (MRP). Lead times at that time were typically several weeks and months and order quantities covered typically de-mand over several months. Since then both

Thrombotic microangiopathy is the pathological lesion found in hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP) as well as other conditions. It manifests as damaged endothelial cells in small vessels with deposits of platelet plugs, occlusion of vessels, decreased blood flow and secondary organ insufficiency. HUS is characterized by microangiopathic hemolytic anemia, thro

Primary defence against invading microorganisms depends on a functional innate immune system and the complement system plays a major role in such immunity. Deficiencies in one of the components of the complement system can cause severe and recurrent infections, systemic diseases, such as systemic lupus erythematosus (SLE) and renal disease. Screening for complement deficiencies in the classical or

Sequential Monte Carlo (SMC) methods have demonstrated a strong potential for inference on the state variables in Bayesian dynamic models. In this context, it is also often needed to calibrate model parameters. To do so, we consider block maximum likelihood estimation based either on EM (Expectation-Maximization) or gradient methods. In this approach, the key ingredient is the computation of smoot

BACKGROUND: Vascular endothelial dysfunction, accelerated thickening of arterial intima, and changes in ventricular repolarization contribute to increased cardiovascular morbidity in type 1 diabetes (T1D). Although vitamin C has important antioxidant functions and increased oxidative stress is a central mechanism of cardiovascular dysfunction in T1D, the relation between vitamin C and the cardiova

BACKGROUND: Retinoic acid (RA) and fibroblast growth factor 4 (FGF4) signaling control endoderm patterning and pancreas induction/expansion. Based on these findings, RA and FGFs, excluding FGF4, have frequently been used in differentiation protocols to direct differentiation of hESCs into endodermal and pancreatic cell types. In vivo, these signaling pathways act in a temporal and concentration-de