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We have recently shown that the human Nuclear pore-associated protein (NPAP1)/C15orf2 gene encodes a nuclear pore-associated protein. This gene is one of several paternally expressed imprinted genes in the genomic region 15q11q13. Because the Prader–Willi syndrome is known to be caused by the loss of function of paternally expressed genes in 15q11q13, a phenotypic contribution of NPAP1 cannot be e
The idea that excitonic (electronic) coherences are of fundamental importance to natural photosynthesis gained popularity when slowly dephasing quantum beats (QBs) were observed in the two-dimensional electronic spectra of the Fenna–Matthews–Olson (FMO) complex at 77 K. These were assigned to superpositions of excitonic states, a controversial interpretation, as the strong chromophore–environment
The local governments of EU member countries are attracted to the possibility of receiving EU funding. However, as the governance structures of EU funds are complex and dynamic, municipalities are increasingly drawing on the knowledge and resources of ‘EU experts’ who mediate and provide project support. This article contributes to our understanding of how EU cohesion policy is translated through
The present study was conducted to investigate heat transfer enhancement from the endwall of a protruding circular cylinder by addition of a winglet vortex generator pair. A steady-state liquid crystal thermography technique was employed. The vortex generator pair is installed upstream of a cylinder placed either in counter flow inward or counter flow outward orientation. The vortex generator inst
Nitrifiers are the slowest growing bacteria used in conventional biological wastewater treatment. Furthermore, their growth rate is seriously hampered by low temperature. As a result, the volume needed for nitrification dominates the volume of the biological reactors at a wastewater treatment plant. As a way of enhancing nitrification and reducing this volume, bioaugmentation can be used. Nitrifie
Several studies have proposed that small- and medium-sized enterprises (SMEs) lack resources and experiential knowledge to internationalise to distant markets. The authors argue that SMEs can handle the lack of these tangible and intangible internal resources through external collaborations; they can achieve success in international markets by collaborating with business partners. The role of inte
At the Rio Earth Summit of 1992 governments undertook to develop and adopt national sustainable development strategies as a key component of implementing the goals of Agenda 21. Only partial progress was reported at the 2002 World Summit in Johannesburg, with uncertainty as to the effectiveness of those strategies that had been introduced. This paper describes a methodology for assessing a country
Drug-related problems in the elderly is intended to serve as a source of information and clinical support in geriatric pharmacotherapy for students as well as all health care professionals, e.g. physicians, nurses and pharmacists. Pharmacotherapy is of great importance to all mankind. Drugs are however powerful and must be handled appropriately. This is especially important for elderly patients. D
In rhizosphere Plant Growth Promoting Rhizobacteria (PGPR) produce N-acyl-l-homoserine lactones (AHL) as the quorum-sensing (QS) signals. AHLs can act as trans-kingdom signalling molecules between plants and rhizobacteria and that can regulate plant growth and development. The plant-beneficial PGPR Burkholderia phytofirmans PsJN promotes growth in Arabidopsis thaliana by producing 3-oxo-dodecanoyl
Background: Brain reserve is a concept introduced to explain why Alzheimer's disease (AD) patients with a greater brain volume prior to onset of pathology generally have better clinical outcomes. In this review, we provide a historical background of the emergence of brain reserve and discuss several aspects that need further clarification, including the dynamic or static nature of the concept and
Within the scope of the debate surrounding globalization, ever increasing attention is being directed to the growth of border-crossing social relations and the emergence of transnational social spaces on the micro-level. In particular, the question of how these border-crossing interrelations influence the attitudes and values of the people involved causes some controversy. Some assume that the inc
This article takes the plan drawing of Richard Meier’s Westbeth Artists’ Colony in Greenwich Village as a lens through which to examine a chain of events that formalised what today is referred to as loft architecture. Westbeth was the first legal loft building in the USA. Approved by the local planning administration in March, 1968, and completed in May, 1970, the building was the successful culmi
Importance: Targeted alpha therapy attempts to deliver systemic radiation selectively to cancer cells while minimizing systemic toxic effects and may lead to additional treatment options for many cancer types. Observations: Theoretically, the high-energy emission of short-range alpha particles causes complex double-stranded DNA breaks, eliciting cell death. No known resistance mechanism to alpha p
