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Where do we go from here? Market access and regional development in Italy (1871–1911)
Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
Digital containment : Revisiting containment strategy in the digital age
Signatures of Wigner localization in epitaxially grown nanowires
How do episodic and semantic memory contribute to episodic foresight in young children?
Model-Based Comparison of Batch and Continuous Preparative Chromatography in the Separation of Rare Earth Elements
The demand for rare earth elements (REEs) is growing, while the future supply is uncertain. Their unique electronic characteristics make them irreplaceable, and the commercial value of pure fractions is high. A model-based simulation study is presented that compares batch chromatography with the twin-column MCSGP (multicolumn countercurrent solvent gradient purification) process for ion-exchange c
Investigation of Medication Dosage Influences from Biological Weather
Dipolar Order in Molecular Fluids: II. Molecular Influence
A protein deep sequencing evaluation of metastatic melanoma tissues.
Malignant melanoma has the highest increase of incidence of malignancies in the western world. In early stages, front line therapy is surgical excision of the primary tumor. Metastatic disease has very limited possibilities for cure. Recently, several protein kinase inhibitors and immune modifiers have shown promising clinical results but drug resistance in metastasized melanoma remains a major pr
A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
Background: Allergic contact dermatitis is an inflammatory skin disease that affects a significant proportion of the population. This disease is caused by an adverse immune response towards chemical haptens, and leads to a substantial economic burden for society. Current test of sensitizing chemicals rely on animal experimentation. New legislations on the registration and use of chemicals within p
Breast Cancer Screening With Tomosynthesis-Initial Experiences
Experiences gained so far using tomosynthesis for breast cancer screening will be reported. A short summary of results from preparatory studies will also be presented. The sensitivity and specificity of breast tomosynthesis (BT) will be compared with conventional two-dimensional digital mammography (DM) for breast cancer screening in a population-based study. Over 2000 women have been examined so
Structure changes in Er-160 from low to ultrahigh spin
Search for diphoton events with large missing transverse momentum in 7 TeV proton-proton collision data with the ATLAS detector
On the calculation of the structure of charge-stabilized colloidal dispersions using density-dependent potentials
An approach to constraint-based and mass-customizable product design
In traditional product development, several iterations are usually necessary to obtain a successful compromise between constraints emanating from engineering, manufacturing, and aesthetics. Moreover, this approach to product development is not well suited for true mass-customization, as the manufacturing company remains in control of all aspects of the shape of the product-to-be. In this article,
A search for t (t)over-bar resonances with the ATLAS detector in 2.05 fb(-1) of proton-proton collisions at root s=7 TeV
Cyclic carbonates as monomers for phosgene- and isocyanate-free polyurethanes and polycarbonates
Polyurethanes and polycarbonates are widely used in a variety of applications including engineering, optical devices, and high-performance adhesives and coatings, etc., and are expected to find use also in the biomedical field owing to their biocompatibility and low toxicity. However, these polymers are currently produced using hazardous phosgene and isocyanates, which are derived from the reactio
