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As researchers we are often faced with the difficult and demanding task of preparing models, and their computer implementations, for decision making, or, more recently, for integrated assessment. Such assessment often involves large scale problems, where the decisions to be made can deeply affect the environment, the social context and the economic background of regions and even nations. Yet, we f
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with mutations in the NPM1 gene occurring in almost one third of all cases. The ability to detect residual leukemia below the resolution of conventional microscopy is crucial for evaluation of relapse risk after therapy. In principle, this can be achieved by measuring residual disease (MRD) with two different approac
During the 1980s the word ’postmodernism’ was inserted into the dicourse of Swedish literature in a curious way. Even though both writers and critics found the word bewildering – or deemed it a buzzword devoid of meaning – it sparked fierce debates. Despite this, and despite the fact that few wanted to be associated with the word, it has become common to describe the 1980s as the era of Swedish li
Sedan 1999, när den nya inkomstskattelagen (SFS 1999:1229) trädde i kraft har det i svensk skattelagstiftning funnits tre alternativa rekvisit som stadgar när en fysisk person ska anses vara obegränsat skattskyldig för sina globala inkomster i Sverige. I denna uppsats undersöks ett av dessa tre rekvisit, nämligen det som handlar om att den som stadigvarande vistas i Sverige är obegränsat skattskylSince 1999, when the new Income Tax Act (SFS 1999:1229) came into force, Swedish tax legislation has contained three alternative criteria stipulating when a natural person is to be considered liable for unlimited tax on their global income in Sweden. This essay examines one of these three criteria, namely that a person who resides permanently in Sweden is subject to unlimited tax liability, as sta
Följande uppsats analyserar det straffrättsliga ansvaret vid olyckor orsakade av självkörande fordon. Dessa självkörande fordon styrs av avancerade artifi-ciella algoritmer som fattar autonoma beslut, vilket utmanar straffrättens grundläggande krav och principer. Bland annat blir maximet ”nulla poena sine culpa” (inget straff utan skuld) lidande när beslutsprocessen i gärningsögon-blicket saknar tThe following thesis analyzes criminal liability in accidents caused by self-driving vehicles. These autonomous vehicles are governed by advanced artifi-cial algorithms that make autonomous decisions, which challenges the funda-mental requirements and principles of criminal law. Among other things, the maxim "nulla poena sine culpa" (no punishment without guilt) suffers when the decision
The business potential of software defined radio (SDR) technology is studied by evaluating whether or not its characteristics correspond to those particular to a disruptive technology. The maturity of the SDR technology concept is illuminated by analyzing the opinions and perspectives of a selection of representatives for different stakeholders in the wireless communications market. Characteristic
Adult neural stem/progenitor cells (NSPs) are multipotent and self-renew over an extensive period of time. Transformation events in such cells, such as genetic or epigenetic alterations can result in brain tumors. One goal of research on brain tumors is to identify which regulators are impaired during tumor initiation, development and maintenance in order to understand the origin of brain tumors a
Diversity in lifestyles and socioeconomic status among European populations, and recent socio-political and economic changes in transitional countries, may affect changes in adiposity. We aimed to determine whether change in the prevalence of obesity varies between the socio-politically transitional North-East European (Łódź, Poland; Szeged, Hungary; Tartu, Estonia), and the non-transitional Medit
Barns internetanvändning äger i stor utsträckning rum i en kommersiell miljö där reklam och försäljning av virtuella föremål är ständigt närvarande. Genom att kombinera publikforskning, produktionsforskning samt textanalys (observationer online och dokumentanalys) bidrar denna avhandling till en kritisk förståelse av internet som en plats för barns vardagliga aktiviteter och deltagande, och som enChildren’s daily internet usage takes place to a large extent in a commercial environment, where advertising and the sale of virtual goods are ever-present parts of the online experience. The overall goal of this thesis is to contribute to a critical understanding of children’s commercial online environment as spaces for children’s everyday life activities and participation, and as spaces for comm
Popular Abstract in Swedish Att klara sig trots allt: Den sociala och produktiva dynamiken hos småbönderna i de halvtorra områdena i Iringa i norra Tanzania. Det är inte lätt att överleva som småbonde i de halvtorra områdena i Iringa och på liknande platser i Afrika. Man kontrollerar knappast sin egen livssituation. Regnen är opålitliga, priser, marknadsföring och politiska ingrepp är oförutsägbaWhile much of semi-arid Africa is still sparsely populated with unused land, there are everywhere pockets of high and increasing population density in attractive locations. Small-scale farmers can respond to beginning land-scarcity in a number of ways. Through migration, through diversification of livelihoods, or through changes in their farming system. Which solution is chosen, depends not only o
Under de senaste 10 åren har cirka en miljon människor sökt asyl i Sverige varav hela 163 000 enbart under 2015 när den stora flyktingvågen tog fart i världen. Detta satte stor press på Sveriges hantering av flyktingar och framförallt kommunernas bostadsförsörjningsansvar. Den 1 mars 2016 införde regeringen beslutet att kommunerna är skyldiga att ta emot ett visst antal nyanlända i syfte att ge deDuring the last 10 years approximately one million people have applied for asylum in Sweden and 163 000 only during the big stream of immigrants in 2015. This put a huge pressure on the Swedish management of immigrants and the housing for this group of people. The 1st of March 2016 the Swedish Government introduced a law where the Swedish municipalities are obligated to receive a certain number of
Förevarande uppsats syftar till att utreda vilka drivkrafter som föregick och motiverade rättsutvecklingen inom prostitutionslagstiftningen mellan åren 1850 och 1999. Därtill redogör uppsatsen för hur statsmaktens inställning gentemot prostitution och prostituerade kvinnor tog sig uttryck i den legisla-tiva utvecklingsprocessen. Arbetet har genomförts med hjälp av en rättshisto-risk metod för att This paper aims to investigate the driving forces that preceded and motivated the developments of the law in legislation concerning prostitution between the years of 1850 and 1999 in Sweden. Further more, the paper describes how the state's attitude towards prostitution and prostituted women was expressed in the legislative development process. The work has been undertaken using a legal-histor
Syftet med den här uppsatsen är att utvärdera förslagen gällande beskattning av den digitala ekonomin genom införandet av en betydande ekonomisk närvaro (SEP), betydande digital närvaro (SDP) eller införandet av en källskatt. För att på ett grundligt sätt förstå utmaningarna med beskattning av den digitala ekonomin använder jag det svensk-brittiska skatteavtalet för att ge ett konkret exempel på hThe purpose of this thesis is to examine the proposals to tax the digital econ-omy by introducing a significant economic presence (SEP), significant digital presence (SDP) or a withholding tax. To fully understand the challenges of taxing the digital economy, I use the Sweden-UK tax treaty to provide a concrete example of how digital business is handled in practice. The tax treaty is used as a too
I den rättspolitiska debatten pekar vissa åklagare på ett växande problem – att misstänkta utnyttjar rätten till tystnad genom att framföra sin berättelse först under huvudförhandlingen då de fått ta del av all bevisning. Detta sägs leda till felaktiga frikännande domar på grund av omedelbarhetsprincipen. I denna kontext har förslag om att införa en variant av Danmarks grundlagsförhör och deras beIn the ongoing legal debates, some prosecutors highlight a growing problem – that suspects seem to be exploiting the right to silence by holding back their statements until the main hearing after they've seen all the evidence. They argue that this tactic leads to wrongful acquittals due to the principle of immediateness. In this context, proposals to introduce a variant of Denmark's consti
Att det dödliga våldet har ökat de senaste åren är svårt att undgå. Speciellt har våldet ökat inom den kriminella miljön. Detta ställer högre krav på både de brottsbekämpande myndigheterna och lagstiftaren i att skapa nya och fler åtgärder för att bekämpa denna brottslighet. En av dessa åtgärder har varit att utöka möjligheten för bland annat polisen att använda sig av hemlig avlyssning av elektroThe fact that the deadly violence has increased in recent years is hard to circumvent. It is within the criminal environment that the deadly violence has increased particularly. This places higher demands on both the law enforcement authorities and the legislature in creating new and more measures to combat this criminal behavior. One of these measures has been to expand the possibility for the po
Uppsatsen undersöker om det rättsliga stödet för sekretess enligt 21 kap. 7 § offentlighets- och sekretesslagen (OSL) uppfyller legalitetsprincipens krav. Av 21 kap. 7 § offentlighets- och sekretesslagen (OSL) framgår det bl a. att sekretess gäller för personuppgifter, om det kan antas att uppgiften efter ett utlämnande kommer att behandlas i strid med dataskyddsförordningen (GDPR) eller dataskydThe essay investigates whether the legal basis for confidentiality according to the 21st chapter 7 § of the Public Access to Information and Secrecy Act (OSL) is in fulfillment of the demands that follow the principle of legality. According to the 21st chapter 7 § OSL, confidentiality applies to personal data if it can be assumed that, after being disclosed, the data will be pro-cessed in violati
Soon after the annexation of Crimea by the Russian Federation in March 2014, a peak moment in the events commonly referred to as the Ukraine crisis (Wilson A, Ukraine crisis. What it means to the West? Yale University Press, New Haven, 2014), media in Estonia and abroad started to speculate about whether Russia would stop at Crimea, or if Estonia, with its sizable Russian-speaking minority, would
-The purpose of this work is to investigate and identify the most efficacious methods to optimize train maintenance and operations during winter months. The study analyzes scheduled and unscheduled maintenance problems during winter months and considers various options on how to streamline current methods and procedures by identifying key areas and addressing optimization. This study presents prop
Popular Abstract in English In an organism the DNA contains the entire biological information that is needed to be able to exist and function. Those segments, also known as DNA sequences are a genetic code, which is further packaged into units called genes. The entity of all genes is called genome. Today we know, that only a small proportion of genes encode for proteins, which are responsible for More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. Transposable elements comprise about 50% of the genome and co-exist as symbio
This Norm focussing article starts exploring the various influence processes that take place in connection with the dawn of a new theme - the environment and then sustainable development - in today's society. The Swedish society has in the early 1990-ies declared that educational institutions, places designed for the intentional influence, shall utilise the new environmental theme in its practice.
