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Combining crystallography with quantum mechanics

In standard crystallographic refinement of biomacromolecules, the crystallographic raw data are supplemented by empirical restraints that ensure that the structure makes chemical sense. These restraints are typically accurate for amino acids and nucleic acids, but less so for cofactors, substrates, inhibitors, ligands and metal sites. In quantum refinement, this potential is replaced by more accur

Intrinsic subtypes and prognostic implications in epithelial ovarian cancer

Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. However, ovarian cancer is a heterogeneous disease comprising different disease entities, which is of importance in clinical decision-mak

Management of saltpans as potential foraging sites for shorebirds

Abstract Estuaries and salt marshes are important wetlands used by waterbirds during winter and migration. However, many salt-marshes have been transformed into salinas, which currently function as high-tide roosts. Since traditional salt production is no longer profitable, many salinas have been abandoned or converted into aquaculture potentially becoming less attractive to waders. In this study

Developing A Proactive Safety Performance Measurement Tool (SPMT) For Construction Sites

‘Safety pays’ is a phrase commonly used. But, when it comes to putting that concept into practice, very few are actually successful at it. Reasons given include: it is costly or it is a waste of time or it is not the main cause of failure. However the real problem is that there is not enough guidance as to how to improve safety performance on site. Traditional measurement approaches include accide

E-mobility charging sites. Assessment of power system impacts, consumption patterns and feasibility aspects to explore a new business opportunity.

Electrification of energy demand is seen as one of the key elements of energy transition toward decarbonisation. E-mobility is one main side of the electrification process, and it is considered as a crucial way to reduce the emissions of the transport sector. A core element for a widespread adoption of electric vehicles (EVs) is the deployment of the charging infrastructure, and installing a micro

Fighting the world's worst aquatic weed - A comparison of management methods for Water hyacinth (Eichhornia crassipes) in Australia and South Africa

The Water hyacinth is one of the worst aquatic weeds in the world and it is today present on all continents except Antarctica. It causes big problems for both people and the aquatic ecosystems in many countries. A lot of research has been completed to find methods to eradicate the weed and a lot of money has been spent on management to keep waters clean. In this literature study on management meth

Daily global solar radiation time series prediction using variational mode decomposition combined with multi-functional recurrent fuzzy neural network and quantile regression forests algorithm

Global solar radiation (GSR) prediction capability with a reliable model and high accuracy is crucial for comprehending hydrological and meteorological systems. It is vital for the production of renewable and clean energy. This research aims to evaluate the performance of combined variational mode decomposition (VMD) with a multi-functional recurrent fuzzy neural network (MFRFNN) and quantile regr

Konkurrensrättsligt intrång i immaterialrättsskyddat område

Abstract in Undetermined Astra- och Microsoft-fallen väntar på avgöranden i Förstainstansrätten. Bägge väcker viktiga principfrågor i skärningspunkten mellan immaterialrätt och konkurrensrätt. Astra1 har fällts av kommissionen för att företaget missbrukat sin dominerande ställning. Med tveksamma och delvis felaktiga uppgifter har Astras ”blockbuster” Losec fått ett förlängt patentskydd. Trots ins

The protonation status of compound II in myoglobin, studied by a combination of experimental data and quantum chemical calculations: Quantum refinement

Treatment of met-myoglobin (Fe-III) with H2O2 gives rise to ferryl myoglobin, which is closely related to compound II in peroxidases. Experimental studies have given conflicting results for this species. In particular, crystallographic and extended x-ray absorption fine-structure data have shown either a short (similar to170 pm) or a longer (similar to190 pm) Fe-O bond, indicating either a double

Utvärdering av olika farthinder på Malmös huvudgator

Varje år sker det tusentals olyckor i trafiken i Sverige till följd av det stora transportbehovet i samhället. Transportstyrelsen har ett mål, Nollvisionen, som innebär att ingen ska dödas eller skadas allvarligt i trafiken. För att nå målet är en åtgärd att hastigheten sänks där gång- och cykeltrafik behöver interagera med motorfordon. Det kan man göra i form av sidoförskjutningar, avsmalning av Every year, thousands of traffic accidents occur in Sweden as a result of the transportation need in society. The Swedish Transport Agency has a goal, Vision Zero, which means that no one should die or be severely injured in traffic. To reach the goal one measure is to reduce the speed where pedestrians and cyclists need to interact with motor vehicles. This can be done by chicanes, narrowing of t

Enhancing the Activity of a Dietzia sp. D5 Baeyer-Villiger Monooxygenase towards Cyclohexanone by Saturation Mutagenesis

A recombinant Baeyer-Villiger monooxygenase, BVMO4 from Dietzia sp. D5 has been previously reported. The enzyme exhibited good thermostability and was active with a wide range of cyclic ketone substrates but catalysed poorly the conversion of cyclohexanone to caprolactone. The present work focuses on protein engineering of BVMO4 to improve the conversion of cyclohexanone. Thus, a structural model

A Genetic Algorithm for Optimizing Mobile Stroke Unit Deployment

A mobile stroke unit (MSU) is an advanced ambulance equipped with specialized technology and trained healthcare personnel to provide on-site diagnosis and treatment for stroke patients. Providing efficient access to healthcare (in a viable way) requires optimizing the placement of MSUs. In this study, we propose a time-efficient method based on a genetic algorithm (GA) to find the most suitable am

Response of six European forest sites to decided and proposed air pollutant emission reductions

Two acid deposition scenarios were simulated for six European forest sites situated in Germany, Denmark, Russia, Switzerland, Spain and Ireland. Three models were used in combination; the RAINS (Regional Acidification INformations and Simulation) model, the SAFE (Simulating Acidification in Forest Ecosystems) model and the MakeDep model. The scenarios used were based on results from international

Isotherms for adsorption of cellobiohydrolase I and II from Trichoderma reesei on microcrystalline cellulose

Adsorption to microcrystalline cellulose (Avicel) of pure cellobiohydrolase I and II (CBH I and CBH II) from Trichoderma reesei has been studied. Adsorption isotherms of the enzymes were measured at 4 degrees C using CBH I and CBH II alone and in reconstituted equimolar mixtures. Several models (Langmuir, Freundlich, Temkin, Jovanovic) were tested to describe the experimental adsorption isotherms.

Samverkan och kommunikation i ett byggprojekt

Communication is a keyword to success in a construction project and whit modern-days situation with the reduced building time and a lot of stress involved is it very important that correct information reaches out to the right persons on the right time. Many different partners are involved in the building project and each one of them works towards their own goals without thinking of the integrity.

Den som dokumenterar en grop åt andra

An archaeological excavation made within contract archaeology almost invariably means that the site is destroyed. This means that the documentation, which can be seen as the site’s remaining archive, is extremely important. In this master’s thesis the written digital documentation from eight excavations made within Swedish contract archaeology between 2000 and 2013 is examined using the technique

Pollen tablets

Dear Customer,A new batch (pdf, new tab) is now ready for sale – 101023-231. Unfortunately, we need to increase the price per bottle of 250 tablets to cover the production costs.Orders of 1-4 bottles: 4 000 SEK per bottle + postageOrders of 5-9 bottles: 3 500 SEK per bottle + postageOrders of 10 or more bottles: 3000 SEK bottle + postagePostage cost depends on size and weight of the package, and h

https://www.geology.lu.se/services/pollen-tablets - 2026-06-05

Arsenic adsorption by iron-aluminium hydroxide coated onto macroporous supports: Insights from X-ray absorption spectroscopy and comparison with granular ferric hydroxides.

This paper evaluates the arsenic adsorption characteristics of a macroporous polymer coated with coprecipitated iron-aluminium hydroxides (MHCMP). The MHCMP adsorbent-composite fits best with a pseudo-second order model for As(III) and a pseudo-first order kinetic model for As(V). The MHCMP shows a maximum adsorption capacity of 82.3 and 49.6mgAs/g adsorbent for As(III) and As(V) ions respectively

Examensarbete - Framtagande av handlingsplan för geodatabas

Signal is a very important part of the railway. If you place a signal or a different object which is also important in the wrong place, can mean increased safety risks. To ease the work of the consultants in the creation of operational site drawings, the aim is to develop an action plan for the creation of a database, which in turn will be used to create a tool that can be used to automate the pro