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Background: Historically, endocrine therapy was used in a range of scenarios in patients with rising PSA, both as a treatment for locally advanced non-metastatic prostate cancer and PSA recurrence following curative intended therapy. In the present study the objective was to investigate if chemotherapy added to endocrine therapy could improve progression-free survival (PFS). Materials and Methods:
Background: [18F]PSMA-1007 is a prostate specific membrane antigen (PSMA) ligand for positron emission tomography (PET) imaging of prostate cancer. Current guidelines recommend imaging 90–120 min after injection but strong data about optimal timing is lacking. Our aim was to study whether imaging after 1 h and 2 h leads to a different number of detected lesions, with a specific focus on lesions th
•Robberies as well as mental distress have increased among adolescents in Sweden.•This study on school students in southern Sweden was population-based with a high response rate.•Half of the robbed adolescents abstained from police reporting.•Non-reporters had poorer mental health than victims who reported the robbery.•Non-reporters were also an overall more disadvantaged group.
Purpose: Patients with persistent or recurrent papillary and poorly differentiated thyroid cancer can be effectively treated with radioiodine, if the tumour tissue is iodine-avid. However, iodine-avidity status is often unknown at the time of initial radioiodine treatment, limiting any adaptive approach. This study aimed to clarify the relationship between pre-therapeutic iodine avidity in primary
Increasing tourist use of public transport is a potentially significant means of reducing greenhouse gas emissions. There are limited theoretically informed studies that focus on domestic tourist use of public transport, particularly in an Asian cultural context (e.g. South Korea). To bridge the research gap, this study applies and tests an extended value-attitude-behaviour (EVAB) theory, includin
Quality control is an essential element of manufacturing operations that reduces product defects and provides excellent products of the right specifications to the end consumer. Industry 4.0 solutions, such as digitalisation, along with lean manufacturing tools, may support quality control operations. This paper presents a case study of a food company wherein quality control checks were optimised
Antibodies play a central role in the immune defense against SARS-CoV-2. Strong evidence has shown that non-neutralizing antibodies (nnAbs) are important for anti-SARS-Cov-2 immunity through Fc-mediated effector functions. These nnAbs bind to epitopes that could be less subjected to mutations in the emerging variants. When protective, such nnAbs would constitute a more promising alternative to neu
Background: Perforator aneurysms of the basilar artery (PABA) are rare causes of subarachnoid haemorrhage (SAH) and challenging to diagnose. We present two cases of SAH caused by PABA diagnosed by cone beam computed tomography angiography (CBCTA) and a novel non-invasive method – 7T magnetic resonance imaging (7T MRI). Methods: Two patients with SAH, diagnosed with PABA, were imaged on day 9 and 1
PermissionsORIGINAL ARTICLESProtein and Amino Acid Metabolism in Three- to Twelve-Month-Old Infants Fed Human Milk or Formulas with Varying Protein ConcentrationsÅkeson, Pia M. Karlsland; Axelsson, Irene E. M.; Räihä, Niels C. R.Author InformationJournal of Pediatric Gastroenterology & Nutrition 26(3):p 297-304, March 1998.FREEAbstractBackground: The metabolic response to different protein int
Background: Leakage of fire-fighting foam from an airfield caused contamination of the drinking water supplied to a third of the population in Ronneby, resulting in very high serum levels of predominantly perfluorooctane sulfonate (PFOS) and perfluorohexane sulfonate (PFHxS). The results of studies investigating the association between exposure to perfluorinated alkyl substances (PFAS) and pregnan
Two-particle correlations with KS0 , Λ / Λ ¯ , and charged hadrons as trigger particles in the transverse momentum range 8 < pT , trig< 16 GeV/ c , and associated charged particles within 1 < pT , assoc< 8 GeV/ c , are studied at midrapidity in pp and central Pb–Pb collisions at a centre-of-mass energy per nucleon–nucleon collision sNN=5.02 TeV with the ALICE detector at the LHC. After subtracting
Titan aluminium alloys belong to the group of α–β-alloys, which are used for many applications in industry due to their advantageous mechanical properties, e.g. for laser powder bed fusion (PBF-LB) processes. However, the composition of the crystal structure and the respective magnitude of the solid fraction highly influences the material properties of titan aluminium alloys. Specifically, the the
Background:Rectal cancer patients commonly benefit from neoadjuvant therapy before resection surgery. For these patients, an elective ostomy diversion is frequently considered, despite the absence of conclusive evidence when a diversion is advantageous. This is a retrospective observational single-center study on a 4-year consecutive rectal cancer cohort undergoing neoadjuvant therapy, aiming at i
A new technique to speed up the phase separation of aqueous two-phase systems is described. The technique is based on the addition of magnetically susceptible additives (ferrofluids or iron oxide particles). In a magnetic field such additives will induce a faster phase separation. In one approach, dextran-stabilized ferrofluid was added to an aqueous two-phase system containing polyethylene glycol
OBJECTIVES: The occurrence of hand and forearm disorders related to vibration exposure, adjusted for relevant background factors, is scarcely reported. We analysed the prevalence of such conditions in a large population cohort, stratified by sex, and associations with exposure to vibrating hand-held tools.DESIGN: This is a retrospective cohort study.SETTING: Individuals in the Malmö Diet and Cance
