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Intrinsically disordered proteins are involved in many biological processes such as signaling, regulation, and recognition. A common strategy to regulate their function is through phosphorylation, as it can induce changes in conformation, dynamics, and interactions with binding partners. Although phosphorylated intrinsically disordered proteins have received increased attention in recent years, a
Melanoma in advanced stages is one of the most aggressive tumors and the deadliest of skin cancers. To date, the histopathological staging focuses on tumor thickness, and clinical staging is a major estimate of the clinical behavior of primary melanoma. Here we report on an observational study with in‐depth molecular profiling at the protein level including post-translational modifications (PTMs)
Peirce's best idea, and the one least implemented by himself and his followers, is that of an ethics of terminology. Using this ethics as a tool, we suggest that many Peircean terms are in fact misleading, or, as he said himself at the end of his life, "injurious."From the point of view of cognitive semiotics, there is no reason to abide by Peirce's definition of semiosis, but, taking up the two q
Anthropogenic pollution is a pervasive feature of urbanisation, reaching into ecosystems worldwide and posing novel challenges to wildlife. Not surprisingly, differences in behaviour, and physiology, have been found between urban and rural populations. Most studies on anthropogenic impacts have so far either used a dichotomous approach, comparing urban-rural sites, or investigated impacts of just
Children require a large amount of time, effort, and resources to raise. Physical help, financial contributions, medical care, and other types of assistance from kin and social network members allow couples to space births closer together while maintaining or increasing child survival. We examine the impact of kin availability on couples' reproductive success in the early twentieth-century United
The longitudinal motion and the intramural shear strain of the arterial wall increase dramatically in response to blood pressure, thereby impacting the vascular wall microenvironment. Exposure to a sedentary lifestyle has been identified as an independent risk factor for cardiovascular disease, but it has been shown that intermittent physical activity embedded into everyday life is enough to impro
If policy meets its intended goals or not is important in the context of energy transition. We explore if a policy, the EU Taxonomy, designed to foster green investments, meets its intent. We built an overall understanding about the EU Taxonomy by reviewing literature and EU Taxonomy documents. Additionally, we test constraints from the EU Taxonomy on CO2 emissions and on new investments in fossil
Within the field of Strategic Communication, geopolitical rivalries are increasingly understood as struggles for narratives and discursive dominance. This thesis explores a critical juncture in this landscape: the period between late 2025 and early 2026, marked by US President Donald Trump’s renewed push to acquire Greenland, stating the US would take it “one way or another”. The study examines ho
For a coating to withstand scratches, and have good abrasion resistance are extra important for some applications. PVC floors for example are often exposed to extensive wear, and it is therefore important to coat it with a coating that can withstand the hard use. One type of UV coating that have good scratch and abrasion resistance is a coating containing urethane acrylate resin. This type of re
This project evaluates the impact of interior insulation on external walls in three Swedish heritage buildings. Field measurements and hygrothermal simulations were conducted to assess available solutions. Measurements of temperature and relative humidity were taken both indoors and outdoors, as well as on the exterior and interior surfaces of the walls. The accuracy of simulation standards for in
Introduction: The evidence-base for the impact of participating in the arts for different aspects of health and wellbeing is growing. Arts on Prescription has gained increasing recognition as a method for fostering connections among individuals and communities, however, to date no systematic review of the impact on individual health and wellbeing has been conducted. This review aims to provide an
This study explores Buddhist monks’ views on the religion-science relationship in contemporary China. Drawing on survey data, interviews with monks, and participant observation within Shaolin Temple – famous for its antiquity and its export of Shaolin Kungfu – we discern and theoretically account for two forms of ‘non-conflict,’ between science and religion, that shape monks’ mental lives. One gro
The Baltic Sea has a generally low biodiversity, and several species are declining due to high anthropogenic pressure. One example is the Baltic Sea cod (Gadus morhua, L.), the cod has decreased since the 1980s in both biomass and abundance. One potential solution to increase the cod population is to improve settling ground and provide shelter for juveniles in artificial reefs. The Hanö Cod Reef p
Craft has been a steady adversary to the proliferation of industrialization. As an imaginary of embodied work, mainly driven by intrinsic motivation and by a strive for excellence, craft is increasingly re-emerging in discussions on improving current forms of work. A common theme across research on craft is its potential to address alienation as one of the main pathologies of modern work. We study
Music and Performing Arts is one of the fields Georgia can pride itself on internationally. While the country is in transition as it officially embarks on its long path to European Union membership, this study explores the process of Europeanization of higher music education in Georgia. Authors analyze how higher music educational institutions employ European projects for organizational change at
We study the impact of the early gender environment on inequality in the labor market. To this end, we link primary school data to occupations and earnings. We find that women exposed to more girls at critical ages earn more later on: A 10 percent increase in the share of girls leads to a gender wage gap reduction of 2.7 percent. We explore mechanisms and find a strong selection of women into less
We study the effect of childbirth on local and non-local employment dynamics for both men and women using Belgian social security and geo-location data. Applying an event-study design that accounts for treatment effect heterogeneity, we show that 75 percent of the effect of the birth of a first child on the overall gender gap in employment is accounted for by gender disparities in non-local employ
Popular Abstract in Swedish En stor fråga för människor, och särskilt fysiker, är hur Universum skapades. Numera känner alla till Big Bang teorin, där Universum började i en mycket våldsam händelse för fjorton miljarder år sedan. I det unga Universum (tusentals år efter Big Bang), var materien så het att elektroner och protoner inte var bundna tillsammans i atomer. Detta kallas plasma, och är matThe chain from hadron collisions to the physics results requires several important links. First the outcome of the collision is measured by the detectors. Then, the signal from the detector is processed and transformed into information relevant for the study of the physics processes. The data is made available to physicists to be analysed and used to improve theories. This thesis presents work don
