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Timetables are important for train punctuality. However, relatively little attention has been paid to the people who plan the timetables: the research has instead been more centred on how to improve timetables through simulation, optimisation, and data analysis techniques. In this study, we present an overview of the state of practice and the state of the art in timetable planning by studying the
The combined quantum mechanical (QM) and molecular mechanical (MM) approach (QM/MM) is a popular method to study reactions in biochemical macromolecules. Even if the general procedure of using QM for a small, but interesting part of the system and MM for the rest is common to all approaches, the details of the implementations vary extensively, especially the treatment of the interface between the
Understanding the relationships between snow and vegetation is important for interpretation of the responses of alpine ecosystems to climate changes. The Qinghai-Tibetan Plateau is regarded as an ideal area due to its undisturbed features with low population and relatively high snow cover. We used 500 m Moderate Resolution Imaging Spectroradiometer (MODIS) datasets during 2001–2010 to examine the
Background: Knee arthroscopy is one of the most common surgical procedures worldwide and the number of arthroscopies has substantially increased in the last 30 years. Thus, our aim was to provide updated estimates on the risk of complications and compare it with the background risk in the general population. Methods: We identified patients aged 15-84 years with knee arthroscopy in the years 2005-2
Obesity is closely associated to several diseases such as type 2 diabetes, cardiovascular disease, hepatic steatosis, airway disease, neurodegeneration, biliary diseases and certain cancers. It is, therefore, of importance to assess the role of nutrition in disease prevention as well as its effect in the course of such pathologies. In the present study, we addressed the impact of the exposure to d
PURPOSE OF REVIEW: The aim of this study was to discuss recent advances regarding the pathogenesis of transfusion-related acute lung injury (TRALI), which highlight the pathogenic role of macrophages. RECENT FINDINGS: TRALI remains a leading cause of transfusion-related fatalities, despite the success of the mitigation strategy, and therapeutic approaches are unavailable. Neutrophils (PMNs) are re
Self-assembling peptide-based hydrogels are a class of tunable soft materials that have been shown to be highly useful for a number of biomedical applications. The dynamic formation of the supramolecular fibrils that compose these materials has heretofore remained poorly characterized. A better understanding of this process would provide important insights into the behavior of these systems and co
This paper proposes a critical assessment of the jurisprudence of the Inter-American Court of Human Rights (IACRTHR) regarding the systemic integration of the provisions enshrined in the American convention on human rights (ACHR), under the light of the developments of the corpus juris of international human rights law. By incorporating the evolution in the interpretation of human rights law into
The Tibetan Plateau is the highest and largest plateau in the world, hosting unique alpine grassland and having a much higher snow cover than any other region at the same latitude, thus representing a “climate change hot-spot”. Land surface phenology characterizes the timing of vegetation seasonality at the per-pixel level using remote sensing systems. The impact of seasonal snow cover variations
Objectives Study the proportion of patients affected by involuntary childlessness who are denied fertility treatment and the reasons behind this in a publicly funded healthcare system. Design Survey study using prospectively collected information by healthcare professionals. Setting Two university-affiliated fertility clinics in Sweden. Participants Single women and couples in heterosexual and hom
BACKGROUND: Positive photopatch test reactions are classified according to the International Contact Dermatitis Group. The various reaction patterns are interpreted to represent patterns such as contact allergy, photocontact allergy, photoaugmentation, and photoinhibition. OBJECTIVE: To investigate whether there are any weaknesses in the interpretation of reaction patterns. MATERIALS & METHODS
The main aim of this work is to construct several new families of proper biharmonic functions defined on open subsets of the classical compact simple Lie groups SU(n), SO(n) and Sp(n). We work in a geometric setting which connects our study with the theory of submersive harmonic morphisms. We develop a general duality principle and use this to interpret our new examples on the Euclidean sphere S^3
We revisit the classical problem of when a given function, which is analytic in the upper half plane ℂ+, can be written as the Fourier transform of a function or distribution with support on a half axis (-∞, b], b∈ℝ.We derive slight improvements of the classical Paley-Wiener-Schwartz Theorem, as well as softer conditions for verifying membership in classical function spaces such as Hp(ℂ+).
This study shows the result of a simulation of a proposed kinetic reaction scheme of high-concentration (5000 ppm NO) and high-temperature (570–800 K) selective catalytic reduction of NO with NH3 on a commercial vanadia based catalyst at a system pressure of 2.2 bar. The simulations are performed with COMSOL Multiphysics ver. 5.1. Experimental data from a catalytic flow reactor can be nicely fitte
Anew search signature for excited leptons is explored. Excited muons are sought in the channel pp → μμ∗→ μμ jet jet, assuming both the production and decay occur via a contact interaction. The analysis is based on 20.3 fb-1 of pp collision data at a centre-of-mass energy of s = 8 TeV taken with the ATLAS detector at the large hadron collider. No evidence of excited muons is found, and limits are s
Education and wealth are positively correlated for individuals approaching retirement, but the direction of the causal relationship is ambiguous in theory and has not been identified in practice. We combine administrative data on individual total wealth with a reform expanding access to lower secondary school in Denmark in the 1950s, finding that schooling increases pension annuity claims but redu
