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Communities are becoming increasingly dependent on critical societal functions and flows, such as energy supply, transportation of goods and people, school and health care. Dependencies between these functions and flows are also increasing. These trends imply that disruptions in the functions and flows may quickly lead to large societal consequences through domino effects which may be very difficu
This paper describes regional support for art education at museums and galleries in Scania, Sweden, and its role in the overall education work undertaken at these institutions. The paper is exploratory to the extent that it describes a development in the field, and links this development to current research in the field of arts management, cultural economics and cultural policy research. Questions
PURPOSE: Leukemic stem cells (LSCs) may harbor important resistance to tyrosine kinase inhibitors in chronic myeloid leukemia (CML). We identified Philadelphia chromosome (Ph) positive CD34+CD38- bone marrow cells (here denoted LSCs) and addressed their response-predictive value in CML patients (n=48) subjected to nilotinib in the ENEST1st trial (NCT01061177).EXPERIMENTAL DESIGN: Two flow cytometr
Aim: The aim of this study was to explore and understand the complexity of ageing in relation to factors of importance for extending working life. Method: Discourse analysis of documents was used in an integrative review including 128 articles. Result: Four different conceptualisation of ageing are shown to affect older workers’ ability to extend their working life: (a) biological ageing people’s
Depending on the maximum amplitude of externally applied cyclic electric fields, ferroelectric ceramics show minor or major hysteresis. The materials also show asymmetric butterfly hysteresis in a prepoled material. Aiming at capturing these behaviour in a phenomenological constitutive model, a multi-surface modelling approach for ferroelectrics is introduced. In this paper, with the note on the m
Pneumococcal surface protein A (PspA) can elicit protection against Streptococcus pneumoniae in mouse infection models. PspA is classified by serology and amino acid sequence into two major families that are divided by sequence into five clades. The most variable portion of the molecule is the alpha-helical domain, which comprises the N-terminal half of PspA. Prior studies of a family 1 PspA prote
Studies have causally linked external thyroid radiation exposure in childhood with thyroid cancer. In 1995, investigators conducted relative risk analyses of pooled data from seven epidemiologic studies. Doses were mostly 50 Gy. We pooled data from 12 studies of thyroid cancer patients who were exposed to radiation in childhood (ages
Photoisomerization of 1,1′-diethyl-2,2′-carbocyanine iodide (pinacyanol) in alcohols was investigated by means of femtosecond time-resolved absorption spectroscopy. Only one out of two possible types of photoisomer was found. Viscosity-dependent kinetics indicate that the excited state dynamics consist of two parts, associated with a barrier-crossing observed in the blue side of stimulated emissio
An increased interest for separate collection of household food waste in Sweden has led to development of a number of different collection-systems - each with their particular benefits and drawbacks. In the present study, two systems for collection of food waste in households were compared; (a) use of food waste disposers (FWD) in kitchen sinks and (b) collection of food waste in paper bags for fu
Telomeres are protective cap structures at the ends of the linear eukaryotic chromosomes, which provide stability to the genome by shielding from degradation and chromosome fusions. The cap consists of telomere-specific proteins binding to the respective single- and double-stranded parts of the telomeric sequence. In addition to the nucleation of the chromatin structure the telomere-binding protei
Background & Aims: BCAT1 initiates the catabolism of branched-chain amino acids. Here, we investigated the function of BCAT1 and its transcriptional regulatory mechanism in hepatocellular carcinoma (HCC). Methods: RNASeq was used to evaluate BCAT1 mRNA levels in HCC and normal matched specimens. After the exogenous expression of BCAT1 in BEL-7404 cells and the suppression of endogenous BCAT1 e
Den globala jordbruksproduktionen har de senaste fem decennierna nästan tredubblats. Produktionsökningen beror på ett allt intensivare jordbruk samt konvertering av naturliga ekosystem till jordbruksmark. Intensifieringen av jordbruket har skett genom ökad användning av högavkastande grödor, mekanisering, bevattning, konstgödsel och bekämpningsmedel. Både intensivare jordbruk och expansionen av joGlobal agricultural production almost tripled within the last five decades. The production increase wasbased on expanding cropland and pastures, as well as the intensification of agriculture, including increased use ofhigh yielding crop varieties, machinery, irrigation, artificial fertilisers, and pesticides. Both, agriculturalintensification and the expansion of agricultural land-use lead to envi
