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The interaction between cystatin C variants, in which the evolutionarily conserved Gly-11 residue was substituted by Ala, Glu or Trp, and the cysteine proteinases, papain, ficin, actinidin and cathepsin B, was characterized. The substitutions reduced the affinity of binding in a manner consistent with the Gly residue of the wild-type inhibitor, allowing the N-terminal region to adopt a conformatio

I april 2017, blev Rebecca Tuvel, en av författarna till den feministiska filosofiskriften Hypatia, kritiserad för en artikel som hon hade skrivit och som hade publicerats av den akademiska tidskriften. Artikeln som Tuvel skrev, innefattade ett jämförande av Rachel Dolezal, en vit kvinna som identifierade sig som svart, med det av Caitlyn Jenner, en trans kvinna. Detta i sin tur ledde till att för

Master’s Programme in Asian Studies 2020-2022 | STUDENT INFORMATION 2 Programme information............................................................. 3 Studying at the Centre............................................................... 4 Location ...................................................................................... 4 Student enrolment..........................................

https://www.ace.lu.se/sites/ace.lu.se/files/info_folder_2020_06.pdf - 2026-07-18

This study aimed to explore how social workers reason about the child’s best interests in investigations concerning visitation rights when there is a risk of domestic violence. Using evaluative argumentation analysis, we examined six child welfare investigations to identify the key factors that influence decision-making. Our findings indicate that several considerations are crucial in the assessme

The focus of this work is to characterize the mechanical stresses and fatigue along the enameled wire due to thermal expansion. The stresses and fatigue is estimated for a single wire and as a function of evenly distributed temperature. The estimation is based on both analytical equations and 3D Finite Element (FE) model. This characterization of mechanical stresses and fatigue is then used to exa

Background In the coming half-century, the population of old people will increase, especially in the oldest age groups. Therefore, the prevalence of multiple chronic conditions, and consequently, the need of health care including care in hospital, is rising. Materials and methods This article includes results from three mainly qualitative articles (interviews with frail old people, physicians, and

Autoxidation of SO2(aq) in the presence of manganese(II) is one of the important pathways for sulfuric acid formation in atmospheric clouds and fogs. Recent experimental results indicating that the catalyzed reaction takes place via a complex free-radical mechanism are discussed. Previous literature is reviewed in the light of this mechanism. Under atmospheric conditions of low total concentrationAutoxidation of SO2(aq) in the presence of manganese(II) is one of the important pathways for sulfuric acid formation in atmospheric clouds and fogs. Recent experimental results indicating that the catalyzed reaction takes place via a complex free-radical mechanism are discussed. Previous literature is reviewed in the light of this mechanism. Under atmospheric conditions of low total concentration

Objectives: To analyse the section of Disclosure UK that pertains to healthcare professionals (HCPs) in order to provide insight into the database’s structure and content and suggest ways to improve its transparency.Design and participants; Cohort study of drug companies and HCPs in the 2015 and 2016 versions of Disclosure UK.Results: Companies report transfers of value (ToVs) to named HCPs or, wh

In order to identify agonist- and antagonist-binding epitopes in the human B1 and B2 bradykinin (BK) receptors, we exploited the ability of these receptors to discriminate between peptide ligands that differ only by the absence (B1) grid presence (B2) of a C-terminal Arg. This was done by constructing chimeric proteins in which specific domains were exchanged between these receptors as recently de

Cell culturing methods are increasingly used to reduce and replace the use of live animals in biomedical research and chemical toxicity testing. Although live animals are avoided when using cell culturing methods, they often contain animal-derived components of which one of the most commonly used is foetal bovine serum (FBS). FBS is added to cell culture media among other supplements to support ce

Substantial variability exists in what pathologists consider as pT4a in colorectal cancer when tumor cells are within 1 mm of the free peritoneal surface. This study aimed to determine if the measured sub-millimeter distance between tumor cells and the free peritoneal surface would offer an objective means of stratifying patients according to the risk of developing peritoneal metastases. Histologi

In this written study, I have researched video game music from the 90’s and early 2000’s to see what I can learn from the process of composing music for video games, as well as how the hardware and software capabilities of the game consoles shaped the music. First it presents my own background and relation to the subject, next it establishes what functionally separates video game music from conven

The literary heroic ideal changed with the Great War, as the Victorian hero ideal was no longer plausible in a post-war world. The new ideal was pacifist and non-heroic but not everyone who had been through the Great War agreed that there was no heroicism. This essay discusses the development of the heroic ideal in the mid twentieth century in relation to the two brothers Boromir and Faramir in J.

Living statues and artificial humans have a long cultural history. They are awe-inspiring because they are entangled with existentialist questions about reality, especially as regards the uncertainty of being. This article explores how humanoid material culture in its different forms was involved in the interaction between myriad human and non-human entities in seventeenth-century Sweden and in th

Corporate complicity in international crimes falls under the broader category of state-corporate crime, which encompasses the intersection between state and corporate misconduct. The concept of 'corporate complicity' includes both civil and criminal liability and involves various forms of involvement (e.g., direct participation, assistance, facilitation, benefiting, silent approval) and motivation

Voting cohesion in the European Parliament is a thoroughly studied field, however a deep dive into the kingmaker of coalition building, the liberal party group, has yet to be done. This thesis attempts to illustrate how voting cohesion varies within the Alliance of Liberals & Democrats and Renew Europe respectively, and what factors can explain variation in cohesion. Specifically, how cohesion