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Fluorescently-labelled variants of poly(styrene-co-maleic acid), SMA, have been synthesised by RAFT copolymerisation. We show that low ratios of vinyl fluorophores, analogous to styrene, can be successfully incorporated during polymerisation without detriment to nanodisc formation upon interaction with lipids. These novel copolymers are capable of encapuslating lipids and the model membrane protei
Peatlands have acted as net CO2 sinks over millennia, exerting a global climate cooling effect. Rapid warming at northern latitudes, where peatlands are abundant, can disturb their CO2 sink function. Here we show that sensitivity of peatland net CO2 exchange to warming changes in sign and magnitude across seasons, resulting in complex net CO2 sink responses. We use multiannual net CO2 exchange obs
This review presents state-of-the-art knowledge and identifies knowledge gaps for future research in the area of exercise-associated modifications of infection susceptibility. Regular moderate-intensity exercise is believed to have beneficial effects on immune health through lowering inflammation intensity and reducing susceptibility to respiratory infections. However, strenuous exercise, as perfo
A major radiological or nuclear emergency may, apart from causing a substantial loss of life and physical damage, also put a substantial strain on affected societies with social, economic and political consequences. Although such emergencies are relatively uncommon, it is now being increasingly recognised that their subsequent psychosocial impact can be widespread and long lasting. Mental health e
Our chapter engages with language transfer in SLA with particular focus on the area of grammar. We argue that transfer only plays a minor role in the acquisition of grammatical structures. In order to support our claim, we present data from studies with early and intermediate learners of English.
Author of Biographia Literaria (1817) and The Friend (1809-10, 1812 and 1818), Samuel Taylor Coleridge was the central figure in the British transmission of German idealism in the 19th century. The advent of Immanuel Kant in Coleridge’s thought is traditionally seen as the start of the poet’s turn towards an internalized Romanticism. Demonstrating that Coleridge’s discovery of Kant came at an earl
IntroductionAn important hallmark of cancer is escaping the immune system. Despite advances in immunotherapy, only a subset of patients experiences clinical benefits. It was shown that adoptive T cell or checkpoint inhibition therapy rely on the presence of conventional dendritic cells type 1 (cDC1). cDC1 excel in recruiting and priming protective CD8+ T cells through cross-presentation. However,
Plant development is regulated by transcription factors that often act in more than one process and stage of development. Yet the molecular mechanisms that govern the functional diversity and specificity of these proteins remains far from understood. Flower development provides an ideal context to study these mechanisms since the development of distinct floral organs depends on similar but distinc
Currently, there is a need for diagnostic markers in Lewy body disorders (LBD). α-synuclein (αSyn) RT-QuIC has emerged as a promising assay to detect misfolded αSyn in clinically or neuropathologically established patients with various synucleinopathies. In this study, αSyn RT-QuIC was used to analyze lumbar CSF in a clinical cohort from the Swedish BioFINDER study and postmortem ventricular CSF i
The global food system is facing significant challenges, for example, Sweden is a big partner of the European Union in terms of imported and exported food, like many countries in the world, Sweden depends on other countries for food production. In addition to it, the agriculture industry is responsible for 26% of greenhouse gas emissions in the world, due to the transportation of food, use of land
In the dynamic realm of social media marketing, maintaining a competitive edge is crucial; hence marketers are actively seeking strategies to stand out and increase levels of engagement. The study aimed to provide valuable insights into companies' utilisation of native content advertising on TikTok and users' attitudes towards this marketing strategy. By exploring the content types that in
Poly (ADP-Ribose) Polymerase 14 (PARP14) is an ADP-ribosyltransferase, an enzyme whose catalytic activity is to transfer ADP ribose (ADPr) to a target molecule, utilizing its substrate NAD+. PARP14 has been discovered to partake in the development of different kinds of cancers such as multiple myeloma, B-cell lymphoma and sarcoma, which has led to the interest of using PARP14 as a drug target for
Background: For decades, aviation has been an important part of society and with its growth comes the increased environmental impact and the challenge to reduce this adversary effect and move towards sustainability. Objective: Find out how airlines can reduce their emissions and become more sustainable. Method: A literature review was conducted including scientific articles, data from Airbus and o
Various studies on clientelism usually start from a common puzzle: Why is campaign clientelism widely practised by politicians even when they have no means of ensuring reciprocity from the voters? Similarly, why is campaign clientelism widespread amongst voters despite its numerous negative consequences on societies, democracy, and development? These puzzles have motivated my research, where I att
There are mainly three different international legal obligations regarding child soldiers in internal armed conflicts. The prohibition from child recruitment, to provide special protection for children and protection from taking part in hostilities. All are applicable to States but it is less clear which of them apply to non-state actors. In order to determine if these obligations are applicable t
Equitable distribution of healthcare services towards the reduction of HIV-AIDS prevalence in Nigeria remains a major public health concern. One of several research model to solve this public health problem is the use Geographical Information System, a two-step floating catchment area (2SFCA), this model emerged in the last decade as a key measure of spatial accessibility, particularly in its appl
Globalisation is increasing diversity in the workplace. However, while the pools of applicants are becoming more and more diverse, diversity is often not reflected in companies' workforces. The reasons for this include a lack of diversity management, processes that are not adapted to the increasing diversity, and biases. Therefore, this research aims to develop a conceptual framework for compa
This study presents a scoping review of tools to assess psychosocial stress in humanitarian aid workers, with a particular focus on the third version of the Copenhagen Psychosocial Questionnaire (COPSOQ III), and an overview of interventions to address work-related stress in this population. The databases Lubsearch and PsycInfo were searched for journal publications reporting on the validity of th
Additiv tillverkning (AM) är vanligtvis relaterat till snabb prototypframställning, även om det nu för tiden blir ett verkligt alternativ för mindre serieproduktioner. Expansionen av denna teknik är direkt relaterad till produktionskostnaderna, men med rätt verktyg i designfasen är det möjligt att även hjälpa utvecklarna av en produkt att välja vilket som är det bästa materialet eller AM-tekniken Additive manufacturing (AM) is commonly related to rapid prototyping, although nowadays it is becoming a real option for small-batch production. The expansion of this technique is directly related with the production costs. However, with the supporting tool in the conceptual phase of design it is possible to guide the product developers at selecting the most appropriate material and AM technology
DNA barcodes carry coarse-grained genetic information of DNA sequences taken from a genome. Potential applications include bacteriology, medical diagnosis and taxonomy. However, the current state-of-the-art tools for extracting DNA molecules from cells provide only fragmented pieces of chromosomal DNA. As a consequence, also DNA barcodes are fragmented. This calls for the development of complement
