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About one in ten persons is born with, or develops, a physical, sensory or mental impairment. When this stops a person from participating in normal life, it becomes a handicap. The aim of this Building Issue is to help create physical environments, particularly in public buildings, that support people with physical and sensory impairments, so that they do not become handicapped. This report identi

Hypoglycaemia is presumed to be the cause of death in about 3% of insulin-treated diabetic patients. Some of these patients suffer from hypoglycaemic brain damage, but the majority have no evident brain damage and are supposed to have died from other causes such as a cardiac arrhythmia. The putative mechanism is a hypoglycaemia-induced prolongation of the QT interval which increases the risk of ma

Background: Activated mast cells can produce and release a number of inflammatory mediators involved in the pathophysiological process of acute conditions. The aim of the study was to evaluate the effect of mast cell stimulation on the early development of multiple organ dysfunction (MODS) in acute pancreatitis (AP). Methods: AP was induced by the intraductal infusion of 5% sodium taurodeoxycholat

BACKGROUND: Human papillomavirus types 16 (HPV-16) and 18 (HPV-18) cause approximately 70% of cervical cancers worldwide. A phase 3 trial was conducted to evaluate a quadrivalent vaccine against HPV types 6, 11, 16, and 18 (HPV-6/11/16/18) for the prevention of high-grade cervical lesions associated with HPV-16 and HPV-18. METHODS: In this randomized, double-blind trial, we assigned 12,167 women b

Pressure-sensitive paint (PSP) is used to acquire high-fidelity images of steads pressure distributions across surfaces. The PSP luminescence emission response to excitation light depends in a straightforward way on the oxygen concentration (hence air pressure) and the irradiance incident on the PSP lumiphores. Often, however, the phenomenon of interest is unsteady. During a rapid change in pressu

Background & Aims: A 30-year-old woman, treated with buserelin, an analogue of gonadotropin-releasing hormone (GnRH) (also called luteinizing hormone-releasing hormone, LH-RH), developed chronic intestinal pseudo-obstruction (CIPO). The sudden onset of this disease in a previously healthy woman perplexed us. CIPO refers to a gastrointestinal disorder that can have a variety of causes, such as

The long-term outcome of thoracic and lumbar fractures in late adolescence is sparsely described and it is unclear whether a fractured vertebral body in these years, as in young children, can be resituated in height. The purpose of this study was to in late adolescence determine the incidence, the long-term outcome and the modelling capacity in fractures of the thoracic and lumbar region. The inci

We investigate the existence of solutions to first-order ordinary differential equations that asymptotically approach a prescribed function. Conditions for existence are given that relate the equation to a similar equation for the prescribed function. (c) 2006 Elsevier Ltd. All rights reserved.

This paper presents the Malmo Breast tomosynthesis project The tomosynthesis equipment is described as well as the patient selection and image acquisition. Special fucus is given to one of the studies of the project, which is a comparison of the diagnostic performance between breast tomosynthesis (BT), digital mammography (DM) and ultrasonography (US): tumor classification according to the BIRADS

Abstract in UndeterminedMarine operations depend on the ability to forecast suddenly appearing storms, and failures often cause great damage. As part of a sea-state alarm study, meteorological forecasts overlaid with satellite observations sent to ships have been found to be a useful too]. In this paper we present a real-time assimilation algorithm that extends this tool using statistical methods.

Variable time-step methods, with general step-size control objectives, are developed within the framework of variational integrators. This is accomplished by introducing discrete transformations similar to Poincares time transformation. While gaining from adaptive time-steps, the resulting integrators preserve the structural advantages of variational integrators, i.e., they are symplectic and mome