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Maf transcription factors in beta cell function

Diabetes mellitus is metabolic disorder caused by a defect or lack of beta cell-produced insulin that controls blood glucose homeostasis. In addition to glucose, insulin secretion is regulated by the autonomic nervous system (ANS); the neurotransmitter acetylcholine as well as monoamines, such as dopamine, serotonin, melatonin and norepinephrine. Using a MafA mutant mouse model, we show that MafA

Inverse probability weighted generalised estimating equations for longitudinal data

The investigation of lung function in a population plays an important role in diagnosis and assessment of many airway diseases. In addition, an overview of the lung function status can help provide better health-care options and inform medical decisions. When studying the lung function, the collection of measurements (data) of the lung function from voluntary individuals is a crucial part. Often,Longitudinal study designs, in which variables of interest are observed at multiple time points in a study population, are frequently used in clinical research. Missing data are common in these types of studies. Moreover, in studies investigating a population where the mortality rate is high, data can be truncated by death. To handle missing or truncated data, it is important to investigate the un

Coping with Chronic Warfare : The Athenian Experience

In Classical Athens, being at war was more common than peace. The military expenditures were correspondingly large. The main puzzle, however, is not financial, but where the Athenians found the multitude of rowers needed for their ships. It was not until the end of the Peloponnesian War that there were good reasons to use slaves as rowers. The Spartan occupation of Decelea in 413 BCE had profound

The Milky Way and its Exoplanets

The detections of over 4000 exoplanets as of today has shown that they exist in a wide range of different configurations, otherwise known as architectures. Recently, studies have been made trying to link the environment of host stars to the architectures of their planetary systems and have found that the architectures of planetary systems may not necessarily be uniform in the Milky Way. Since effe

"Motherhood Means Business: a motivational factor behind entrepreneurship?” A qualitative study of what can motivate a mother to become an entrepreneur

Title: Motherhood Means Business: a motivational factor in entrepreneurship Seminar date: 1 June 2023 Course: FEKH99, Bachelor Degree Project in Entrepreneurship and Innovation Management, Business administration, 15 University Credit Points Authors: Molly Eklund, Isa Stinger & Stina Svensson Advisor: Ziad El-Awad Keywords: Mother entrepreneurship; motivational factors; Push and Pull theory; O

The multi-faced controller - A case study of how managers and controllers perceive the role of the controller within a Swedish industrial company

We have identified a number of different roles within the controller’s role itself. Two types of discrepancies were discovered. The first one, called interpretation gap shows that there is a discrepancy between the managers’ expectations on the role of the controller and the controllers’ interpretation of these expectations. The second discrepancy illustrates that there are expectation gaps occurr