Filtyp
Background & Aims Obesity, commonly assessed based on body mass index (BMI), is associated with an increased risk for severe liver disease. It is not known if other measures of body composition are better determinants of risk for severe liver disease, and/or if these differ between women and men. We investigated the body composition measures that best predict the development of severe liver di
BACKGROUND:: Exposure to second-hand smoke has been shown to be associated with increased cardiovascular mortality in several, but not all, epidemiologic studies. Our aim was to investigate the risk of circulatory death associated with exposure to second-hand smoke in never-smokers in a very large prospective study, the European Prospective Investigation into Cancer and Nutrition. A secondary aim
Cytogenetic analysis has proven to be a mandatory part of the diagnosis of myelodysplastic syndromes (MDS) as well as a major indicator for predicting clinical course and outcome. Aside from the 5q-syndrome, no specific clinico-cytogenetic entity has been reported. To determine the incidence and clinical significance of acquired abnormalities of chromosome 17 in adult primary MDS, we reviewed the
Background: Activated phosphoinositide 3-kinase δ syndrome (APDS) 2 (p110δ-activating mutations causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI]-R1), a recently described primary immunodeficiency, results from autosomal dominant mutations in PIK3R1, the gene encoding the regulatory subunit (p85α, p55α, and p50α) of class IA phosphoinositide 3-kinases. Objectives: We sought
OBJECTIVE: To compare the effects of care based on comprehensive geriatric assessment (CGA) as a complement to usual care in an outpatient setting with those of usual care alone. The assessment was performed 36 months after study inclusion.DESIGN: Randomized, controlled, assessor-blinded, single-center trial.SETTING: A geriatric ambulatory unit in a municipality in the southeast of Sweden.PARTICIP
Objectives: In Sweden, lung transplantation has been performed in patients with end-stage lung disease since 1990. We assessed survival after lung transplantation for cystic fibrosis (CF) with focus on early mortality and outcome for patients infected with certain multiresistant bacteria, considered a relative contraindication for lung transplantation. METHODS: Review of CF and transplant database
Objective: Oesophageal atresia is an congenital anomali with incidence of 1/3000-1/4500 live births. The results of reconstructive surgery has improved greatly, to 80-92% survival reported in the last two decades. The aim of this study was to determine the incidence of oesophageal atresia in Iceland and to evaluate the results of operations at the Department of Pediatric surgery at The Children's
Frågan om dödshjälp är en pågående diskussion världen över. I Sverige är assisterat självmord inte straffbart. Eutanasi är däremot förbjudet och bedöms enligt 3 kap 2 § BrB. Denna uppsats syftar till att redogöra för den rättsliga gränsdragningen mellan assisterat självmord och eutanasi samt att analysera denna gränsdragning med hjälp av legalitetsprincipen. Rättsläget presenteras med hjälp av denThe issue of mercy killing is an ongoing discussion worldwide. In Sweden, assisted suicide is not punishable. Euthanasia, on the other hand, is prohibited and judged according to chapter 3 § 2 of the Swedish penal code. This essay aims to account for the legal demarcation between assisted suicide and eutha-nasia and to analyze this demarcation with the help of the principle of legality. The legal
Att tvångsomhänderta ett barn är ett undantag från svensk inställning att vård ska ske genom frivillighet. Det är inget som görs lättvindigt och det krävs att det finns en påtaglig risk för att barnets hälsa eller utveckling annars kommer till skada. Men hur stora krav finns det i samband med vårdens avslutande, var ligger fokus när den bedömningen görs? Syftet med detta arbetet är att titta på föTo take a child into public care against the parents will is an exception from the Swedish standpoint that all care should be given on a voluntary basis. It requires that there is a noticeable risk that the child's health or development will come to harm. But what are the demands when deciding whether the care should come to an end? Where is the focus in that process? The aim of this study is
Att förstå hur vegetation reagerar på klimatförändringar är viktigt av flera skäl, inte minst eko-nomiska när det gäller träd som är betydelsefulla för skogsbruket såsom gran (Picea abies) och tall (Pinus Sylvest-ris). För att förstå detta behövs kunskap om de mekanismer som ligger bakom trädarternas respons på förändringar i deras levnadsmiljö, vilket man kan få från paleoekologisk forskning baseThe understanding of how vegetation reacts to climate changes can be considered important for many reasons, not least economical when it comes to trees that are important for forestry industry like spruce (Picea abies) and pine (Pinus Sylvestris). To understand this we need knowledge about the mechanics that lie behind these tree species’ responses to changes in their environment, which can be der
Introduction The care needs of cancer patients can vary greatly across the course of their serious illness. Despite national efforts to promote supportive care – early integrated palliative care – in Sweden, systemic barriers such as ambiguous terminology and stigma complicate this development. Region Skåne Serious Illness Database (RSSID) is being developed to collect large-cohort data for condu
”Hwart hjerta andas krig”: an analysis of the depiction of war in Skillingtryck 1770–1830. Even though modern Swedish history has been distinctively peaceful, with the country not having been at war since 1814, the Swedish prime minister Ulf Kristersson stated in January 2025 that Sweden, while not at war, is not at peace. Since conceptualizations of war have varied throughout history, this thesis
Background: Careful assessment of the reasons for discontinuation of active surveillance (AS) is required for men with prostate cancer (PCa). Objective: Using Movember's Global Action Plan Prostate Cancer Active Surveillance initiative (GAP3) database, we report on reasons for AS discontinuation. Design, setting, and participants: We compared data from 10 296 men on AS from 21 centres across 12 co
Background: Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) enables sensitive detection and staging of prostate cancer, yet its relationship with long-term survival remains unclear. This study aimed to assess whether total lesion volume (TLV) measured on [18F]PSMA-1007 PET/CT predicts overall survival (OS) in prostate cancer patients. Methods: A co
När en person avlider aktualiseras frågor om arvsrätt. Den svenska arvsrätten har ur ett historiskt perspektiv varit starkt påverkad av föreställningar om kön och familjestrukturer. Arvsreglerna är i dag könsneutrala, vilket innebär att varken en arvlåtares eller en arvtagares kön spelar roll vid fördelningen av kvarlåtenskapen. Arvsrätten påverkas dock fortfarande av kön genom den könsfokuserade
Background and aims: Previous study showed that elevated circulating hepatokine follistatin (FST) associates with an increased risk of type 2 diabetes by inducing adipose tissue insulin resistance. Here we explore further the relationships between plasma FST levels with mortality and health outcomes. Methods and results: The population-based Malmö Diet Cancer cardiovascular cohort (n = 4733, age 4
