Filtyp
Transformation projects still tend to focus on buildings that once had life. This thesis aims to work with those that were never brought to it. In today’s world, there are an increasing amount of projects that garner a lot of attention and investment quite quickly. Some of these are taken through to the design stage and into development, only for them to suddenly not be viable. Development quickl
Chronic granulomatous disease (CGD) is an inherited disorder characterized by recurrent life-threatening bacterial and fungal infections. CGD results from defective production of reactive oxygen species by phagocytes caused by mutations in genes encoding the NADPH oxidase 2 (NOX2) complex subunits. Mice with a spontaneous mutation in Ncf1, which encodes the NCF1 (p47(Phox)) subunit of NOX2, have d
The design and layout of a two stage SiGe E-band power amplifier using a stacked transformer for output power combination is presented. In EM-simulations with ADS Momentum, at E-band frequencies, the power combiner consisting of two individual single turn transformers performs significantly better than a single 2:1 transformer with two turns on the secondary side. Imbalances in the stacked transfo
The fact that 10% of female mice enter oestrus and allow mating in the middle of the day is an old observation that has been more or less forgotten. We here show that this old knowledge can be used to improve the efficacy of both embryo transfer and insemination protocols. The present technical paper shows that rapid re-arrangements of mating cages, to achieve pseudo-pregnant recipients in the mid
The study presented in this article is about the role played by imagination when national and international organisations convey the idea of a dystopian crisis involved in the real transition to a postantibiotic era. The present is an era that can be defined as a time when no new antibiotics are discovered or developed, and existing antibiotics simultaneously become less effective since bacteria d
BACKGROUND: Research involving multimorbid older patients is gaining momentum. However, little is known about how to plan a randomised controlled trial (RCT) involving this group of patients. An evidence-based approach to the challenges of a recruitment process could guide researchers and help prevent underpowered trials.AIM: To define the number of multimorbid older patients that need to be ident
Red Cell Distribution Width (RDW) could be a risk factor for developing various chronic diseases, and seems to be a prognostic marker in patients with cardiovascular disease (CVD) or cancer. Our aim was to explore the association between RDW and all-cause and cause-specific mortality in a general population. RDW was measured in 27,063 participants (aged 45-73 years) from the population-based Malmö
Objective. Involvement of the gastrointestinal (GI) tract is a rare complication of granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). The aim was to describe frequency, diagnosis, treatment, and outcome of GI disease in a large series of patients in a single center. Methods.A database that includes all patients with GPA and MPA diagnosed since 1997 in a defined area of sou
Objectives: Patients with novel coronavirus disease 2019 (COVID-19) can present with gastrointestinal symptoms as their initial symptoms or as the main manifestations during disease progression, but the clinical characteristics of these patients are still unknown. Methods: We identified COVID-19 patients who admitted to Xiangyang No. 1 People's Hospital and presented with gastrointestinal symptoms
Background and purpose Positron emission tomography (PET) provides quantitative metabolic information and potential biomarkers of treatment outcome. We aimed to determine the prognostic value of early 18F-fluoroethyl-tyrosine (18F-FET) PET scans acquired during re-irradiation for recurrent high-grade glioma (HGG). Material and methods A phase I clinical trial of re-irradiation of HGG was carried o
Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proport
Background Breathlessness is prevalent in the general population and may be associated with adverse health outcomes. This study aimed to evaluate the association of breathlessness with Chronic Obstructive Pulmonary Disease (COPD) events, cardiac events and all-cause mortality from middle-age throughout life. Methods Breathlessness was measured in 699, 55-year old men residing in Malmö, Sweden usin
Popular Abstract in Swedish Att avstå från och att avbryta livsuppehållande behandlingar på intensivvårdsavdelningar. I mitten på 1980-talet träffade jag en 16-årig flicka, som jag kallar för Annie, som patient på en intensivvårdsavdelning. Annie var förlamad på grund av en förlossningsskada. Hon hade inte tidigare behövt sjukhusvård. Nu behövde respiratorhjälp på grund av en lunginflammation. TrMany deaths in intensive care units are preceded by decisions to withhold or withdraw life-sustaining treatment. Under what conditions are forgoing life-sustaining treatment considered appropiate, when is it optitional and when is it wrong? Relevant guidelines are essential to help medical decisionmakers, but they cannot be established only from medical knowledge. They also must be related to basi
Popular Abstract in Swedish Hjärt-lungräddning (HLR) introducerades 1960 och fick genast stor betydelse vid be-handlingen av hjärtinfarkt. Så småningom kom metoden att användas vid nästan alla till-fällen då hjärtat stannade. I mitten av 70-talet började man i USA utfärda ordinationer till sjuksköterskorna att HLR inte skulle startas på vissa patienter i händelse av att hjärtat skulle stanna. DettThe purpose was to describe ethical aspects on how do-not-resuscitate (DNR) deci-sions are made, established, and communicated between physicians, nurses, patients and relatives. A random sample of 220 physicians and nurses answered a questionnaire about their attitudes to and experiences of the making and communication of a DNR decision. The re-sponse rate was 73%. Twenty seriously ill patients,
Purpose: This study aims to examine the price transmission among ADRs (American Depositary Receipts) and their underlying shares, US market index and Hong Kong market index. We will attempt to capture how a shock in the home market is transmitted to the foreign (and vice versa). In addition we will attempt to assess the relative weight of each variable in the system generating unexpected variation
Syftet med detta arbete är att undersöka diskussionen kring testamentsregister i Sverige. Den deskriptiva delen av arbetet inriktar sig främst på varför Sverige saknar ett nationellt testamentsregister och vilka argument som har framförts för och emot ett sådant. För att ytterligare belysa frågan behandlas rättsläget för testamentsregister i Danmark och Norge som båda har någon form av testamentsrThe aim of this thesis is to discuss if registration of wills in Sweden would be possible. The descriptive part focuses mainly on why Sweden does not have a national register of wills and the arguments put forward for and against such a register. To further highlight the issue the register of wills in Denmark and Norway will be dealt with. Both of these countries have different forms of testamenta
