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Mot smartare cellgiftsbehandling: Att förebygga behandlingsresistens vid äggstockscancer Äggstockscancer är den dödligaste gynekologiska cancertypen och kräver alltför många liv eftersom tumörer ofta blir resistenta mot behandling – särskilt mot cisplatin, vårt främsta försvar. För att rädda fler liv måste vi förstå hur denna resistens utvecklas och hur vi kan överlista den. I mitt examensarbete Ovarian cancer is the deadliest gynaecologic malignancy, with most patients diagnosed at an advanced stage and facing poor long-term survival. Resistance to cisplatin-based chemotherapy is a major clinical obstacle, yet its proteomic drivers remain poorly defined. In this study, I applied data-independent acquisition mass spectrometry with DIA-NN data processing to analyse one parental and two cis

https://www.it.lu.se/sites/it.lu.se/files/programformedling_lathund_ftp.pdf - 2026-05-14

Senior lecturer Contact details Email: faustine [dot] perrin [at] ekh [dot] lu [dot] se Phone: +46 46 222 04 65Organisation Department of Economic History Visiting address: Scheelevägen 15 B, Lund Room number: Alfa 1:2087 Service point: 10 WebpageFaustine Perrins profile in Lund University research portalOther affiliations Senior lecturer Economic demography Senior lecturer Historical labour marke

https://www.lusem.lu.se/faustine-perrin - 2026-05-13

https://www.lumes.lu.se/sites/lumes.lu.se/files/lumes_programme_agenda_2020-2022_200507.pdf - 2026-05-14

BACKGROUND: Effector functions of IgG antibodies (Abs) are regulated by their Fc N-glycosylation pattern. IgG Fc glycans that lack galactose and terminal sialic acid residues correlate with the severity of inflammatory (auto)immune disorders and have also been linked to the protection against viral infection and discussed in the context of vaccine-induced protection. In contrast, sialylated IgG Ab

Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s

Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr

The aim of this thesis is to explore what impacts the IDF’s Military Orders regarding water have on Palestinians in the West Bank, taking international humanitarian law (IHL) and International Convention on Civil and Political Rights (ICCPR) into consideration. Thus, to discover whether or not Israel’s actions are compatible with IHL and treats everyone equal before the law, as stated in ICCPR Art

Bilaga 2: progressionsplan Institutionen för Naturgeografi och Ekosystemvetenskap Progressionsplan för naturvetenskaplig masterexamen, huvudområde naturgeografi och ekosystemvetenskap En generell examen ska uppfylla de nationella examensmålen och ha en successiv, poängangiven fördjupning inom huvudområdet, inklusive ett examensarbete. I denna progressionsplan för en naturvetenskaplig masterexamen

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2023-12/Progressionsplan%20naturvetenskaplig%20masterexamen%20huvudomra%CC%8Ade%20naturgeografi%20och%20ekosystemvetenskap%20rev%20230525%20ny.pdf - 2026-05-14