Filtyp
To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc
In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha
The Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
Abstract in French Cette contribution décrit l’aide potentielle que le concept de table interactive apporte à certaines tâches du concepteur en mécanique. Le travail de recherche présenté n’en est qu’à sa genèse. La problématique est la suivante : une fois la faisabilité d’une idée de produit (le concept) est prouvée, le concepteur développe l’architecture et les composants du produit (embodiment This paper describes the potential help that the interactive desktop concept can bring to the execution of embodiment design tasks. The presented project is still in its infancy. The research framework is the following: once a product concept has been approved, the mechanical design engineer develops the product architecture and product part (also called embodiment design). Sketches at that level
Je connais deux filles, elles s'appellent Thea et Bea. Elle sont les meilleurs amis. Thea est mince avec des cheveux marron et Bea est grosse avec des cheveux blondes. Une jour Thea et Bea ont decidé de faire un voyage en Italie, Thea qui est folle des garcons a rêvé des italiens, avec ses cheveux noir est ses sourires elegantes. Bea a un peau blanc et voulait se bronzer dans la plage. Mais bien s
https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_d/Dagmar.txt - 2026-07-04
Je connais deux filles, elles s'appellent Thea et Bea. Elle sont les meilleurs amis. Thea est mince avec des cheveux marron et Bea est grosse avec des cheveux blondes. Une jour Thea et Bea ont decidé de faire un voyage en Italie. Thea qui est folle des garcons a rêvé des italiens, avec ses cheveux noir est ses sourires elegantes. Bea a un peau blanc et voulait se bronzer dans la plage. Mais bien s
https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_longitudinal/dagmar/Texte_3.txt - 2026-07-04
In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses
Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat
Massive Multiple-Input Multiple-Output (MIMO) communication systems are being investigated intensively for positioning services. Enhancing the accuracy on these services in terms of accurate positioning of users is an important goal to improve related applications in the future. Convolutional Neural Networks (CNNs) has been proposed to infer the position of a user from Channel State Information (C
We introduce rigorous theory for deriving first and second order backpropagation methods for Deep Neural Networks (DNN) whilst satisfying existing theory in DNN optimization. We begin by formally defining a neural network with its respective components and state the first and second order chain rule with respect to its partial derivatives. The partial derivatives in the chain rule formula are rela
Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei
Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer velocity, kCC (introduced by Cole and Caraco, 1998), for calculating diffusive flux with the boundary layer method (BLM). We compared CH4 and CO2 fluxes from BLM wit
Using spatially explicit process- based modelling to quantify wild bee dynamics and their pollination services Johanna Häusslera,b,c*, Ullrika Sahlinc, Charlotte Baeyc, Henrik G. Smithc,d and Yann Cloughc a German Centre for Integrative Biodiversity Research (iDiv) Halle- Jena-Leipzig, Deutscher Platz 5e, 04103 Leipzig, Germany b Institute of Ecology, Friedrich Schiller University Jena, Domburger-
https://www.cec.lu.se/sites/cec.lu.se/files/posterleipzig_haeussler.pdf - 2026-07-06
The integrin CD103 and the chemokine receptor CCR9 are co-expressed on small intestinal CD8+ intraepithelial lymphocytes (IEL), naïve murine CD8+ T cells and by a small population of effector/memory CD8+ T cells, indicating a potential role for CCR9 in regulating CD103 expression and function. Here, we demonstrate that CD103, in contrast to CCR9, is down-regulated on CD8+ T cells following their a
Uppsatsen har undersökt huruvida spelföretaget Star Stable Entertainment AB marknadsföring av virtuella valutor och produkter till barn bryter mot EU:s konsumentskyddslagstiftning i ljuset av Sveriges Konsumenters anmälan mot företaget. Uppsatsen har även diskuterat om direktivet om otillbörliga affärs-metoder är anpassat för den digitala miljön med hänsyn till kommissionens aktuella fitness checkThe essay analyses whether the gaming company Star Stable Entertainment AB´s marketing of virtual currencies and other virtual products against chil-dren violates EU consumer law, considering the Swedish Consumers Associ-ation’s complaint against the company. The paper also discusses whether the Unfair Commercial Practice Directive (UCPD) is fit for the digital environ-ment, given the European Com
