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Accelerating aqueous electrolyte design with automated full-cell battery experimentation and Bayesian optimization
Reducing uncertainty : Care users’ experiences of waiting when receiving video visits from digital home care
Home care has been associated with time pressure and extensive waiting times, affecting care users’ ability to manage their daily activities. In 2023, one Swedish municipality started offering ‘video visits’ to complement home visits. However, little is known about the implications of this type of digital technology for care users’ waiting experiences. This article aims to understand how care user
Närståendes tillfredsställelse med vården på en intensivvårdsavdelning
Public defence of doctoral dissertation in Business Administration: João Maria Apolinário Jorge
Impact of emergency computed tomography on treatment and time to treatment for renal colic
Objective: The aim of this study was to evaluate the utilization and impact of emergency computed tomography (CT) on the management of renal colic, focusing on treatment decisions, time to treatment and the subsequent need for additional emergency department (ED) visits.Materials and methods: Retrospective analysis of patient visits to the ED in Helsingborg with a diagnosis of urolithiasis (ICD co
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Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin
Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel
Countercurrent Distribution of Lymphocytes from Human Peripheral Blood in an Aqueous Two-Phase System : I. Separation into Subsets of Lymphocytes Bearing Distinctive Markers’
Lymphocytes from human peripheral blood have been separated by countercurrent distribution in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000 with a cell yield of 59–88% and viability above 90%. A highly reproducible partition pattern was seen with four distinct peaks. Lymphocytes with surface membrane immunoglobulin (SmIg) were located in the first part o
Checklista Gästforskare 2026
Sociologiska inst i tut ionen Prefekt 2026-03-01 P 2026/P Diarienummer: P 2026/1626 Checklista för värdar för gästforskare och gästdoktorander Vi är glada för att ta emot gästforskare hos oss. För att det ska fungera bra både för gäster och oss på institutionen, har vi har tagit fram denna checklista för värdar. För dig som ska vara värd för en gästforskare gäller följande: Mellan 7 månader och 2
Från förening till företag - Sportslig kontra ekonomisk framgång
Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser
Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics
Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de
Antibody-dependent allostery of the M1 protein
Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities
In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha
Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis
To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc
Purification of streptococcal protein G expressed by Escherichia coli by high performance liquid affinity chromatography using immobilized immunoglobulin G and albumin
A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz
Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures
Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We
