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Multitask Convolutional Neural Network Emulators for Global Crop Models - Supervised Deep Learning in Large Hypercubes of Non-IID Data

The aim of this thesis is to establish whether a neural network (NN) can be used for emulation of simulated global crop production - retrieved from the computationally demanding dynamic global vegetation model (DGVM) Lund-Potsdam-Jena General Ecosystem Simulator (LPJ-GUESS). It has been devoted to elaboration with various types of neural network architectures: Branched NNs capable of processing in

IL1RAP Blockade with a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis

BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie

Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis

Background: Anti-neutrophil cytoplasmic antibodies associated vasculitides (AAV) are characterized by autoimmune small vessel inflammation. Eosinophils are multifunctional cells with both pro-inflammatory and immunoregulatory properties. Tissue activated eosinophils secrete cyto- and chemokines and form extracellular traps (EETs), they release free granules and produce reactive oxygen species. The

Circulating Human Basophils and Dendritic Cell Subsets. Aspects of antigen recognition and presentation in type I allergic immune responses

Popular Abstract in Swedish En tredjedel av befolkningen i världens industrialiserade länder lider av allergi, t.ex. allergisk rinit (hösnuva). Trots detta vet man relativt lite om de cellulära och molekylära mekanismer som ligger till grund för det immunologiska svaret vid allergi. Genom att studera dessa mekanismer kan man hitta sätt att angripa dem, vilket förhoppningsvis kan leda till bättre lAllergic diseases currently affect a third of the population in the industrialized parts of the world. Despite this, the cellular and molecular mechanisms involved in the induction and activation of allergic diseases are not fully clarified. Dendritic cells (DCs) link the innate and adaptive immunity and play vital roles in protective immunity against pathogens, as well as in inducing tolerance t

Studies of bacterial surface proteins interacting with the immune system

Popular Abstract in Swedish En av de viktigaste substanserna i vår kropp är proteiner, också kallade äggviteämnen. Proteiner har en mängd olika uppgifter i kroppen, de finns i våra celler där de har olika uppgifter såsom att fungera som enzymer, transportörer, signalsubstanser, eller som skyddsfaktorer. Proteiner ingår också som viktiga beståndsdelar i vävnaderna mellan cellerna och finns dessutomPathogenic bacteria express a wide array of surface proteins that interact with the environment. Many of these proteins are believed to be important for the virulence. This thesis deals with the binding of immunoglobulins (Ig) and complement regulating proteins to certain bacterial surface proteins. Protein L from Peptostreptococcus magnus binds to Igk-light chains while protein A from Staphylococ

Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo.

Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediated depletion of regulatory T cells (Tregs) in the tumor microenvironment plays a key role in efficaci

Across landscapes and seascapes : The movement ecology of diving and flying guillemots and gulls during breeding

Some seabirds we encounter only fleetingly, as they fly by as we walk along the beach, or perhaps meet far out at sea when we take a boat trip. Others though we are more familiar with, such as the ‘seagulls’ that many will not even turn their head to appreciate. Yet, all seabirds have remarkable stories to tell, and we are fortunate now to live at a time where we can follow individual birds as theMost seabirds breed colonially, at which time they make central-place foraging trips. Parents must collect food both for themselves and for egg production/chick-rearing. How should they forage? I followed five species across two sites in Sweden in the Baltic Sea using GPS and time-depth recorder (TDR) devices, giving information on both flight and diving activity. I use a movement ecology approach

Ökad olycksrisk på grund av tidsmässiga och ekonomiska faktorer inom byggbranschen?

Due to the increasing pressure of time and economical factors in the society, and the fact that construction workers are highly represented in the work accident, it is interesting to study how time and economic factors influence worker in different levels in the construction business. This report provides results from a several studies (literature study, interview study, study of accidents reports

Verksamhetsberättelse 2020 För EBSCO Systems Nordic User Group

Verksamhetsberättelse 2020 för EBSCO Systems Nordic User Group Verksamhetsåret 2020 präglades i stort av en global coronaviruspandemi med anledningen av spridningen av SARS-CoV-2 (se mer här: https://sv.wikipedia.org/wiki/Coronaviruspandemin_2019%E2%80%932021). Pandemin innebar för verksamheten att inga fysiska träffar kunde hållas under året. Därför anordnade föreningen endast digitala möten och

https://www.ub.lu.se/sites/ub.lu.se/files/2021-04/Verksamhetsber%C3%A4ttelse%202020%20f%C3%B6r%20EBSCO%20Systems%20Nordic%20User%20Group.pdf - 2026-05-02

Verksamhetsberattelse 2017 for eds nordic user group

Bilaga 1 Verksamhetsberättelse 2017 för EDS Nordic User Group Vid EDS Nordic User Groups årsmöte 2017-03-22 i Luleå valdes följande styrelsemedlemmar: ordförande Cilla Öhnfeldt, Stockholms universitet (omval), Per Falk, Högskolan i Gävle (nyval), Ann- Christin Persson, Lunds universitet (nyval), Tove Andersson, Region Skåne (nyval), Mikael Arvidsson, Karlstads universitet (omval) och Eva Sejmyr, L

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2017_for_eds_nordic_user_group.pdf - 2026-05-02

Vividness, narrative transportation, and sense of presence in destination marketing : empirical evidence from augmented reality tourism

The rise of augmented reality (AR) technology offers potential opportunities for the tourism industry and academia. Drawing upon narrative transportation and presence theory, this paper investigates the relationship between vividness, narrative transportation, sense of presence, and visiting other AR destination. The empirical findings indicate that vividness enhances narrative transportation and

High dependency of chilli fruit set on wild pollinators in southern India

Ongoing pollinator declines threaten the production of many entomophilous crops. Recent reports that yields of animal-pollinated crops in India are increasing less than pollinator-independent ones suggest the occurrence of pollen limitation. We experimentally evaluated if production of the common food crop chilli benefits from insect pollination and if crop production is constrained by lack of pol

"Vem ska ansvara för det här?" - En internkomparativ uppsats om värdekedjor i EU-rätten

Inom ekonomin har begreppet värdekedja funnits sedan 1985 då det myntades av Michael E. Porter, professor vid Harvard Business School. Porter använde värdekedjekonstruktionen för att förklara värdeskapande aktiviteter inom företag där varje aktivitet utgör en viktig länk i en större kedja som skapar värde och konkurrensfördelar för företagen. Genom att ha översikt över sin värdekedja kan varje för

International Legal Aspects of Punitive House Demolitions in the Occupied Palestinian Territories

Throughout five chapters, the thesis deals with the issues of international humanitarian and human rights law arising out of the practice of punitive house demolition, that is repetitively utilized in the Occupied Palestinian Territories by the Israeli authorities, in response to the acts of insurgency/terrorism. The first chapter (Introduction) enables the reader to get a glimpse of the precise o