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Introduction: Population-based registers provide an important source of real-world data. The growing number of large cohort studies using data from cancer registers makes validation of such registers important. The Swedish Quality Register of Gynecologic Cancer (SQRGC) is a nationwide population-based register containing data on patient and tumor characteristics, treatment, and follow-up. To ensur

A combination of searches for singly and doubly charged Higgs bosons, H± and H±±, produced via vector-boson fusion is performed using 140 fb−1 of proton–proton collisions at a centre-of-mass energy of 13 TeV, collected with the ATLAS detector during Run 2 of the Large Hadron Collider. Searches targeting decays to massive vector bosons in leptonic final states (electrons or muons) are considered. N

Structural design and risk management typically involve uncertainties related to structural performance and loading conditions, which must be effectively managed to ensure compliance with safety requirements. Additionally, the relationships among parameters influencing structural performance are often complex and not easily discernible, thereby complicating the decision-making process. To address

Accurate evapotranspiration (ET) estimation is vital for hydrological modeling, yet remotely sensed ET (RS-ET) products are often limited by algorithmic uncertainties and sensor biases. To mitigate error propagation and better capture spatial patterns, this study introduces the Composite Efficiency of Absolute ET and Spatial Autocorrelation (CEASA) —a dual-constraint framework that integrates abso

BACKGROUND: Each year, more than 1.5 million people in Europe have a stroke, and many experience disabilities leading to activity and participation restrictions. Home-based rehabilitation is the recommended approach for stroke rehabilitation, in line with the international shift to integrated care. Despite this, rehabilitation often focuses on the person's physical functions, not the whole life si

Background: People with Intellectual disabilities (ID) have more healthcare utilization, especially unplanned inpatient care. One reason could be too early hospital discharges, resulting in readmissions. This is an important aspect of quality of care that has not been thoroughly assessed among people with ID. Aim: To investigate readmission to hospital within 30 days among people with ID compared

Pulmonary arterial hypertension (PAH) is a rare disease that affects the pulmonary vasculature. Characterized by increased pulmonary arterial pressures and vascular resistance, it causes right heart failure (HF), and premature death. The main symptom, exertional dyspnoea, is non-specific where patient’s and doctor’s delay often lead to diagnosis in advanced stages. Despite development of PAH speci

Background: Many patients with a psychotic disorder participate poorly in society. When psychotic disorders are in partial remission, feelings of paranoia, delusions of reference, social anxiety and self-stigmatization often remain at diminished severity and may lead to avoidance of places and people. Virtual reality exposure therapy (VRET) is an evidence-based treatment for several anxiety disord

Analysis of naturally occurring isotopic variations is a promising tool for investigating Zn transport and cycling in geological and biological settings. Here, we present the recently installed double-spike (DS) technique at the MAGIC laboratories at Imperial College London. The procedure improves on previous published DS methods in terms of ease of measurement and precisions obtained. The analyti

Purpose: To address key issues of low SNR and image distortions in prostate diffusion MRI (dMRI) by means of using strong gradients, single-shot spiral readouts and an expanded encoding model for image reconstruction. Methods: Diffusion-weighted spin echo imaging with EPI and spiral readouts is performed on a whole-body system equipped with strong gradients (up to 250 mT/m). An expanded encoding m

AIMS: To evaluate the efficacy and safety of oral semaglutide for type 2 diabetes mellitus (T2DM) in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).MATERIALS AND METHODS: This was a single-arm, multicentre, prospective study. Among 80 consecutive patients with MASLD and T2DM who newly received oral semaglutide, 70 completed 48-week oral semaglutide treatment as sche

Background: Small bowel neuroendocrine tumours often present with locally advanced or metastatic disease. The aim of this paper is to provide evidence-based recommendations regarding (controversial) topics in the surgical management of advanced small bowel neuroendocrine tumours. Methods: A working group of experts was formed by the European Society of Endocrine Surgeons. The group addressed 11 cl

Background: Digital work can be cognitively challenging especially for people with cognitive difficulties. New occupational therapy interventions are needed to empower these persons to self-manage challenges in digital work and everyday life. To address this need, the internet-based intervention 'Strategies for Empowering Activities in Everyday Life' (SEE 2.0) was tested.Aim: To explore and descri

Human biomonitoring (HBM) frameworks assess human exposure to hazardous chemicals. In this review, we discuss and summarize sample preparation procedures and analytical methodology for six groups of chemicals of emerging concern (CECs), namely diisocyanates, benzotriazoles, benzothiazoles, 4-methylbenzylidene camphor, isothiazolinones, fragrances, and non-phthalate plasticizers, which are increasi

Many studies have underscored the impacts of drought on ecosystems, and some researchers reported the effects of accumulated soil moisture deficit (ASMD) on light use efficiency (LUE) in grassland. However, the potential effects of ASMD on gross primary productivity (GPP) and LUE for both cropland and forest ecosystems are still not understood. This study elucidated the effects of accumulated and

https://www.isk.lu.se/sites/isk.lu.se/files/komn01_avtal_ht_2019.pdf - 2026-07-22

The purpose of this study was to investigate the potential dose reduction to the heart, left anterior descending (LAD) coronary artery and the ipsilateral lung for patients treated with tangential and locoregional radiotherapy for left-sided breast cancer with enhanced inspiration gating (EIG) compared to free breathing (FB) using the AAA algorithm. The radiobiological implication of such dose spa