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Single-step NIL of micro and nanochannels combined with optical waveguides for characterization of DNA molecules
Curriculum change is easy – agreement and implementation is not!
Protein interactions with the surface of gold nanoparticles: possible means of determining particle toxicity
On the symmetry of usage of canonical antonyms in discourse
Pushing the limits of deterministic lateral displacement devices
Bioenergy Policy and Strategies for Poland
Presens och preteritum i skönlitterär prosa
I skönlitterär prosa förekommer det strängt taget enbart tre olika temporala texttyper: narration (berättande text, relation), citat (alltså dialog) och berättarens nutid (dvs. passager där en berättare talar i egen sak), och det finns bara två finita tempus att välja emellan: presens och preteritum. Det kan tyckas som om de skönlitterära författarna har ett snävt spelrum att operera inom. Men det
Fictitious Carbon, Fictitious Change? : Environmental Implications of the Commodification of Carbon
Governments increasingly rely on the use of market instruments to tackle climate change and help decarbonize a deeply fossil fuel-dependent economy. This dissertation examines this trend as one instance of the ‘commodification of carbon’, or the process through which emission reductions are made into commodities and then traded on the market. It engages the commodification framework and related th
Identification of polymorphisms in Apolipoprotein M gene and their relationship with risk of recurrent venous thromboembolism
Apolipoprotein M (ApoM) plasma levels have been reported to be associated with risk of venous thromboembolism (VTE) recurrence. However, the role of genetic alterations in the ApoM gene in VTE recurrence remains unknown. The aim of this study was to identify genetic aberrations in ApoM gene in VTE recurrence and their role in prediction of VTE recurrence in a prospective follow-up study of 1465 VT
Epidemiology of Familial Aggregation of Venous Thromboembolism
Familial aggregation (clustering) of venous thromboembolism (VTE) is the clustering of VTE within a family. Though several genes, such as antithrombin, protein C, protein S, factor V, and prothrombin are associated with the familial clustering of VTE, these loci only partially explain the familial aggregation of VTE. The epidemiology of the familial aggregation of VTE exhibits typical characterist
Preparedness for side effects and bother in symptomatic men after radical prostatectomy in a prospective, non-randomized trial, LAPPRO
Background: Many clinicians believe that preparedness before surgery for possible post-surgery side effects reduces the level of bother experienced from urinary incontinence and decreased sexual health after surgery. There are no published studies evaluating this belief. Therefore, we aimed to study the level of preparedness before radical prostatectomy and the level of bother experienced from uri
Statistical power considerations in genotype-based recall randomized controlled trials
Randomized controlled trials (RCT) are often underpowered for validating gene-treatment interactions. Using published data from the Diabetes Prevention Program (DPP), we examined power in conventional and genotype-based recall (GBR) trials. We calculated sample size and statistical power for gene-metformin interactions (vs. placebo) using incidence rates, gene-drug interaction effect estimates and
Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice
Although it is well established that unique B-cell lineages develop through distinct regulatory mechanisms during embryonic development, much less is understood about the differences between embryonic and adult B-cell progenitor cells, likely to underpin the genetics and biology of infant and childhood PreB acute lymphoblastic leukemia (PreB-ALL), initiated by distinct leukemia-initiating transloc
Effects of a culturally adapted lifestyle intervention on cardio-metabolic outcomes : a randomized controlled trial in Iraqi immigrants to Sweden at high risk for Type 2 diabetes
Background andAims Middle-Eastern immigrants constitute a growing proportion of the Swedish population and are at high risk for Type 2 diabetes. This calls for a more proactive preventive approach for dealing with diabetes risk in this target group. The aim was to test the effect of a culturally adapted lifestyle intervention programme on changes in lifestyle habits and cardio-metabolic outcomes c
Prevalence and incidence of gout in southern Sweden from the socioeconomic perspective
Objectives To estimate the prevalence and cumulative incidence of gout in southern Sweden with respect to socioeconomic status. Methods Among residents of Skåne region in the year 2013 (total population 1.3 million), adult persons (age 18 years +) who between 1998 and 2013 received a diagnosis of gout (International Classification of Disease 10th Edition (ICD-10) code M10) by any physician were id
Expression of the TPa and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer : Clinical significance and diagnostic potential
The prostanoid thromboxane (TX)A2 plays a central role in haemostasis and is increasingly implicated in cancer progression. TXA2 signals through two T Prostanoid receptor (TP) isoforms termed TPa and TPβ, with both encoded by the TBXA2R gene. Despite exhibiting several functional and regulatory differences, the role of the individual TP isoforms in neoplastic diseases is largely unknown. This stud
New Life Old Fire Station Gåsebäck, Helsingborg
So, what does a new life for the old fire station mean? It means that it is possible for a new generation to utilize the Gåsebäck landmark and historical building. The building should be attractive for the investors, for the city, and its inhabitants. The provided opportunities for the development of the building could be considered as a temporary solution for maintaining the history of the Gåsebä
Too many calories, too few nutrients? : a systems approach to food and nutrition security in Guatemala
Obesity levels in developing countries are increasing at an alarming rate, while “old” problems such as hunger and undernutrition still persist, creating a paradoxical situation of a double burden of malnutrition. Intertwined with new sustainability challenges such as climate change and land degradation, food, health and sustainability are interconnected in a complex web of relationships, spanning
Reseavdrag och miljöpolitik
Reseavdraget – Motverkar det politiska spelet incitament som kan förbättra miljön? Reseavdraget, att vara berättigad till att dra av en del av kostnaderna som uppkommer till följd av resor till och från arbetsplatsen på skatten, har förundrat mig under flera år. Är reseavdraget rättvist utformat, belönar det ett samhällsekonomiskt olönsamt val eller kan det skapa incitament för arbetspendlare attIncome Tax-deduction for commuting expenses has been criticised and discussed for a long time without having reached any conclusions or reformations. Critical opinions in the debate are that a reformation would disfavour taxpayers living in the countryside with no options except car commuting and decreasing size of labour market regions. At the same time tax evasion is a huge problem because taxpa
