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This study describes a new method for the fixation of titanium hip stem prostheses based on interdigitation of irregularly shaped porous titanium granules onto bone tissue. The granules were distributed into the prepared femoral cavity using a vibrating tool, and the stem was vibrated and tapped into the bed of granules. In this pilot study, 5 patients were followed between 9 and 15 years. The cli

There is a need for large trials that test the clinical effectiveness of interventions in the field of perioperative medicine. Clinical outcome measures used in such trials must be robust, clearly defined and patient-relevant. Our objective was to develop standards for the use of clinical outcome measures to strengthen the methodological quality of perioperative medicine research. A literature sea

Wetlands are integral components of our natural environment since they provide many critical ecosystem services to humanity, such as water purification, climate change mitigation, flood control, and biodiversity. Although wetlands can convey resilience to some degree of changes, they might be vulnerable to climate change. Altered hydrology and rising temperatures can turn the wetland services into

Purpose: To investigate the possibility to be able to offer left sided breast cancer patients, not suitable for DIBH, an organ at risk saving treatment. Materials and Methods: Twenty patients receiving radiotherapy for left breast cancer in DIBH were enrolled in the study. Planning CT scans were acquired in the same supine treatment position in FB and DIBH. 3DCRT_DIBH plans were designed and optim

BACKGROUND: Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia.METHODS: Cancer registries participating in CONCORD

Background: To evaluate the effect of a smoking-, alcohol- or combined-cessation intervention starting shortly before surgery and lasting 6 weeks on overall complications after radical cystectomy. Secondary objectives are to examine the effect on types and grades of complications, smoking cessation and alcohol cessation, length of hospital stay, health-related quality of life and return to work or

Aims: This analysis aimed to evaluate the incidence and predictors of the need for permanent pacemaker (PPM) implantation following implantation of the repositionable and fully retrievable LOTUS Aortic Valve Replacement System. Methods and results: The prospective, single-arm, multicentre REPRISE II study with extended cohort enrolled 250 symptomatic, high surgical risk patients with severe aortic

We report on the first theoretical investigation of M-F-dependent lifetimes due to interference between a magnetic octupole transition and a hyperfine induced electric quadrupole transition. Extensive multiconfiguration Dirac-Fock calculations are used to model the hyperfine quenching of the magnetic octupole decay of 3d(9)4s D-3(3) and the state mixing between the D-3(3) and D-3(2) due to hyperfi

Speditörens roll har ständigt utvecklats till att omfatta alltfler tjänster varvid en del, främst de större speditionsfirmorna, har börjat erbjuda lösningar inom fjärdepartslogistik. I detta koncept ingår, förutom transport och lagring, även en stor grupp tjänster kallade mervärdestjänster vilka kan utföras t.ex. i lagret, på terminal eller i köparens (tredjemans) lokaler. Jag har valt att fokuser

Parkinson’s disease (PD) is a neurodegenerative disorder with toxic forms of alpha synuclein (α-syn) accumulating in the midbrain dopaminergic (DA) neurons, leading to cell death. In the first part of the study we wanted to investigate the midbrain DA population and their gene expression relative to the intracellular α-syn load. To this end, human wildtype α-syn was packaged inside custom, uniquel

It is well recognised that adolescents and young adults (AYA) with cancer have inequitable access to oncology services that provide expert cancer care and consider their unique needs. Subsequently, survival gains in this patient population have improved only modestly compared with older adults and children with cancer. In 2015, the European Society for Medical Oncology (ESMO) and the European Soci