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While there is general agreement on the necessity tomeasure glomerular filtration rate (GFR) inmany clinical situations, there is less agreement on the bestmethod to achieve this purpose. As the gold standardmethod for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtrationmarkers and protocols compete to re

A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the onl

Purpose - The purpose of this paper is to present numerical investigation of the gas/vapor bubble dynamics under the influence of an ultrasonic field to give a more comprehensive understanding of the phenomenon and present new results Design/methodology/approach - In order to formulate the mathematical model, a set of governing equations for the gas inside the bubble and the liquid surrounding it

An increasing number of patients are successfully resuscitated from cardiac arrest (CA) and subsequently treated in an intensive care unit due to unconsciousness. Approximately half of these patients will die during the first weeks postarrest, typically after a determination of a poor neurologic prognosis and a decision to withdraw life-sustaining therapy (WLST). These decisions are guided by univ

BACKGROUND: The value of CT at the time of diagnosis for patients with cutaneous head and neck melanoma clinically asymptomatic for metastatic disease is unclear.METHODS: A retrospective medical chart review was performed on 198 consecutive patients identified with primary T1b-T4b head and neck melanoma clinically asymptomatic for metastatic disease referred for sentinel lymph node biopsy procedur

Ill health in early life has a significant negative impact on school grades, grade repetition, educational level, and labormarket outcomes. However, less is known about qualitative socio-economic consequences of a health shock in childhood or adolescence. We investigate the relationship between onset of type 1 diabetes up to age 15 and the probability of choosing and completing a health-oriented p

This article presents the ancient concept of stylistic levels as a means of approaching the question of how New Testament writings were delivered in antiquity. It is argued that the levels of style affected both composition and delivery and that therefore an analysis of the remaining texts is the first step towards understanding how they were once delivered. The levels of style are presented and t

Purpose - The purpose of this paper is to present some methods to analyse and determine the performance of compact heat exchangers; show the applicability of various computational approaches and their limitations, provide examples to demonstrate the methods, and present results to highlight the opportunities and limitations of the considered methods. Design/methodology/approach - Engineering metho