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BACKGROUND: In early breast cancer, variations in local treatment that substantially affect the risk of locoregional recurrence could also affect long-term breast cancer mortality. To examine this relationship, collaborative meta-analyses were undertaken, based on individual patient data, of the relevant randomised trials that began by 1995. METHODS: Information was available on 42,000 women in 78
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Most of the common modeling approaches to premixed combustion in engineering applications are either based on the assumption of infinitely fast chemistry or the flamelet assumption with simple chemistry. The level-set flamelet library approach (FLA) has shown great potential in predicting major species and heat release, as well as intermediate and minor species, where more simple models often fail
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I argue along the following lines: For Wollstonecraft, liberty is independence in two different spheres, one presupposing the other. On the one hand, liberty is independence in relation to others, in the sense of not being vulnerable to their whim or arbitrary will. Call this social, or political, liberty. For liberty understood in this way, infringements do not require individual instances of int
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Authorship, anonymity and the liberty of the press in Denmark in the eighteenth century: By using the national bibliography of Denmark it is possible to get an impression of change in matters of anonymity and authorship from the eighteenth to the nineteenth century. Furthermore, a case study of the poet, 'nouvelliste' and pamphleteer Jacob Christian Bie sheds light on conditions for writing and pu
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The explosive popularization of personal computers during the last decade, along with the appearance of the World Wide Web and of high-level programming techniques, has opened many new and exciting opportunities in the field of education. In this chapter, a review of existing types of multimedia material used in education and of some of the authoring tools used in the production of this material i
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This chapter is devoted to modeling and optimization techniques applicable to communication network design and planning. The main emphasis is put on the models dealing with optimization of the capacity of network resources and traffic routing that lead to tractable optimization problems. It is a common belief that the right means for such modeling are multicommodity flow networks (MFN). MFN form a