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Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl

Multidimensional microstructure imaging

In diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflecIn diffusion MRI (dMRI), images are sensitised to water diffusion by the application of magnetic field gradients. Cell membranes hinder the diffusional motion and thereby contribute to the contrast in dMRI. Thus, the diffusion of water molecules is used a probe of tissue microstructure. Data from dMRI is often analysed using diffusion tensor imaging (DTI), which yields image biomarkers that reflec

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Based on the principle of Freedom of Association, sports traditionally hold a unique role in society with a significant level of autonomy. This autonomy has allowed Sports Governing Bodies to establish their own rules and regulatory frameworks with limited external interference and has led to the perception that the governance of sports operate outside the general legal society. Over time however,

Pre-GMP Facility

Pre-GMP faciliteten är ett dedikerat supportcenter för ATMP-utvecklare vid Lunds universitet. Vi förser både interna och externa forskare och utvecklare med den expertis, infrastruktur och utrustning som krävs för att överbrygga klyftan mellan tidig forskning och GMP-tillverkning. Vårt uppdrag är att påskynda omsättningen av ATMP-innovationer till kliniska behandlingar, och att samtidigt minimerThe Pre-GMP Facility is a dedicated support center for ATMP developers at Lund University. We provide both internal and external researchers and developers with the expertise, infrastructure, and equipment necessary to bridge the gap between early-stage discovery and GMP manufacturing. Our mission is to accelerate the translation of ATMP innovations into clinical-grade therapies, reducing time, c

Studentstöd och lärande

Avdelningen Studentstöd och lärande ger service och stöd till studenter och består av tre arbetsgrupper: Pedagogiskt studentstöd, Studieverkstaden och SI-verksamhet.

Studentportalen

Studentportalen är en webbplats som är tillgänglig för alla studenter och innehåller studentnära service i form av IT-tjänster för studenterna vid Lunds universitet. IT-tjänsterna ligger bakom inloggning och endast studenter med ett studentkonto kommer åt IT-tjänsterna.

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OBJECTIVE: To deepen the knowledge of frail elderly patients' preferences for participation in medical decision making during hospitalization.METHODS: Qualitative study using content analysis of semi-structured interviews.RESULTS: Patient participation to frail elderly means information, not the wish to take part in decisions about their medical treatments. They view the hospital care system as an

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In order to determine the mode of beat-to-beat decay of contractility from very high levels, we studied the beat-by-beat decay of cardiac contractility following potentiation. Such decay curves are normally analysed using a mono-exponential decay function, which assumes that a fixed fraction of activator calcium ions is recirculated from one beat to the next. We postulated that there might be devi

MECW: The Middle East in the Contemporary World

The Middle East in the Contemporary World (MECW) is a multi- and transdisciplinary strategic research area, hosted and supported by the Center for Middle Eastern Studies, comprising staff from five different faculties at Lund University.

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We present an approach for connecting and coordinating distributed devices with different capabilities. More specifically, our research focuses on the design of an domain specific language that allows end-users to coordinate devices in pervasive systems.

Kemisk biologi med inriktning mot läkemedelsutveckling

Injectable Bioresorbable Organic Bioelectronics Neuropharmacology—our ambition is to supplement classical biochemical signaling with the modulation of bioelectricity using both ionic and electronic processes. We focus on organic electronics that self-assemble directly inside or near the nervous system to form electronic circuits that mimic its structure and organization, enabling seamless integratInjectable Bioresorbable Organic Bioelectronics Neuropharmacology—our ambition is to supplement classical biochemical signaling with the modulation of bioelectricity using both ionic and electronic processes. We focus on organic electronics that self-assemble directly inside or near the nervous system to form electronic circuits that mimic its structure and organization, enabling seamless integrat

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IntroductionRecreational hunting in Sweden can be depicted as being embedded in two different but overlapping cultural and socio-economic contexts. One is the traditional non-commercial and stewardship-oriented form hunting, in Swedish called ‘allmoge’ hunting. It is characterised by a democratic hunting tradition where the local hunting team is ascribed a main role in wildlife management. These tThe paper is based on a study of hunting tourism enterprising in Sweden. The study examines how hunting tourism businesses in Sweden navigate in a complex social, economic and moral environment. The aim of the present paper is to identify how tensions between a market- oriented value sphere and a value sphere based on friendship- and community reciprocity are played out in hunting tourism entrepre

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This bachelor’s thesis in Historical Archaeology concerns how the royal medals of the Swedish King Gustav III (1756-1792) functioned as a means of political propaganda, namely in what ways an official legitimizing narrative was created about the country’s economy and the role of the King herein, through the images and texts of the royal medals. Inspired by Clifford Geertz’ anthropological perspec

Lund University Bioimaging Center

Our mission is to establish a major trans-faculty bio-imaging center at Lund University (Lund University Bioimaging Center), combining knowledge in the fields of medical physics, preclinical and clinical medicine, chemistry, technology and applied mathematics in order to develop imaging methods for the advanced study of human morphology, cellular metabolism and physiological function in health and