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Drug company funding can create conflicts of interest that compromise the integrity of patient organizations, a problem studied primarily in Western Europe and North America. To address this research gap, we conducted a case study in Poland, a Central European country. Between 2012 and 2020, 33 companies reported payments worth €13 729 644 to 273 patient organizations in Poland. The funding was hi
Adult neurogenesis continues throughout life but declines dramatically with age and in neurodegenerative disorders such as Alzheimer's disease. In parallel, microglia become activated resulting in chronic inflammation in the aged brain. A unique type of microglia, suggested to support neurogenesis, exists in the subventricular zone (SVZ), but little is known how they are affected by aging. We anal
Background: It is thought that patients with inborn errors of immunity (IEI) are more susceptible to severe coronavirus disease 2019 (COVID-19) than the general population, but a quantification of this potential risk is largely missing. Objective: We assessed the impact of COVID-19 on patients with IEI. Methods: A nationwide cohort study was performed to estimate the relative risk (RR) for hospita
BACKGROUND: Physical activity (PA) after stroke has significant health benefits if it is conducted regularly, with sufficient intensity and duration. Because of the health benefits, it is important to identify those below the World Health Organization (WHO) recommended level of PA. However, few studies have assessed the level of PA after stroke in relation to the WHO recommendations and which soci
Aims: Reirradiation is becoming more frequently used in paediatric tumours of the central nervous system (CNS). To fill the void of clinical guidelines, the Swedish Working Group of Paediatric Radiotherapy compiled consensus guidelines on reirradiation in 2019. The aim of this study was to evaluate the outcome of children reirradiated for CNS tumours since implementing the guidelines. Material and
OBJECTIVE - To evaluate proinsulin secretion in different types of NIDDM. RESEARCH DESIGN AND METHODS - Proinsulin and insulin were evaluated at diagnosis of diabetes and 3 years later (fasting and after stimulation with intravenous glucose and glucagon) in 10 NIDDM patients without islet cell antibodies (ICAs) at diagnosis (age 52 ± 4 years), 11 NIDDM patients with ICAs at diagnosis (age 50 ± 5 y
The social network was evaluated by means of the self-rating scale 'Interview Schedule for Social Interaction' (ISSI) and semi-structured interviews in married patients with a DSM-III diagnosis of schizoaffective disorder (N = 17, partners, N = 16), married patients with diabetes (N = 10, partners, N = 10) and in married healthy individuals (N = 8, partners, N = 8). The two latter groups were comp
This study is an attempt to improve the loading and release potential of silver oxide nanoparticles (AgO NPs) using Oleic acid based bio-surfactant isolated from Enteromorpha instestinalis. The isolated Oleic acid based bio-surfactant was characterized using GC–MS, NMR, and HPLC. The AgO NPs were then surface-functionalized with the bio-surfactant and analyzed using XRD, HR-TEM/SAED, DLS, UV–Vis,
Background: The coronavirus disease 2019 (COVID-19) pandemic calls for effective and safe treatments. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 actively replicates in the throat, unlike SARS-CoV, and shows high pharyngeal viral shedding even in patients with mild symptoms of the disease. HCoV-229E is one of four coronaviruses causing the common cold. In this stu
Crowdfunding in tourism and leisure projects appears to be growing. However, little is known about why individuals participate in incentive crowdfunding from a theoretical perspective. To address the research question, this study aims to compare a theoretically integrated model regarding linkages among antecedents, attribution, trust, and behavior. This study conducted an online survey to collect
Background: Patients on home hemodialysis (HHD) exhibit superior survival compared with patients on institutional hemodialysis (IHD) and peritoneal dialysis (PD). There is a sparsity of reports comparing morbidity between HHD and IHD or PD and none in a European population. The aim of this study is to compare morbidity between modalities in a Swedish population. Methods: The Swedish Renal Registry
This report opens a new window on Quaternary tectonics of the Outer Western Carpathians. We discuss results of fractured clasts analysis in Quaternary fluvial gravels within a 4.500 km2 large area comprising a part of the Outer Carpathians including Nowy Sącz Intramontane Basin (NSIB) as well as in the innermost part of the Carpathian Foredeep. Quaternary gravels bearing fractured clasts are wides
1. Geographically widespread species provide excellent opportunities to investigate how phenotypes change across large-scale environmental gradients. Temperature is a fundamental environmental variable and an important determinant of insect fitness. However, field research is often geographically restricted, and typically concentrated in northern latitudes. Basic population biology and phenotypic
Background: We aimed to study the effect of social containment mandates on ACS presentation during COVID-19 pandemic using location activity and mobility data from mobile phone map services. Methods: We conducted a cross-sectional study using data from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) including all ACS presentations during the pandemic until 7 May 2020. Using a cou
Man brukar höra att evolution handlar om att de starkaste, de bäst lämpade, överlever. Detta för tankarna till en värld full med översittare, som hänsynslöst driver fram och lämnar de svaga bakom sig. Men det behöver inte vara så. Denna avhandling visar oss att gemenskap är styrka, och att evolutionen skapar liv där de svaga ibland sitter på de starkas axlar.Strutsar är märkliga varelser. De ser uPeople are used to hearing that evolution is about the survival of the fittest. Theyimagine a world full of bullies that ruthlessly fight their way to the top in the struggle for life, leaving the weak behind. But this doesn’t need be the case. This thesis reveals a different side of evolution, where survival means working together, and where the weak can ride on the shoulders of the fit.Ostriches
