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CONTEXT: Early prediction of dysglycemia is crucial to prevent progression to type 2 diabetes. The 1-hour postload plasma glucose (PG) is reported to be a better predictor of dysglycemia than fasting plasma glucose (FPG), 2-hour PG, or glycated hemoglobin (HbA1c). OBJECTIVE: To evaluate the predictive performance of clinical markers, metabolites, HbA1c, and PG and serum insulin (INS) levels during
Avhandlingen omfattar fyra delarbeten av olika slag, där två är rent laborativa studier av odlade Leishmaniaparasiter och deras interaktion med humant immunsvar, och två berör epidemiologi och diagnostik av sjukdomen leishmaniasis i ett svenskt patientmaterial.This doctoral thesis consists of four separate papers, in which we; investigate epidemiological and clinical aspects of leishmaniasis in Sweden in order to increase awareness of the disease, elucidate some aspects of the interaction of the parasite and the human immune system and validate serological tools as a complement for diagnosis of leishmaniasis.
Popular Abstract in Swedish Målet för ceramologisk forskning är att studera och beskriva keramikhantverkstraditioner : krukmakarna, deras produktion och sociala organisation samt användningen af keramikprodukterna. Kunskapen om keramiken gör det möjligt också att studera de mänskliga handlingarna, som keramiken tog del i. Den föreliggande avhandlingen söker att avtäcka kontakt-mönstre mellan olikaThe objective of ceramology is to describe pottery craft traditions; the potters, their production, social organisation and the use of the products. Through this the human actions surrounding the pottery are studied. The objective of the research presented in this thesis is to study patterns of contacts between different, contemporary sites within a limited area through a ceramological analysis of
Current paper presents the results of investigating of multifunctional Ti-Si-N coatings. Ti-Si-N coatings have been deposited using CAVD method with the aim of studying their chemical, physical, structural and mechanical properties. Coatings of Ti-Si-N were modified by high-intensity ion implantation using copper ions with dose D = 2 × 1017 ions/cm2 and energy E = 60 keV. The results demonstrated
Focusing on the Swedish census of 1900, the child-woman ratio and own-children method have been applied to assess socioeconomic differences in fertility. These indirect estimates of fertility have been compared to the vital statistics at the national level to assess their reliability. This comparison demonstrated that the estimated results suffered from few errors. Even if these indirect estimates
OBJECTIVE: In patients with chronic radicular pain, we aimed to evaluate subgroup differences in 1-yr response to transforaminal epidural steroid injection. DESIGN: In this longitudinal cohort study of 100 subjects, 170 transforaminal epidural steroid injections were performed for 1 yr. The sample was stratified by type of disc herniation (protrusion n = 57, extrusion n = 27), by location of disc
During development, hematopoietic cells originate from endothelium in a process known as endothelial-to-hematopoietic transition (EHT). To study human EHT, we coupled flow cytometry and single-cell transcriptional analyses of human pluripotent stem cell-derived CD34(+) cells. The resulting transcriptional hierarchy showed a continuum of endothelial and hematopoietic signatures. At the interface of
The field flatness and the layout of the stabilization system in a drift tube linac are strongly dependent on the manufacturing errors that affect the local resonant frequency. In this paper a methodology is presented to study, firstly, the sensitivityof the resonant frequency and of the field flatness to each geometrical parameter of the drift tubes; then a set of tolerances for each parameter i
This work concerns an experimental study of pressure drop and heat transfer for turbulent flow inside a U-duct. Such duct geometries can be found in many engineering applications where cooling air extracts heat from hot internal walls of the duct, e.g., passage cooling inside gas turbine blades. Both friction factors and convective heat transfer coefficients were measured inside a U-duct for three
Wireless communication systems are by nature and by regulations limited in bandwidth and hence capacity. Services with high demands on quality of service (QoS) will enforce high demands on the available capacity. This observation motivates the development of schedulers that can deliver the required QoS as well as being resource efficient. In this paper, we provide expressions of the worst case del
Dynamic chromatin structure is a fundamental property of gene transcriptional regulation, and has emerged as a critical modulator of physiological processes during cellular differentiation and development. Analysis of chromatin structure using molecular biology and biochemical assays in rare somatic stem and progenitor cells is key for understanding these processes but poses a great challenge beca
Psychiatric and metabolic features appear several years before motor disturbances in the neurodegenerative Huntington's disease (HD), caused by an expanded CAG repeat in the huntingtin (HTT) gene. Although the mechanisms leading to these aspects are unknown, dysfunction in the hypothalamus, a brain region controlling emotion and metabolism, has been suggested. A direct link between the expression
Pathogenic microbes acquire the human plasma protein plasminogen to their surface. In this article, we characterize binding of this important coagulation regulator to the respiratory pathogen nontypeable Haemophilus influenzae and identify the Haemophilus surface protein E (PE) as a new plasminogen-binding protein. Plasminogen binds dose dependently to intact bacteria and to purified PE. The plasm
Structural and electronic properties of TiO2 nanoparticles sensitized with a set of RuII(tpy)(2) based dyes have been investigated using density functional theory (DFT) calculations combined with time-dependent (TD) DFT calculations. The effects of carboxylic and phosphonic acid anchor groups, as well as a phenylene spacer group, on the optical properties of the dyes and the electronic interaction
Context. The Si III] 1892 angstrom intercombination line shows an anomalously high intensity in spectra of the radiation-rich Weigelt blobs in the vicinity of Eta Carinae. The line disappears during the 100 days long spectral events occurring every 5.5 years. Aims. The aim is to investigate whether resonance-enhanced two-photon ionization (RETPI) is a plausible excitation mechanism for the Si III]
Time-resolved absorption spectroscopy was used to study the femtosecond and picosecond time scale electron injection from the excited singlet and triplet states of Ru(dcbpY)(2)(NCS)(2) (RuN3) into titanium dioxide (TiO2) nanocrystalline particle film in acetonitrile. The fastest resolved time constant of similar to30 fs was shown to reflect a sum of two parallel ultrafast processes, nonergodic ele
