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Acute infection with the intestinal parasite Trichuris muris has long-term consequences on mucosal mast cell homeostasis and epithelial integrity

A hallmark of parasite infection is the accumulation of innate immune cells, notably granulocytes and mast cells, at the site of infection. While this is typically viewed as a transient response, with the tissue returning to steady state once the infection is cleared, we found that mast cells accumulated in the large-intestinal epithelium following infection with the nematode Trichuris muris and p

A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts

Despite intense research, PE_PGRS proteins still represent an intriguing aspect of mycobacterial pathogenesis. These cell surface proteins influence virulence in several pathogenic species, but their diverse and exact functions remain unclear. Herein, we focussed on a PE_PGRS member from Mycobacterium marinum, MMAR_0242, characterized by an extended and unique C-terminal domain. We demonstrate tha

The Unseen War: Rethinking IHL’s Applicability to Mexico’s Armed Conflict with Drug Cartels

This thesis argues that the escalating and protracted violence in Mexico, commonly known as the ‘war on drugs,’ constitutes a non-international armed conflict (NIAC) under international humanitarian law (IHL), calling for a formal application of this legal framework. Despite its devastating humanitarian consequences, the conflict is often mischaracterised within a law enforcement paradigm, contrib

Strain-Distinct α-Synuclein and Tau Cross-Seeding Uncovered by Correlative Approach with Optical Photothermal Infrared Sub-Micron Imaging

The co-occurrence of α-synuclein (αSyn) and Tau in synucleinopathies and tauopathies suggests a complex interplay between these proteins. Their cross-seeding enhances fibrillization, leading to the formation of diverse amyloid-specific structures enriched with β-sheets, which may influence their biological functions. However, existing tools cannot differentiate structural polymorphs directly in ce

Pathogenesis and novel treatment against tuberculosis

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains one of the deadliest infectious diseases worldwide. In 2023, it accounted for approximately 1.25 million deaths, including 161,000 among individuals living with HIV, making it the leading cause of death from a single infectious agent. The growing prevalence of multidrug-resistant TB (MDR-TB) further complicates treatment and contribu

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Arbetstagarnyckeln 2 Arbetstagarorganisation Saco-S centralt Saco, Sveriges akademikers centralorganisation, består av 21 självständiga förbund som tillsam mans har drygt 970 000 medlemmar. Det förbund som är medlem i Saco kan även vara medlem i Saco-S. Saco-S är förhandlingsorganisationen för Sacoförbundens statligt anställda medlemmar. Saco-S högsta beslutande organ är representantskapet, där al

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/saco-s/presentationer/arbetstagarnyckeln_25.pdf - 2026-05-30

Check list for employees

Check list for employees 2022-10-13 Checklist for New Employees and Visiting Scholars Room: ___________________________ Telephone: ___________________________ Email: ___________________________ Departmental mailing lists: personal@fil.lu.se (only personnel and visiting scholars) personal@lucs.lu.se (cognitive science group) The newsletter of the Faculty of Humanities and Theology “HT-bulletin” and

https://www.fil.lu.se/fileadmin/user_upload/fil/dokument/pdf/Check_list_for_employees_221013.pdf - 2026-06-06

Nyheter i Proplan

Nyheter i Proplan | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan int

https://www.lth.se/lthin/utbildningsadministration/kursutbud/nyheter-i-proplan/ - 2026-06-06

In the Absence of Law. The legal frame of an Non-Profit Association's General Assembly resolution.

The first aim of this study is to investigate what it takes for a nonprofit association (NPA) to become a legal entity, specifically regarding requirements addressing decision-making organs within the NPA’s organization. Secondly, since within the legal framework of associations there exist general principles of law, this study also explores which general principles of law are applicable to a gene

Conscientious Objection and Access to Lawful Abortion in the Council of Europe System - Does Conscientious Objection Undermine Legal Abortion Rights?

Historiskt sett har människor gjort invändningar grundade på tankefrihet, samvetsfrihet och religionsfrihet i förhållande till obligatorisk värnpliktstjänstgöring. Denna samvetsvägran inom militären är en erkänd rätt i nationella, regionala och internationella människorättsinstrument. I den Europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna är denna rätHistorically, objections based on the freedom of thought, conscience and religion have been invoked in relation to compulsory military service. These conscientious objections are protected by national, regional and international human rights instruments. In the European Convention on Human Rights this right is grounded in Article 9 on the freedom of thought, conscience and religion. In Europe, the

Investment-Based Optimisation of Green Hydrogen Production for Mobility Use

This thesis investigates the financial viability of green hydrogen production for mobility applications across four European countries: Germany, Norway, Denmark and Spain. Given the rising importance of hydrogen in hard-to-electrify sectors such as (heavy-duty) transport, the study focuses on understanding how system design and local energy conditions influence the Levelised Cost of Hydrogen (LCOH

En egen hörna på biblioteket : en studie av ungdomsavdelningar på tre stadsbibliotek

In the ongoing library debate part of the focus has been on youth in libraries and how many libraries find them to be a challenging group to work with due to some occurring disturbances. In some cases the youth sections start to lean towards being youth recreation centers. Youth need somewhere to be that isn’t home or school and since there aren’t many open, free of cost public spaces, and many ci

Determining the Extent of Procedural Safeguards in Expulsion Proceedings – A Study of the Scope and Compatibility of the Guarantees Set Out in Article 1 of Protocol No. 7 ECHR

Det är statens suveräna rätt att reglera utlänningars närvaro inom dess territorium. Denna rätt är däremot inte utan begränsningar. Artikel 1 i protokoll nr. 7 till Europeiska konventionen om skydd för de mänskliga rättigheterna säkerställer rättssäkerhetsgarantier i samband med utvisningen av utlänningar. Dessa rättssäkerhetsgarantier måste tillgodoses vid utvisningsförfarandet i de medlemsstaterIt is the sovereign prerogative of the state to regulate the presence of aliens within its territory. This right, however, is not without limits. Article 1 of Protocol No. 7 to the European Convention on Human Rights ensures procedural safeguards relating to the expulsion of aliens. These safeguards must be considered in expulsion proceedings by those Member States having ratified the protocol.

Pollen-stratigraphic position of the last Baltic Ice Lake drainage

Populärvetenskaplig sammanfattning: Klimatväxlingarna under sista istiden har alltid varit en debattfråga. Denna istids kallaste period inträffade för cirka 20.000 år sedan och benämns "istidsmaximum". Då var havsytan hundratjugo meter lägre än idag och det mesta vattnet var bundet i inlandsisarna. Klimatväxlingar försöker dagens kvartärgeologer att fastställa med en så bra tidsutlösningHigh-resolution analyses of sediments from two sites in Blekinge, south-eastern Sweden (the former Lake Togölen and Lake Bredsjön), were evaluated in order to establish the pollenstratigraphical position of the second and final drainage of the Baltic Ice Lake in relation to the Younger Dryas-Preboreal pollen zone transition. Remanent magnetisation and magnetic susceptibility were used to correlate

Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions.

The complement system is activated in the vasculature during thrombotic and inflammatory conditions. Activation may be associated with chronic inflammation on the endothelial surface leading to complement deposition. Complement mutations allow uninhibited complement activation to occur on platelets, neutrophils, monocytes, and aggregates thereof, as well as on red blood cells and endothelial cells