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Arrhythmogenic right ventricular cardiomyopathy (ARVC) and cardiac sarcoidosis (CS) can show significant overlap in their clinical presentation. Differentiation between both is crucial for optimal patient management. Aim of this study is to develop an ECG-based machine learning model to distinguish between ARCV and CS patients. The study population included 100 patients (50 with ARCV and 50 with C

Vad återstår i dag av de platser som arbetar rörelsenskapade åt sig själv, och som utnämndes till platserför folket? Vilka spår kan vi se av dessa i landskapet?Vilka berättelser om och minnen från sådana platserlever ännu kvar?

BACKGROUND: Toll-like receptors enable the host to recognize a large number of pathogen-associated molecular patterns such as bacterial lipopolysaccharide, viral RNA, CpG-containing DNA and flagellin. Toll-like receptors have also been shown to play a pivotal role in both innate and adaptive immune responses. The role of Toll-like receptors as a primary part of our microbe defense system has been

High-throughput omics data often contain systematic biases introduced during various steps of sample processing and data generation. As the source of these biases is usually unknown, it is difficult to select an optimal normalization method for a given data set. To facilitate this process, we introduce the open-source tool "Normalyzer". It normalizes the data with 12 different normalization method

In the recently completed and formally ratified new series and stage classification of the Ordovician System, the base of the Middle Ordovician Series coincides with the base of the global Dapingian Stage. In the Global Stratotype Section and Point (GSSP) of this stage, which is located at Huanghuachang in southern China, the base of the Dapingian Stage is defined its the level of first appearance

Complex traits, including inflammatory rheumatic diseases, have important genetic features, but most of the responsible genes have not been conclusively identified. Genetic analysis of inbred animal models and comparative genetics - the comparison of genes between different species - might help to identify the crucial genes and to investigate more directly the biology involved. Genome-wide linkage

The essay focuses on the apophatic tradition, Western metaphysics, and the unknown God. It presents Jaspers' thoughts on transcendence as an eye-opener. To take the issue of the unknown God, two philosophers are highlighted, David Hume and Simone Weil. For Hume the concept of the unknown God presents the problem of how might anything that is unknown have any moral influence on human beings? Simone

By using absorption and fluorescence (steady-state and time-resolved) techniques the interaction between a poly(acrylic acid) PAA, randomly grafted with pyrene (Py) units (PAAMePy55) and a triblock copolymer of poly(ethylene oxide) and poly(propylene oxide) (EO20PO68EO20, P123) was investigated. From the fluorescence data it is shown that upon addition of P123 a decrease of the (pyrene-pyrene, Py-

The dynamic phase diagram of triethylene glycol dodecyl ether (C12E3) in D2O was determined for 40, 50, and 60 wt % of surfactant. The shear flow effect on the nonionic lamellar phase was investigated as a function of temperature and concentration. The transition from planar lamellae (L-alpha)-to-multilamellar vesicles (MLVs) was characterized by means of rheology, rheo-small-angle neutron and lig

Extracellular High Mobility Group Box 1 (HMGB1) has been associated with acute and chronic inflammatory conditions. However, little is known about HMGB1 in necrotizing bacterial infections. We hypothesized that the local HMGB1 response is excessive in severe soft tissue infections (STIs), which are characterized by necrosis and hyperinflammation. To explore this, tissue biopsies were collected fro

The association between a randomly pyrene labeled PAA polymer (PAAMePy55) and a PEO-PPO-PEO triblock copolymer (P123) in aqueous solutions of different NaCl concentrations and pHs has been studied by means of dynamic light scattering (DLS) and steady-state fluorescence spectroscopy at 40 °C. At acidic pH values, in the low P123/PAAMePy55 molar ratio regime (i.e., at low P123 concentrations), the r

Background The Chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) blocks the Complement fragment C5a receptor (C5aR) and formylated peptide receptor (FPR) and is thereby a potent inhibitor of neutrophil chemotaxis and activation of inflammatory responses. The majority of the healthy human population has antibodies against CHIPS that have been shown to interfere with its function in vit

We investigate the properties of multifractal products of the exponential of stationary diffusion processes defined by stochastic differential equations with linear drift and certain form of the diffusion coefficient corresponding to a variety of marginal distribution.

Popular Abstract in Swedish Den här avhandlingen innehåller fyra uppsatser som på ett eller annat sätt relaterar till befolkningsströmningar såsom dess ekonomiska konsekvenser och orsaker. I den första uppsatsen används en hushållsundersökning från Kina för att undersöka huruvida utbildning bidrar till att höja inkomsterna hos hushåll i jordbrukssektorn. Genom regressionsanalys uppmäts korrelatioAbstract Population movements are more substantial today than at any other point in human history. If managed effectively, migration can be beneficial for all aspects of social and economic life. This thesis contains four papers, all of which are related to the economic consequences and determinants of migration, within and across countries. The first paper employs a household survey to explore

Context The relationship of platelet function testing measurements with outcomes in patients with acute coronary syndromes (ACS) initially managed medically without revascularization is unknown. Objective To characterize the differences and evaluate clinical outcomes associated with platelet reactivity among patients with ACS treated with clopidogrel or prasugrel. Design, Setting, and Patients Pat

The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. An important tool in detecting and studying bnAbs, are neutralization assays. Here we d

This thesis is an empirical study of how positioning is achieved in interactional Swedish. Positioning has previously been described in terms of epistemic modality, interpersonal positioning, stanceand speech act adverbials. The aims of the study are, firstly, to identify what linguistic resources are used to achieve positioning in interaction. A second aim is to describe where in the turn-con

Karyotype structures of Scenedesmus acuminatus (Lagerch.) Chod. and Scenedesmus pectinatus Meyen are compared. The karyotype of S. acuminatus (n = 5) is described for the first time. It reveals four large metacentric and one large submeta centric chromosomes (4M + 1SM). The established karyotype differences have been helpful in clarifying the taxonomic position of these two species. The cytologica