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Parkinson´s disease (PD) is one of the most common neurological diseases with both motor and non-motor symptoms that can be perceived as difficult to control despite medical treatment. This leads to several consequences in everyday life for example difficulties in activities of daily living (ADL), sometimes already at diagnosis. Therefore, rehabilitation is important to manage the consequences of

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Aim: This study investigated the changes in health-related quality of life from diagnosis to 1 year after diagnosis in breast cancer (BC) patients and the influence of clinical, psychological, and sociodemographic variables. An additional aim was to explore the mediating and moderating effects of resilience on changes in health-related quality of life. Methods: A longitudinal population-based stud

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Purpose: To assess the ability of MRI-DTI to evaluate growth plate morphology and activity compared with that of histomorphometry and micro-CT in rabbits. Methods: The hind limbs of female rabbits aged 16, 20, and 24 wk (n = 4 per age group) were studied using a 9.4T MRI scanner with a multi-gradient echo 3D sequence and DTI in 14 directions (b-value = 984 s/mm2). After MRI, the right and left hin

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Thick GaN layers with a low concentration of defects are the key to enable next-generation vertical power electronic devices. Here, we explore hot-wall metalorganic chemical vapor deposition (MOCVD) for the development of GaN homoepitaxy. We propose a new approach to grow high-quality homoepitaxial GaN in N2-rich carrier gas and at a higher supersaturation as compared to heteroepitaxy. We develop

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Purpose: The relationship between prostate-specific antigen (PSA) level and prostate cancer risk remains subject to fundamental disagreements. We hypothesized that the risk of prostate cancer on biopsy for a given PSA level is affected by identifiable characteristics of the cohort under study. Experimental Design: We used data from five European and three U.S. cohorts of men undergoing biopsy for

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We have developed a direct immunofluorescence technique utilising chelates of the lanthanide ions europium and terbium conjugated to monoclonal IgGs (Mabs) against prostate-specific antigen (PSA) and alpha-1- antichymotrypsin (ACT) for the detection and quantification on the same tissue section. Strong signals without disturbance from tissue autofluorescence were demonstrated in paraffin sections

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Purpose Pretreatment prostate-specific antigen (PSA) dynamics (PSA velocity and PSA doubling time) are widely advocated as useful prognostic markers in prostate cancer. We aimed to assess the published evidence for the clinical utility of PSA dynamics in this population. Methods We conducted a systematic review of studies published before March 2007 in which a PSA dynamic (velocity or doubling tim

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The European Academy of Andrology (EAA) celebrates its 30th anniversary in 2022. An important part of the Academy's history is its scientific publishing activity, which started with the International Journal of Andrology (Int J Androl), and continued with Andrology, the journal created and overseen jointly by the EAA and the American Society of Andrology (ASA). The year 2022 marks the first decade

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Appropriate evaluation and experimental design are fundamental for empirical sciences, particularly in data-driven fields. Due to the successes in computational modeling of languages, for instance, research outcomes are having an increasingly immediate impact on end users. As the gap in adoption by end users decreases, the need increases to ensure that tools and models developed by the research co

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Makerspaces are shared workshops for the public to design, innovate and prototype. These spaces are primarily located in the urban regions and provide access to 'high-tech' and traditional low-tech tools needed for innovation design. Though makerspaces are a western phenomenon, their emergence in India can be traced to the early decade of the 2010s. In this paper, we study the urban makerspaces in

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Background: Gallstones intervention during pregnancy might be a stressful event for both mother and fetus and stress might affect outcome. The aim of this study was to identify factors that might improve the care of pregnant patients in need of intervention for gallstone disease. Methods: By crossmatching the Swedish Registry of Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography

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Groundwater contamination caused by the use of the aqueous film-forming foam (AFFF) containing per- and polyfluoroalkyl substances (PFAS) was investigated in southern Sweden. ΣPFAS concentrations in groundwater ranged between 20 and 20,000 ng L−1; PFAS composition was primarily represented by PFOS and PFHxS. The PFAS chain length was suggested to have an impact on the contaminant distribution and

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COVID-19 is a systemic disease, frequently affecting kidney function. Dexamethasone is standard treatment in severe COVID-19 cases, and is considered to increase plasma levels of cystatin C. However, this has not been studied in COVID-19. Glomerular filtration rate (GFR) is a clinically important indicator of renal function, but often estimated using equations (eGFR) based on filtered metabolites.

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OBJECTIVE: Access to effective treatments for adolescents with depression needs to improve. Few studies have evaluated behavioural activation (BA) for adolescent depression, and none remotely delivered BA. This study explored the feasibility and acceptability of therapist-guided and self-guided internet-delivered BA (I-BA) in preparation for a future randomised controlled trial (RCT). DESIGN: A si

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Purpose - The purpose of this paper is to acquire strict upper and lower bounds on quantities of slender beams on Winkler foundation in finite element analysis. Design/methodology/approach - It leans on the dual analysis wherein the constitutive relation error (CRE) is used to perform goal-oriented error estimation. Due to the coupling of the displacement field and the stress field in the equilibr

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Background and Purpose: Hippocampal-sparing (HS) is a method that can potentially reduce late cognitive complications for pediatric medulloblastoma (MB) patients treated with craniospinal proton therapy (PT). The aim of this study was to investigate robustness and dosimetric plan verification of pencil beam scanning HS PT. Materials and Methods: HS and non-HS PT plans for the whole brain part of c

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An outbreak of acidity and sulphate salts was observed on the hull of the 17th-century Swedish warship Vasa, following humidity variations in the Vasa Museum during the rainy summer in 2000. Analyses of total sulphur in oak cores sampled from 16 locations showed, in the outermost 2 cm., mean concentrations betwen 0.2 and 6 mass percent. Synchrotron-based sulphur K-edge X-ray absorption spectroscop

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After the early biomineralisation event in the early Paleozoic (Cambrian –Ordovician; 541 – 443.8 Ma), the Late Triassic (237 – 201.3 Ma) represents another key period of biomineralisation with the onset of the Mesozoic plankton radiation. In the Carnian (237 – 227 Ma), the first calcifying dinoflagellates are recorded followed by the nannoliths in the middle Norian (Alaunian) and the coccolithoph