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Prevalence of zinc transporter 8 antibodies in gestational diabetes mellitus.

Aims: Gestational diabetes mellitus affects approximately 7% of all pregnant women. Some of these women develop autoantibodies that are generally characteristic of Type 1 diabetes. Autoantibodies targeting glutamic acid decarboxylase and tyrosine phosphatase-like protein are the most frequently reported. A recently identified autoantigen in Type 1 diabetes is zinc transporter 8. Some reports sugg

Interaction with C4b-binding protein contributes to nontypeable Haemophilus influenzae serum resistance.

Complement evasion by various mechanisms is important for microbial virulence and survival in the host. One strategy used by some pathogenic bacteria is to bind the complement inhibitor of the classical pathway, C4b-binding protein (C4BP). In this study, we have identified a novel interaction between nontypeable Haemophilus influenzae (NTHi) and C4BP, whereas the majority of the typeable H. influe

Immunome knowledge base (IKB): an integrated service for immunome research.

Functioning of the immune system requires the coordinated expression and action of many genes and proteins. With the emergence of high-throughput technologies, a great amount of molecular data is available for the genes and proteins of the immune system. However, these data are scattered into several databases and literature and therefore integration is needed.

High isolation compact four-port MIMO antenna systems with built-in filters as isolation structure

In this work, we present a built-in filter method to enhance the isolation level between closely packed MIMO antennas. The built-in filter is composed of several slits etched on the ground of the antenna structure. The number and length of slits depend on both the resonance frequency and the structure of the MIMO antenna system. To illustrate its usefulness, two designs of compact planar four-port

Expressing ‘confirmation’ in Swedish: the interplay of word and utterance prosody

An exploratory study on the prosodic signaling of ‘confirmation’ in Swedish is presented. Pairs of subjects read short dialogs, constructed around selected target words, in a conversational style. A falling utterance intonation was found on the target word, and the signaling of word prosody (lexical pitch accent) appeared to be, to a certain degree, optional.

Infertility, ethics, and the future: an exploration

This chapter explores current and prospective reproductive technologies and some of their likely implications for reproductive and family ethics and policymaking. The technologies discussed include uterus transplants, mitochondrial transfer, ectogenesis, the development of in vitro gametes, and solo reproduction. The chapter considers the impact of these developments on the content of concepts suc

Nationalism

What is nationalism? When did it originate and how did it develop throughout the centuries? What types of nationalism have evolved in different sociopolitical settings and why? By addressing these questions, this entry seeks to address the key issues of the conceptualization of nationalism, followed by an analysis of its development in different structural, cultural, and political contexts. The en

Postanoxic electrographic status epilepticus and serum biomarkers of brain injury

Aim: To explore if electrographic status epilepticus (ESE) after cardiac arrest causes additional secondary brain injury reflected by serum levels of two novel biomarkers of brain injury: neurofilament light chain (NfL) originating from neurons and glial fibrillary acidic protein (GFAP) from glial cells. Methods: Simplified continuous EEG (cEEG) and serum levels of NfL and GFAP, sampled at 24, 48

Variation of satellite estimated LAI due to the impact of the ground vegetation cover

The contribution of the understorey vegetation to the spectral reflectance from the top of a forest canopy was investigated by the use of a forest canopy reflectance model. Detailed field data, i.e. forest leaf area index (LAI), tree structural parameters like the height, diameter and crown length of the trees, and the composition, distribution and reflectance of the forest floor, was collected fo

Key aspects of membrane plant operations related to fouling and cleaning in the food industry

Fouling is one the most important challenges to apply membrane technology on industrial scale in the food industry. Despite significant progress in understanding and preventing fouling and in developing appropriate membrane cleaning protocols, both fouling and cleaning remain key challenges in membrane plant operation in the food industry with a significant impact on membrane plants capital (CAPEX

Comparison of Bayesian techniques for the before–after evaluation of the safety effectiveness of short 2+1 road sections

In evaluating the effectiveness of a road safety treatment, the regression to the mean phenomenon is a cause for concern because of a possible overestimation of benefits. Therefore, Bayesian approaches are usually suggested as the most appropriate methodologies for before—after studies as they account for regression to the mean effects. The empirical Bayes (EB) methodology examines the estimation

Endothelial cells expressing an inflammatory phenotype are lysed by superantigen-targeted cytotoxic T cells

The objective of this study was to investigate whether the superantigen staphylococcal enterotoxin A (SEA), which binds to HLA class II and T-cell receptor Vβ chains, can direct cytotoxic T cells to lyse cytokine-stimulated endothelial cells (EC). In addition, we wanted to determine whether SEA- primed cytotoxic T cells could be targeted to EC surface molecules as a means of a novel cancer immunot

Exploring sensory perception, appraisal and concern: An approach to support design activity

The fundamental first stage of product interaction is through sensory perception, which generates cognitive and affective experiences. Product perception through sensory feedback is a major component in the end user product appraisal that precedes the elicitation of product emotion. Sensory evaluation is connected to a set of concepts including appraisal, concern and goal oriented objective. The i

Recommended guidelines for reviewing, reporting, and conducting research on post-resuscitation care : The Utstein style

The aim of this report is to establish recommendations for reviewing, reporting, and conducting research during the post-resuscitation period in hospital. It defines data that are needed for research and more specialised registries and therefore supplements the recently updated Utstein template for resuscitation registries. The updated Utstein template and the out-of-hospital "Chain of Survival" d