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The purpose of this article is to analyse quality attributes of regional public transport and their influence on modal choice, demand, and customer satisfaction through a literature review. The review is based on a working definition of regional public transport with boundaries toward local as well as interregional public transport: Regional public transport (i) targets passengers travelling betwe
We reconstructed a record of the micrometeorite flux in the Late Cretaceous using the distribution of extraterrestrial spinel grains across an ~2 m.y. interval of elevated 3He in the Turonian Stage (ca. 92–90 Ma). From ~30 m of the limestone succession in the Bottaccione section, Italy, a total of 979 kg of rock from levels below and within the 3He excursion yielded 603 spinel grains (32–355 µm si
BACKGROUND: Patients on dialysis who have an acute myocardial infarction (AMI) have an exceedingly poor prognosis, but it is unknown to what extent guideline-recommended interventions and treatments are used and to which benefit. We aimed to assess temporal changes in the use of treatments and survival rates in dialysis patients with an AMI. METHODS AND RESULTS: All consecutive AMI cases from 1996
Indoor combustion processes associated with cooking, heating, and smoking are a major source of aerosols in Jordanian dwellings. To evaluate human exposure to combustion-generated aerosols in Jordanian indoor environments, regional inhaled deposited dose rates of indoor aerosols (10 nm to 25 µm) were determined for different scenarios for adult occupants. The inhaled deposited dose rate provides a
Aim: To estimate the occurrence of complications related to early-onset type 2 diabetes compared with type 1 diabetes. Methods: All individuals registered in the Swedish Pediatric Quality Diabetes Register and the Swedish National Diabetes Register with type 2 diabetes diagnosis at 10 to 25 years of age between 1996 and 2014 (n = 1413) were included. As controls, individuals with type 1 diabetes w
The establishment of introduced species in new environments is today widely acknowledged as a potential threat to biodiversity, and many plants that are known to be invasive have obviously spread from gardens. Thus, in the context of biosecurity, we need to consider how contemporary gardeners think about which plants and animals are welcome in their gardens. In this chapter we look at vegetation i
Central nervous system (CNS) involvement is rare in patients with Hodgkin lymphoma (HL). Thus, the clinical features and outcomes are not well described. Cases of histologically confirmed CNS HL diagnosed between 1995 and 2015 were retrospectively identified in institutional (n = 7), national (n = 2), and cooperative group (n = 1) databases. We screened 30,781 patients with HL in our combined data
BACKGROUND: Although the association between cytosine-adenine-guanine (CAG) repeat length and age at onset of Huntington's disease is well known, improved prediction of onset would be advantageous for clinical trial design and prognostic counselling. We compared various measures for tracking progression and predicting conversion to manifest Huntington's disease.METHODS: In this prospective observa
Impulsivity is common in Parkinson's disease even in the absence of impulse control disorders. It is likely to be multifactorial, including a dopaminergic 'overdose' and structural changes in the frontostriatal circuits for motor control. In addition, we proposed that changes in serotonergic projections to the forebrain also contribute to response inhibition in Parkinson's disease, based on precli
Clinical outcome after traumatic diffuse axonal injury (DAI) is difficult to predict. In this study, three magnetic resonance imaging (MRI) sequences were used to quantify the anatomical distribution of lesions, to grade DAI according to the Adams grading system, and to evaluate the value of lesion localization in combination with clinical prognostic factors to improve outcome prediction. Thirty p
Some evidences suggest that obesity impairs the effectiveness of TNF inhibitors. We examined the impact of body mass index (BMI) on the clinical effectiveness of abatacept in rheumatoid arthritis (RA) patients. This is a pooled analysis of 10 prospective cohorts of RA patients. All patients with available BMI were included in this study. The primary endpoint was drug retention of abatacept in the
Popular Abstract in Swedish Bakgrund Varje nervskada, oavsett orsak, utgör ett stort problem för den drabbade individen och slutresultatet är i regel dåligt. Personerna som drabbas av nervskador är ofta i arbetsför ålder. Rehabilitering efter en nervskada medför vanligtvis lång sjukskrivning och ibland måste patienten skolas om till ett nytt yrke. Detta innebär stora kostnader för både individen
Popular Abstract in Swedish Nanotekniken håller i skrivande stund på att revolutionera samhället med nya innovationer inom exempelvis elektronik och medicin. En viktig del i detta är utvecklingen av nya och förbättrade sätt att avbilda strukturer av nanometerstorlek (en nanometer är en miljarddels meter). Avancerade karakteriseringsmetoder skapar en ökad förståelse för hur nanostrukturer beter sigUltrafast nano-optics is a new and quickly evolving research field centred around the control, manipulation, and application of light on a nanometre and femtosecond scale. This can lead to improved electro-optical devices, more sensitive spectroscopy, and real-time control of chemical reactions. However, understanding the simultaneous nanometre and femtosecond evolution of nano-optical fields requ
We studied the prevalence of musculoskeletal pain and its impact on performance in orchestra musicians and in a reference group of actors, who share the mental stress in a performance situation, but without having the physical work load from an instrument. Swedish musicians (n = 103) from symphony and chamber orchestras and actors (n = 106) participated in a cross-sectional questionnaire study. Mu
In a prospective study of a consecutive breast cancer series accumulated in the period 1978-82, the S-phase fraction (SPF) and ploidy status were determined by flow cytometry performed on cell nuclei derived from samples of 580 primary tumors. Sixty percent of the tumors were non-diploid. After correction for debris the median SPF values were 7.3% overall, 12% for non-diploid tumors, and 2.9% for
The effects of hypothermia on hypoglycemic brain damage were studied in rats after a 30-min period of hypoglycemic coma, defined as cessation of spontaneous EEG activity. The rats were either normothermic (37 degrees C) or moderately hypothermic (33 degrees C). Morphological brain damage was evaluated after various periods of recovery. Hypothermic animals with halothane anesthesia never resumed sp
A novel method has been developed for acquiring the correct alignment of a query sequence against remotely homologous proteins by extracting structural information from profiles of multiple structure alignment. A systematic search algorithm combined with a group of score functions based on sequence information and structural information has been introduced in this procedure. A limited number of to
Chinese hamster ovary (CHO) cells in the plateau phase were seeded in the absence or presence of 5 mM 2-difluoromethylornithine (F(2)MeOrn), an enzyme-activated irreversible inhibitor of ornithine decarboxylase. The thymidine analogue bromodeoxyuridine (BrdUrd, 5 mu M) was added to the culture medium 30 min before sampling of the cells, which occurred 1-17 h after seeding. Using flow cytometry, co
Accurate measurements of soil solution electrical conductivity (or.) are needed in various applications. One recently developed technique that measures sigma(w) is the Sigma Probe (SP). The SP is supposed to give accurate readings only-slightly dependent on water content (theta) and soil type. To test the performance of the SP, it was compared with another dielectric technique, time domain reflect
