Sökresultat

The human ribosomal protein S19 gene (RPS19) is mutated in approximately 20% of patients with Diamond-Black fan anemia (DBA), a congenital disease with a specific defect in erythropoiesis. The clinical expression of DBA is highly variable, and subclinical phenotypes may be revealed by elevated erythrocyte deaminase (eADA) activity only. In mice, complete loss of Rps19 results in early embryonic le

Dactylorhiza traunsteineri is an allotetraploid species that belongs to the large Dactylorhiza incarnata/maculata polyploid complex of the Eurasian genus Dactylorhiza (Orchidaceae). Here, eight polymorphic microsatellite loci were isolated using selective hybridization according to the FIASCO protocol (fast isolation by AFLP of sequences containing repeats) with slight modifications. The number of

In today’s business landscape the view and role of the customer, or market, in shaping and guiding strategy and the competitive advantage of a business, is given increasing attention within many areas of business theory. By definition the supply chain discipline focuses on suppliers from the perspective of the manufacturer, not customers. However this paper illustrates the use of the supply chain

In this article we give an overview of some challenges in how to make geospatial information more useable and accessible. We also suggest a roadmap for dealing with these challenges – and introduce a new EU project HaptiMap.

Projects often suffer from lack of logistics considerations in the early phases. Since logistics is not the main focus of the people involved in the project, logistics solutions become reactive rather than proactive. With the increasing global competition, forcing companies to shorten time-to-market for their projects and becoming more cost effective, it becomes increasingly important to manage pr

The partitioning of 10% (w/w) lactic acid in ethylene oxide propylene oxide (EOPO) random copolymers and dextran T500 aqueous two-phase systems was studied. An analysis of variance design was applied to investigate the effect of pH, polymer concentration, and addition of polyethyleneimine to the aqueous two-phase systems. The lowest lactate partition coefficient of 0.09 was obtained at pH 6 in the

Agriculture in many African countries is characterised by large diversity in production and great variation in growing conditions, irrigation potential and access to markets. This variation has proved to be a difficult matter when adjusting national agricultural policies and development projects to local conditions. In the face of the recent trend of less support for agricultural extension servic

We report on large scale ab initio calculation for the 4s(2) S-1(0)-4s4p P-1,3(0,1,2) transitions in the zinc-like sequence, using the multiconfiguration Dirac Fock ( MCDF) method. Our attention is focused on the spin-forbidden transition 4s(2) S-1(0)-4s4p P-3(1) and the hyperfine- induced ( HPF) transition 4s(2) S-1(0)-4s4p P-3(0) for ions between Z = 30 ( Zn) and Z = 47 ( Ag). Our results provid

Wastewater treatment plant operators encounter complex operational problems related to the activated sludge process and usually respond to these by applying their own intuition and by taking advantage of what they have learnt from past experiences of similar problems. However, previous process experiences are not easy to integrate in numerical control, and new tools must be developed to enable re-

Galectins are implicated in a large variety of biological functions, many of which depend on their carbohydrate-binding ability. Fifteen members of the family have been identified in vertebrates based on binding to galactose (Gal) that is mediated by one or two, evolutionarily conserved, carbohydrate-recognition domains (CRDs). Variations in glycan structures expressed on glycoconjugates at the ce

In Australia a national public/private telematics framework has been established, which is administered by Transport Certification Australia (TCA). The first application was the Intelligent Access Program (IAP), which has enabled several road transport reforms by managing infrastructure risks associated with the operation of extra heavy vehicle configurations. The paper uses the IAP to demonstrate