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Arsenic exposure and early biomarkers of cardiovascular disease and cancer

AbstractInorganic arsenic exposure through drinking water is a serious public health concern because of its association to cancer and non-cancer diseases. More than one hundred million people world-wide are exposed to elevated levels of arsenic on a regular basis. Arsenic is classified as class I carcinogen by International Agency for Research on Cancer (IARC). Recent report shows that arsenic exp

Kinematic analysis of the Large Magellanic Cloud using Gaia DR3

Context. The high quality of the Gaia mission data has allowed for studies of the internal kinematics of the Large Magellanic Cloud (LMC) to be undertaken in unprecedented detail, providing insights into the non-axisymmetric structure of its disc. Recent works by the Gaia Collaboration have already made use of the excellent proper motions of Gaia DR2 and Gaia EDR3 for a first analysis of this sort

Toward Creating a Coherent, Next-Generation Light Source with special emphasis on nonlinear harmonic generation in single-pass, high-gain free-electron lasers

Popular Abstract in Swedish De mest briljanta ljuskällor som finns idag är de så kallade synkrotronljuskällorna som kan generera ljus över ett mycket brett våglängdsspectrum, från synligt ljus ända till mycket korta våglängder - röntgenstrålar. Det existerar många sådana faciliteter runt om i världen och de används dagligen i olika experiment för att öka våra kunskaper om material på en mikrospopiThere is a strong desire for short wavelength (~1 Å), short pulsewidth (<100 fs), high-brightness, transverse and longitudinally coherent light pulses for use by the synchrotron radiation community. These requirements exceed the limits achievable by existing, so-called, "third-generation" light sources, such as the Advanced Photon Source (APS) at Argonne National Laboratory (ANL), USA, the Europea

Born Near the Limit of Viability : Developmental Outcomes 2.5 Years Later

Popular Abstract in Swedish Bakgrund Neonatal intensivvård är under ständig utveckling, vilket medfört att allt mindre barn överlever efter att ha fötts prematurt. Ett tydligt mått på detta är att gränsen för livsduglighet (den gestationsålder då individen beräknas ha 50% chans att överleva) har skjutits bakåt till att under de senaste två decennierna ligga runt graviditetsvecka 24. Barn som föds Although advances in neonatal care have resulted in increased survival rates among extremely preterm infants (born < 28 gestational weeks), they still face substantial morbidity risks during the neonatal period. The question of possible later outcomes is a key issue faced by health care professionals working with these infants. Objectives The objective of the present thesis was to explore develo

Positioning for lumbar puncture in newborn infants

BACKGROUND: Lumbar puncture is a common invasive procedure performed in newborns for diagnostic and therapeutic purposes. Approximately one in two lumbar punctures fail, resulting in both short- and long-term negative consequences for the clinical management of patients. The most common positions used to perform lumbar puncture are the lateral decubitus and sitting position, and each can impact th

Unraveling UVB effects : Catalase activity and molecular alterations in the stratum corneum

Aim: Ultraviolet B (UVB) radiation can compromise the functionality of the skin barrier through various mechanisms. We hypothesize that UVB induce photochemical alterations in the components of the outermost layer of the skin, known as the stratum corneum (SC), and modulate its antioxidative defense mechanisms. Catalase is a well-known antioxidative enzyme found in the SC where it acts to scavenge

Pregnancy and leisure time physical activity

ABSTRACT Aims: To examine associations between leisure time physical activity before and during pregnancy and preterm delivery, birth weight, and pre-eclampsia and to describe levels of physical activity prior to and during pregnancy. Furthermore to elucidate women’s experiences and views of leisure time physical activity during pregnancy in a qualitative study. Methods: Data sources were: the Aar

Gradient-Based Distributed Model Predictive Control

The thesis covers different topics related to model predictive control (MPC) and particularly distributed model predictive control (DMPC). One topic of the thesis is gradient-based optimization algorithms for solving the optimization problem arising in DMPC in a distributed manner. The underlying idea is to solve the optimization problem in distributed fashion using dual decomposition, which is a

Fermi Observations of GRB 090510: A Short-Hard Gamma-Ray Burst With an Additional, Hard Power-Law Component From 10 Kev To Gev Energies

We present detailed observations of the bright short-hard gamma-ray burst GRB 090510 made with the Gammaray Burst Monitor (GBM) and Large Area Telescope (LAT) on board the Fermi observatory. GRB 090510 is the first burst detected by the LAT that shows strong evidence for a deviation from a Band spectral fitting function during the prompt emission phase. The time-integrated spectrum is fit by the s

A Chemometric Approach to Process Monitoring and Control - With Applications to Wastewater Treatment Operation

Popular Abstract in Swedish För att styra, övervaka och utvärdera processer inom processindustrin, samlas stora mängder data från mätgivare i olika delar av processen. Den tekniska utvecklingen inom mätteknik- och datorområdet har gjort det möjligt att mäta många olika storheter. Inom processindustrin kan antalet vara mycket stort; hundratals och ibland tusentals värden loggas kontinuerligt med inIn this work, various aspects of multivariate monitoring and control of wastewater treatment operation are discussed. A number of important difficulties face operators and process engineers when handling online measurements from wastewater treatment processes. These include, for instance, a high number of correlated measurement variables, non-stationarities, nonlinearities and multiscale process b

The effects of temperature on avian physiology, behavior and development

Popular Abstract in Swedish Omgivningens temperatur är kanske en av de faktorer som i allra störst utsträckning påverkar djur och deras livsmiljö. Detta bottnar givetvis till stor del i temperaturens effekt på naturen. Betänk till exempel årstidsväxlingarna; att vintern blir till vår, och att hösten (i samband med de första snöfallen) allt mer skrider mot ännu en kall och vit vinter bestäms och reTemperature is a property of profound matter in all aspects of animal life, affecting both individual energy budgets and the environments in which animals reside. Thus, a proper understanding of the effects of temperature variation is instrumental in understanding not only animal form and function, but also the structure and dynamics of wild populations. Accordingly, the aims of this thesis were t

A comparison of customer perceived service quality in discount versus traditional grocery stores.

Purpose -- The overall purpose of this study is to enhance the understanding of customer perceived service quality within grocery retailing in a North European context. We do this by comparing customer perceived service quality evaluations of the traditional supermarket store with evaluations of the discount store. Design/methodology/approach -- This study is based on empirical data from four stor

Motorik, koncentrationsförmåga och skolprestationer : en interventionsstudie i skolår 1-3

Popular Abstract in Swedish Denna studie visar betydelsen av ökad idrottsundervisning, fysisk aktivitet och extra motorisk träning i skolan. Undersökningen är en delstudie i Bunkefloprojektet - en hälsofrämjande livsstil. Interventionen består i att två årskullar elever har en obligatorisk rörelselektion varje skoldag. Motorikobservationer med MUGI observationsschema som underlag genomförs varje åThe aim of this thesis is to study effects of an extension of physical education/activity and motor training on motor skills, attention and cognition during a period of three years. Another aim is to develop a test, MUGI observationsschema, which could be useful in charting motor skills of school pupils. The study has two intervention groups (n=152) that have physical activity and motor training o

Vi och dom och alla dom andra andra på Komvux : Etnicitet, genus och klass i samspel

Popular Abstract in Swedish Syftet med den här avhandlingen har varit att förstå hur grupper av vi och dom skapas och består, framför allt inom utbildning och skola, och särskilt inom gymnasiala Komvux. I vardagligt tal menar människor oftast att dom är invandrare, medan vi är svenskar. Jag har visat att denna uppdelning, som sker nästan automatiskt, är alltför förenklad och svart-vit. Ett undersyThis thesis, set in an educational context (Swedish Komvux, high school adult education), deals with how groups of us and them are constructed, changed and reproduced. In order to understand the processes of us and them I have looked at the interconnections between gender, ethnicity and class utilising participant observations and semi-structured interviews. The main theoretical points of departu

Konversion och konfession – om konversionsliknande övergångar hos Henric Schartau och F. G. Hedberg i relation till en andra konfessionaliseringsperiod

Conversion and Confession – Religious Transitions similar to Conversion in Henric Schartau and F. G. Hedberg, related to a Second Confessional Age The nineteenth century has often been called an Age of Secularisation. This has been criticized as blindness of religion. The »long» nineteenth century meant a mobilization of religion. German Historian Olaf Blaschke has interpreted the period as a sec

Studies in Human Capital, Ability and Migration

Popular Abstract in Swedish Avhandlingen innehåller ett inledningskapitel följt av fyra separata studier. Studierna behandlar olika aspekter av humankapital, begåvning och immigration. I den första studien, Ability and Rates of Return to Schooling ? making use of the Swedish Enlistment Battery Test, används det svenska mönstringstestet för att skatta avkastningen på utbildningen för individer medThis thesis consists of an introductory chapter followed by four separate papers. The papers deal with various aspects of human capital, ability and migration. Using the Swedish Military Enlistment test, the first paper, Ability and Rates of Return to Schooling ? making use of the Swedish Enlistment Battery Test, estimates the return to schooling for individuals belonging to different parts of th

Neural Progenitor Cells in malignancy and injury of the brain. A Trojan Horse fro gliomas?

Popular Abstract in Swedish Gliom är en familj av hjärntumörer som är graderade beroende på hur snabbt och på vilket sätt de växer. Grad IV även kallad glioblastoma multiforme, är den mest elakartade av dessa. Patienter har en medelöverlevnadsprognos på ca 12 månader med behandling, såsom kirurgi, kemo- och strålningsterapi. Tumörerna är heterogena, vilket innebär att celler har flera typer av mutGliomas are neoplasms arising in the central nervous system (CNS), and constitute the most common primary brain tumor. They are classified depending on the grade and morphology, from grade I, pilocytic astrocytoma, to grade IV, glioblastoma multiforme (GBM). Glioblastomas constitute a great challenge in treatment due to their disseminating nature. Classical treatments such as surgery, radiation th

Detailed Soot Modelling in Laminar and Turbulent Reacting Flows.

In the present work a detailed kinetic soot model is applied to study the formation and oxidation of soot particles in laminar premixed and turbulent non-premixed flames. The soot model used in this study is based on a detailed description of the chemical and physical processes involved in the formation of soot. In the first part of the study the soot model is extended to include the formation of

Kyrkan som sakrament. Henri de Lubacs fundamentalecklesiologi.

Popular Abstract in Swedish Avhandlingen diskuterar den sakramentala kyrkosynen hos den franske, romersk-katolske, teologen Henri de Lubac (1896-1991). Utgångpunkt är hans formulering (i ?Catholicisme? 1938): ?Om Kristus är Guds Sakrament, så är Kyrkan för oss Kristi sakrament. Hon (kyrkan) re-presenterar honom (Kristus), med detta ords hela urgamla kraft: hon gör honom i sanning närvarande.? ForThe thesis provides a discussion of the ecclesiology of the French Roman-Catholic theologian Henri de Lubac SJ (1896-1991) by showing how this is determined by his method of fundamental theology. I establish the term ?fundamental ecclesiology? for this inter-dependance of form and content, subject and object in theology; this is why his ecclesiology is sacramental in structure. I primarily use tex

Test and evaluation plans

interactIVe introduces safety systems that autonomously brake and steer. The driver is continuously supported by interactIVe assistance systems. They warn the driver in potentially dangerous situations. The systems do not only react to driving situations, but are also able to actively intervene in order to protect occupants and vulnerable road users. The objective of interactIVe is to develop new