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This thesis aims at describing the developmental patterns of text production in four text types: spoken and written narrative texts, and spoken and written expository texts (n=316), produced by four age groups: 10-year-olds, 13-year-olds, 17-year-olds and university students (n=79). It explores material from an experimental study with a cross-sectional design comprising spoken texts recorded on vi
Bacillus subtilis can grow on glycerol or glycerol-3-phosphate (G3P) as the sole carbon and energy source. The glpD gene encodes G3P dehydrogenase which is required for the catabolism of glycerol and G3P. In the non-coding leader sequence of glpD there is an inverted repeat followed by a run of AT basepairs which has been shown to function as a Rho-independent terminator (a stem-loop structure fol
Prostatacancer är den vanligaste cancern bland män i Sverige. Varje år insjuknar ca 10 000. Sjukdomen är starkt åldersberoende och är mycket vanlig bland äldre män. Latent cancer (icke kliniskt signifikant) förekommer ofta. Sjukdomen klassificeras som låg, mellan eller högrisk baserat på Gleason summa (tumörens aggressivitet), stadium och PSA. Val av behandling sker utifrån riskgrupp och ålder. LåAbstract Backgound Prostate cancer is the most common form of cancer in men in Sweden. Radiotherapy, including external beam radiation therapy (EBRT) and brachytherapy (BT), is important treatment alternatives to surgery and active surveillance. Precise delivery of the prescribed absorbed dose to the prostate with minimal irradiation of normal tissue, specifically organs at risk, is crucial for op
BACKGROUND: Patellofemoral arthroplasty (PFA) is one option for the treatment of isolated patellofemoral osteoarthritis, but there are limited data regarding the procedure and results. Because isolated patellofemoral arthritis is relatively uncommon, available case series generally are small, and even within national registries, sample sizes are limited. Combining data from multiple registries may
Case endings are an important marker of fuṣḥā but are by most native speakers considered complicated and difficult. They typically appear only sporadically even in the most formal speech styles. There has been relatively little academic interest in the use of case endings in speech. Research has been characterized by largely impressionistic accounts (Badawi 1973, Meiseles 1977) and more recently b
Popular Abstract in Swedish Vi lever i en tid då klimatförändringar är en fråga som engagerar, men det krävs en djupare förståelse för hur och varför vårt klimat har förändrats för att möjliggöra realistiska förutsägelser om framtiden. Efterhand som olika metoder för att rekonstruera klimatförändringar har förfinats, och nya dateringsmetoder har utvecklats, så har förståelsen för hur klimatet föräDendrochronological analysis was applied to subfossil remains of Scots pine (Pinus sylvestris L.) buried in South Swedish peat deposits. By cross-dating Swedish bog-pine ring-width (RW) chronologies with corresponding material from North-west Germany, three Swedish RW chronologies were assigned absolute ages and yielded continuous, dated chronologies over the periods 5284-3728 BC and 2668-1108 BC.
The overall aim of this work was to study knee function movement pattern and knee osteoarthritis in males 14-16 years after anterior cruciate ligament (ACL) injury. In the first study, 154 male subjects with a 14-year-old ACL injury were investigated. Self-reported knee function and radiographic signs of osteoarthritis were assessed. Most of the subjects (122/154) underwent knee radiographs, 78% o
Popular Abstract in Swedish Internationella diabetesförbundet räknar med att en tiondel av världens befolkning kommer att ha någon form av diabetes om 50 år. Diabetes är en sjukdom med global spridning som innebär att kroppen inte kan ta hand om all den näring man intar, framförallt inte sockret. Detta medför att sockerhalten i blodet höjs. Insulin produceras efter en måltid och signalerar till krIslet hormone secretion is tightly regulated by metabolic status as well as local and circulating factors. These factors can activate different receptors on the pancreatic islet cells, for instance G-protein coupled receptors (GPCRs). When activated, these receptors are able to fine-tune islet hormone secretion and regulate overall β-cell function. Estrogen and serotonin are circulating factors t
This thesis focuses on cognitive impairment in Out-of-Hospital Cardiac Arrest (OHCA) survivors with the main aim to evaluate possible effects by targeted temperature management. Secondary aims are to describe the prevalence of cognitive impairment in a large group of OHCA-survivors, the related symptoms of psychological distress and the actual effect of cognitive impairment for the patient’s abili
Background To investigate potential cardiovascular and other effects of long-term pharmacological interleukin 1 (IL-1) inhibition, we studied genetic variants that produce inhibition of IL-1, a master regulator of inflammation. Methods We created a genetic score combining the effects of alleles of two common variants (rs6743376 and rs1542176) that are located upstream of IL1RN, the gene encoding t
Popular Abstract in SwedishDenna arkeologiska studie syftar till att förstå de neolitiska samhällenas framväxt, organisation och förändring kring de västskånska ådalgångarna vid Saxån-Välabäcken och Lödde å-Kävlingeån. Arkeologiska undersökningar och fornminnesinventeringen har visat att området hyser omfattande lämningar av neolitiska bebyggelsekomplex — i form av bosättningar, gravfält, megalitgThis dissertation deals with Early and Middle Neolithic societies in a valley landscape in western Scania, in the southern part of Sweden. Several archaeological excavations conducted by the National Heritage Board have revealed a great number of Neolithic remains in this region. The sites constitute a substantial continuous sequence from the earliest to the latest phase of the Funnel Beaker Cultu
Background: Adult hip dysplasia is one of the few potentially modifiable risk factors for hip osteoarthritis (OA). However, the prevalence of hip dysplasia and the strength of its association with OA are not fullyunderstood.Aims and methods:I. To determine the prevalence of hip dysplasia in a Swedish population and investigate whether the condition was mentioned in radiology reports. The center ed
Radiolabeled targeting agents have emerged as valuable tools for the treatment of disseminated cancer. Monoclonal antibodies (mAbs) are widely employed as carriers for diagnostic and therapeutic radionuclides due to their exceptional specificity and affinity. However, their prolonged circulatory half-life can diminish diagnostic efficacy and increase radiation exposure to non-target tissues in the
Background and Objectives Postanoxic electrographic status epilepticus (PSE) affects up to a third of all comatose patients after cardiac arrest (CA) and is associated with high mortality. Late PSE onset (>24 hours), from a restored continuous background pattern, and absence of established indicators of poor outcome at multimodal prognostication are described in survivors. We aimed to determine th
Context. Galaxies are expected to accrete pristine gas from their surroundings to sustain their star formation over cosmic timescales. This mechanism is well established in models and simulations, but evidence from observations is mostly indirect. These gas inflows leave distinct traces in the chemical composition of newborn stars and alter the distribution of stellar abundances compared to what w
Principen om självbestämmande har färdats långt från sitt ursprung som ett verktyg för politisk retorik till sin nuvarande ställning som en folkrättslig princip gällande erga omnes. Såväl innehållet som tillämpligheten av självbestämmanderätten förblir dock oklar. Detta gäller särskilt nationella minoriteter, som traditionellt inte har tillerkänts denna rättighet. Denna avhandling undersöker därföThe principle of self-determination has come a long way from its origins as a tool for political rhetoric to its current status as a right of international law valid erga omnes. However, the contents of the right to self-determination, as well as its applicability, remain unclear. This holds true especially concerning national minorities, which have not traditionally been considered recipients of
Lignin is the second most abundant biopolymer on Earth after cellulose, found in virtually all plantswhere it is responsible for rigidity, hydrophobicity and mineral transport. For a long time, it has been considereda waste in the paper production process and incinerated for its energy content. However, with the depletion ofcrude oil reserves, it has been found to have a large potential to become
BACKGROUND: In peritoneal dialysis, approximately 40% of the total osmotic ultrafiltration (UF) induced by glucose can be predicted to be due to "free" water transport across aquaporin-1 (APQ-1). Theoretically, it would be possible to assess the fraction of free water transport in the early phase of a hypertonic dwell, when UF rate is high and the relative contribution of Na+ diffusion is low. La
This paper discusses five major parameters in desalination, namely technology, raw-water, energy sources, cost and environmental effects. Both size and yield have grown rapidly in desalination plants due to high performance in technology developments in the last few years. Five different types of desalination technology are presented and bench-marked for long-term use: multistage flash evaporation
Popular Abstract in Swedish På senare år har insikten ökat om hur nödvändigt det är att förstå flyktingars, invandrares och deras barns inre värld (speciellt gäller detta krisdrabbade flyktingar). Dessa grupper har kommit i växande skaror till Skandinavien och många för övrigt säkra och duktiga yrkesmänniskor inom alla områden av den psykiska hälsovården, socialtjänsten och andra fack har känt sigIn recent years, awareness has grown of the necessity of understanding the inner world of refugees (in particular traumatized refugees), immigrants, and their children. These groups have come in increasing numbers to Scandinavia, and otherwise confident and capable professionals in all arenas of mental health, social work and other fields have often felt inadequate when working with them. After m
