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The object of this study was to investigate whether exposure of pipe-layers to thermal degradation products of diphenylmethane diisocyanate (MDI) could be assessed by analysing 4,4-methylenedianiline (MDA) in hydrolysed plasma and urine, and whether the genotype for N-acetylation affected these biomarker levels. Blood and urine samples were drawn from 30-pipe-layers who had been welding polyuretha

DESIGN: Cross-sectional study. SETTING: University-based rehabilitation center. PARTICIPANTS: Tai Chi practitioners (n=24; age+/-SD, 68.5+/-6.6 y) and control subjects (n=20; age, 71.3+/-6.7 y) were recruited. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Measures included the following: (1) subjects' intentional weight shifting to 8 different spatial positions within their base of support

"Such in truth is our lot that while we are English to the Irish, we are Irish to the English. For the one island does not detest us more than the other." The sentiment expressed by the Anglo-Norman knight Maurice Fitzgerald in 1171 was one that many Anglo-Irish shared more than 700 years later. This study deals with an area of Anglo-Irish literature neglected by present-day researchers: novels wr

BACKGROUND: To evaluate resource utilization and direct economic costs of care for patients treated with negative-pressure wound therapy (NPWT), using the Vacuum-Assisted Closure (V.A.C.) system, compared to standard moist wound therapy (MWT). METHODS: A total of 162 diabetic patients with post-amputation wounds (up to the trans-metatarsal level) entered a 16-week, randomized clinical trial. Patie

The method of using short laser and X-ray pulses to investigate dynamics in materials (pump-probe) has been used for several decades. This thesis presents work that was carried out using these sources of light to reveal acoustic, thermal and non-thermal dynamics. The dynamics were induced in the samples by depositing energy with a pulsed laser, and probed with X-ray diffraction. The recent increas

Background: Response to modern treatment strategies, which combine cytotoxic compounds with immune stimulatory agents and targeted treatment is highly variable among MCL patients. Thus, providing prognostic and predictive markers for risk adapted therapy is warranted and molecular information that can help in patient stratification is a necessity. In relapsed MCL, biopsies are rarely available and

Introduction: The osmotic conductance to glucose (OCG) is a crucial determinant of ultrafiltration (UF) in peritoneal dialysis (PD) patients and can be used to monitor membrane integrity in patients on long-term PD. It has been proposed that OCG can be assessed based on drained volumes in 2 consecutive 1-hour glucose dwells, usually 1.5% and 4.25% glucose, in a so-called double mini-peritoneal equ

Introduction: Given considerable focus on health outcomes among childhood cancer survivors, we aimed to explore whether survivor bias is apparent during long-term follow-up of childhood cancer survivors. Methods: We identified all 1-year survivors of cancer diagnosed before 20 years of age in Denmark, Finland, Iceland, and Sweden. From the general population, we randomly sampled a comparison cohor

Factor I (FI) is a serine protease with narrow specificity restricted to activated complement components C3b and C4b. Supported by appropriate cofactors such as factor H or C4b-binding protein, FI cleaves peptide bonds in C3b/C4b after arginyl residues. By doing so it inhibits further propagation of the complement cascade thus contributing to protection from misguided or excessive complement attac

Importance: Better understanding is needed of the degree to which individuals tolerate Alzheimer disease (AD)-like pathological tau with respect to brain structure (brain resilience) and cognition (cognitive resilience). Objective: To examine the demographic (age, sex, and educational level), genetic (APOE-ϵ4 status), and neuroimaging (white matter hyperintensities and cortical thickness) factors

Approximately 20% of the population experience long-term pain. Women are generally more affected than men. Currently, pain researchers advocate a biopsychosocial perspective, which emphasises the importance of addressing psychological and social factors as well as biomedical ones in clinical practice. However, previous research shows that this holistic perspective is not always materialized in med

BACKGROUND AND OBJECTIVES: Dementia cases are expected to triple during the next 30 years, highlighting the importance of finding modifiable risk factors for dementia. The aim of this study is to investigate whether adherence to conventional dietary recommendations or to a modified Mediterranean diet are associated with subsequent lower risk of developing all-cause dementia, Alzheimer's disease (A

The Environmental Determinants of Diabetes in the Young (TEDDY) study enrolled 8676 children, 3-4 months of age, born with HLA-susceptibility genotypes for islet autoimmunity (IA) and type 1 diabetes (T1D). Whole-genome sequencing (WGS) was performed in 1119 children in a nested case-control study design. Telomere length was estimated from WGS data using five tools: Computel, Telseq, Telomerecat,

Across the world, so-called warlord democrats (WDs) – former military or political leaders of armed groups who subsequently enter formal electoral politics – strongly influence the dynamics and trajectory of post-civil war politics. However, scholarship on war-to-peace transitions and post-conflict politics have often failed to pay attention to the agency of these important actors. This article re

Well-differentiated liposarcoma (WDLS) displays amplification of genes on chromosome 12 (Chr12) in supernumerary ring or giant marker chromosomes. These structures have been suggested to develop through chromothripsis, followed by circularization and breakage-fusion-bridge (BFB) cycles. To test this hypothesis, we compared WDLSs with Chr12 amplification in rod-shaped chromosomes with WDLSs with ri

Philosophy played an important role in the Soviet political system becauseit provided ideological legitimization for the regime. Therefore, throughout the existence of the Soviet Union, the authorities and general populations showed a great interest in the works of philosophers. The collapse of the Soviet Union and its Marxist-Leninist ideology led to philosophy’s losing its privileged political s

Background: It is widely accepted that chronic inflammatory bowel diseases significantly higher a risk for colorectal cancer development. Among different types of treatments for patients with colon cancer, novel protein-based therapeutic strategies are considered. AIM: To explore the effect of human plasma alpha-1 antitrypsin (AAT) protein in the chemically induced mouse model of colorectal cancer

Supercritical n-decane is applied in the regenerative cooling system of scramjet engines while scramjets are always in various irregular movements. With the desire to explore heat transfer performance of supercritical n-decane under actual flight conditions, numerical simulations and analysis of different states during the accelerated flight process are carried out under three different heat fluxe

Allmän studieplan för forskarutbildning Page 1 of 9 Faculty Board SYLLABUS Reg. no U 2024/66 Date 14 February 2024 General syllabus for third-cycle studies in Computational Chemistry, NAKEMT02 This syllabus was approved by the Faculty Board on 14 February 2024. It replaces NAKEMT01 and applies to doctoral students admitted from 15 February 2024. The syllabus is based on Chapter 6, Sections 1–11, 2

https://www.science.lu.se/sites/science.lu.se/files/2024-05/Computational%20Chemistry%20general%20syllabus%202024.pdf - 2026-06-03

The voting behavior of the Members of the European Parliament (MEP) has been widely studied. However, little is written about the effects of crises. This thesis tries to understand how the Covid-19 pandemic affected the MEPs voting behavior in relation to their European political group (EPG) and in addition their national party. This was done using the two theories: the two principal dilemma