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We assessed hepatocellular carcinoma (HCC) risk associated with smoking and alcohol consumption and their interactions, using both questionnaire data and objective serum biomarkers. Information on smoking and alcohol consumption was collected at baseline from 450,112 participants of the EPIC cohort, among whom 255 developed HCC after a median follow-up of 14 years. In a nested case–control subset
This study reports findings from the first large-scale experiment investigating whether entrepreneurs differ 1 from other people in their willingness to expose themselves to various forms of uncertainty. A stratified random sample of 700 chief executive officers from the Yangzi delta region in China is compared to 200 control group members. Our findings suggest that in economic decisions, entrepre
Coffee and tea contain numerous antimutagenic and antioxidant components and high levels of caffeine that may protect against colorectal cancer (CRC). We investigated the association between coffee and tea consumption and CRC risk and studied potential effect modification by CYP1A2 and NAT2 genotypes, enzymes involved in the metabolization of caffeine. Data from 477,071 participants (70.2% female)
Twenty-one placentae from type I (insulin-dependent) pregnant diabetic patients, treated with continuous subcutaneous insulin infusion (CSII), were studied morphologically. Despite a near-optimal blood glucose control the placental changes were identical to those previously reported in diabetic pregnancy. The most frequently observed lesion was that of relative placental immaturity; this, when ext
Computer simulations were used to study the effect of a single reinforcement fiber added to a mechanical fibre network. The stresses of the surrounding fibers and inter-fiber bonds increased proportionally to the logarithm of the elastic stiffness of the reinforcement fibre. In the case of fiber failure the breaking stress of the model system increased only little and breaking strain decreased lit
We show that in the absence of trilinear terms in the scalar potential of the Georgi-Machacek model, heavy charged scalars do not necessarily decouple from the h→γγ decay amplitude. In such scenarios, measurement of the Higgs to diphoton signal strength can place stringent constraints in the parameter space. Using the projected precisions at the High Luminosity LHC (HL-LHC) and the ILC, we find th
In events of the type e+e- → tt → bW+bW-, particle production could depend in a non-trivial way on the kinematics of the process. Energetic perturbative gluon radiation can be generated (when kinematically allowed) by the original tt system and by the t → bW+ and t → bW- decays, with negligible interference between the production and decay between the t and t decays. Soft perturbative gluon emissi
A reliable assessment of the optical properties of atmospheric black carbon is of crucial importance for an accurate estimation of radiative forcing. In this study we investigated the spatio-temporal variability of the mass absorption cross-section (MAC) of atmospheric black carbon, defined as light absorption coefficient (σap) divided by elemental carbon mass concentration (mEC). σap and mEC have
This work has been made as a thesis for a BSc degree in Fire Protection Engineering at Lund University. The work has been supported and funded by ESS AB, European Spallation Source, in Lund. ESS AB is a publicly held company, owned by Sweden and Denmark as host countries. These host countries, together with at least 17 other European countries, will build and establish a multidisciplinary research
This book analyzes the current trends in the production, dissemination, and use of knowledge which contribute to social inequalities, especially in the Global South. The aim of the text is to explore the possibilities of active involvement by universities in the democratization of knowledge - a process by which people will be able to more easily acquire and utilize knowledge, as well as the result
Background: There is limited knowledge concerning fall-related activity avoidance in people with Parkinson's disease (PD); such knowledge would be of importance for the development of more efficient PD-care and rehabilitation. This study aimed to examine how fall-related activity avoidance relates to a history of self-reported falls/near falls and fear of falling (FOF) as well as to disease severi
This article investigates the excess-weight penalty in income for men and women in the Swedish labor market, using longitudinal data. It compares two identification strategies, OLS and individual fixed effects, and distinguishes between two main sources of excess-weight penalties, lower productivity because of bad health and discrimination. For men, the analysis finds a significant obesity penalty
The globally widespread kind of description of vowels by points in the IPA quadrangle with the cardinal vowels as references is very often not trustworthy in its detailed specification. The reasonable interpretation of a dot registration is namely that the vowel quality is very narrowly pinpointed. However, most phoneticians do not have the capacity to judge vowels in this detailed way. Consequent
This article studies the maximum likelihood estimates of magnitude and scale parameters for a Gaussian process of Ornstein-Uhlenbeck type used to model a deterministic function that does not have to be a realisation of an Ornstein- Uhlenbeck process. Specifically, we derive explicit expressions for the limiting values of the maximum likelihood estimates as the number of observations increases. The
BACKGROUND: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy (1H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as a disease-modifying therapy for multiple sclerosis. The primary endpoint of this research was the change in prefrontal cortex glutathione concentr
