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När något blir annorlunda : skötsamhet och funktionsförmåga i berättelser om poliosjukdom

When something is different: respectability and bodily ability in stories about polio In this thesis I study the relationship between people’s stories about polio and norms concerning respectability and ability. The purpose is to examine sense-making processes surrounding polio disease. This is done by studying how the ”normality” and ”deviation” is produced and negotiated in individual stories a

Effects of Vagus Nerve Stimulation and Ketogenic Diet on Quality of Life and Changes in EEG and Sleep

Popular Abstract in Swedish De flesta barn som insjuknar i epilepsi tillfrisknar eller blir anfallsfria med hjälp av antiepileptisk medicin. Hos drygt en fjärde del av barnen blir epilepsin svårbehandlad och anfallskontroll är svår att uppnå. Dessa barn ska i första hand erbjudas möjlighet till epilepsikirurgisk utredning och behandling. När epilepsikirurgisk behandling inte är möjlig att utföra eWhen anti-epileptic drugs fail, and epilepsy surgery is found unfeasible or ineffective, there remains a group of at least 25% of children with epilepsy in whom seizure control cannot be achieved. Vagus nerve stimulation (VNS) is an adjunctive treatment for medically refractory epilepsy. It is an implantable, multi-programmable pulse generator that delivers current electrical stimulation to the va

Optimization of recombinant in protein production in an E.coli-based process with limited oxygen transfer

E. coli continues to be a popular host organism for production of recombinant proteins. To obtain a high volumetric productivity at the cultivation stage, it is important to achieve a high cell density and a high specific productivity per cell. In many fed-batch processes, the substrate feed rate eventually becomes limited by the oxygen transfer capacity of the bioreactor. While biomass can contin

Stratigraphy and facies of Middle Silurian epicontinental carbonate platform deposits of Gotland, Sweden

Popular Abstract in Swedish Den sedimentära lagerföljd som bygger upp Gotland avlagrades för drygt 400 miljoner år sedan (under silurperioden) i ett varmt tropiskt innanhav strax söder om ekvatorn. Innanhavet sträckte sig som en vid bukt in över dagens södra Skandinavien, Baltikum och vidare mot sydost, till Ukraina. Avhandlingen behandlar primärt hur sedimentationsmönster utvecklades under cirka The Silurian foreland of Scandinavia included a vast epicontinental carbonate platform system of which the island of Gotland (Sweden) is an erosional remnant. This thesis treats the Late Wenlock succession (Cyrtograptus lundgreni, Pristiograptus dubius parvus, Gothograptus nassa, Colonograptus(?) praedeubeli, and the Co(?) deubeli zones), and emphasises the sedimentology and biostratigraphy of the

The lower and middle Cambrian of Sweden: trilobites, biostratigraphy and intercontinental correlation

Popular Abstract in Swedish Kambrium är ett tidsavsnitt av jordens historia som spänner från ca 542 till 488 miljoner år sedan. Under denna tid utvecklades livet, främst djur, i en rasande takt genom något som brukar kallas den kambriska explosionen, en ekologisk förändring utan dess like. Bland de nya livsformer som fick de kambriska haven att koka av liv märks skalbärande djur som små armfotingaThis thesis is based on studies of Cambrian successions in Sweden, with particular focus on the middle Cambrian biostratigraphy and its correlative relationship to the proposed global agnostoid zonation. The investigated material, mainly trilobites, was collected from both outcrops and drill cores from five provinces in Sweden: Skåne (Scania), Öland, Västergötland, Jämtland and Lapland. The Almba

Unraveling the magnetic carriers of igneous cores from the Atlantic, Pacific, and the southern Indian oceans with rock magnetic characterization

Previous rock magnetic investigations of oceanic basement samples have been mainly restricted by single drill holes of dredge collections. In this study, we present new and published data on the rock magnetic properties of igneous rock samples recovered during seven Ocean Drilling Program (ODP) legs in the Atlantic, Pacific, and the southern Indian oceans. The recovered igneous rocks from these le

Intracellular signaling and cellular plasticity in a rat model of L-DOPA-induced dyskinesia

Popular Abstract in Swedish Parkinsons sjukdom beror på att de dopamin-producerande cellerna i hjärnan dör. Detta leder till minskad rörlighet, svårigheter i att påbörja och avsluta en rörelse, balanssvårigheter och darrningar (tremor) hos de drabbade patienterna. Varför dopamincellerna dör är oklart och i nulägat kan man inte bota Parkinsons sjukdom, men man kan lindra symptomen med mediciner. PaParkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. This works very well during the initial treatment period, but unfortunately a majority of the patients develop abnormal involu

Rural Income Diversification, Employment, and Differentiation in Kenya and Implications for Rural Change

To contribute to contemporary rural development debates, the present thesis conducts a contextual analysis of rural development using Kenya as a case study from the colonial era to today. To perform the analysis, two critical trends in rural Africa are focused on: socioeconomic differentiation and rural income diversification, with a particular focus on large-scale farm employment. By pointing to

Multilingual EFL Students’ Intentional Vocabulary Learning : Multimethods Development Research Based on a Word-Focused Task

Intentional vocabulary learning through tasks with an explicit vocabulary focus is essential for L2 learning (e.g., Laufer, 2005; Nation, 2007, 2022; Schmitt & Schmitt, 2020). Yet, research suggests that in EFL classrooms in Sweden, there tends to be a reliance on incidental learning of vocabulary rather than intentional learning (D. Bergström, 2023). Studies(Eriksson, 2023; Warnby, 2023) also

Computational Modeling and Analysis of Electrophysiology and Hemodynamics During Atrial Fibrillation

Atrial fibrillation (AF) is the most common arrhythmia globally and is characterized by uncoordinated atrial activation and ineffective atrial contraction. Atrial fibrillation is associated with an impaired quality of life and an increased risk of stroke, heart failure, and death. Changes in the autonomic nervous system (ANS) control of cardiac function are a known pathophysiological mechanism in

Global surveillance of cancer survival 1995-2009 : analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million

How can the business potential of products with health claims increase? - A case study of PrimaLiv

The purpose of this master thesis is to investigate the influencing factors of the busi-ness potential of products with health claims, using PrimaLiv as an example, and give recommendations on how a dairy producer, which is present in the Swedish market, could improve the sales rates of products with health claims. We have chosen to put a main focus on the consumers, since they determine the busin

Interactions with pain-related systems - Towards new electrical treatments for chronic pain

Background. Persistent intolerable pain is still an unsolved issue with a huge socioeconomic impact. To develop appropriate treatments, it is crucial to understand the complex mechanisms underlying pain and how they change during sustained pain stimuli or during pathological conditions. In particular, it is essential to clarify how the endogenous analgesic centres which are present in the brain, s

Towards Single-Ion Detection and Single-Photon Storage in Rare-Earth-Ion-Doped Crystals

Solid materials doped with rare-earth ions are considered an attractive platform for quantum information applications. One of the main reasons for this is the exceptionally long optical and hyperfine coherence times of the 4fn states, due to the shielding provided by the outer lying 5s and 5p electrons. This enables a large number of quantum operations before the system loses its coherence. Anothe

Early diagnosis, treatment, and Health-Related Quality of Life in women with mild Breast Cancer-Related Lymphedema.

Bakgrund: Tidig diagnos och behandling av bröstcancer-relaterade lymfödem(BCRL) är viktigt för att förhindra försämring och påverkan på livskvalitet. Vidmindre BCRL i arm, kan det ansamlas lymfvätska lokalt i den ytliga vävnaden, utan en volymökning. Tissue Dielectric Constant (TDC), är en metod som mäter lokal vävnadsvätska i hud och subkutan vävnad och hade inte använts tidigare för att diagnostBackground: Early diagnosis and treatment of Breast Cancer-RelatedLymphedema (BCRL) are important to prevent lymphedema progress and impacton Health-Related Quality of Life (HRQOL). The treatment includes self-care andtreatment with compression garment. In mild BCRL, the lymphedema can be local, without an increase in arm volume. Tissue Dielectric Constant (TDC), measuring local tissue water in sk

Clinical protein science in translational medicine targeting malignant melanoma

Melanoma of the skin is the sixth most common type of cancer in Europe and accounts for 3.4% of all diagnosed cancers. More alarming is the degree of recurrence that occurs with approximately 20% of patients lethally relapsing following treatment. Malignant melanoma is a highly aggressive skin cancer and metastases rapidly extend to the regional lymph nodes (stage 3) and to distal organs (stage 4)