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There are three families of mononuclear molybdenum enzymes that catalyze oxygen atom transfer (OAT) reactions, named after a typical example from each family, viz., dimethyl sulfoxide reductase (DMSOR), sulfite oxidase (SO), and xanthine oxidase (XO). These families differ in the construction of their active sites, with two molybdopterin groups in the DMSOR family, two oxy groups in the SO family,

OBJECTIVE: The aim of this study was to evaluate the feasibility and effect of a water-based exercise program on lymphedema status and shoulder range of motion among women with breast cancer-related lymphedema. DESIGN: This was a single-blinded, randomized controlled pilot trial. Twenty-nine eligible breast cancer survivors (median, 10 yrs after surgery) with arm lymphedema (median, 21% interlimb

Type 1 diabetes mellitus (T1DM) is an autoimmune disorder directed against the β cells of the pancreatic islets. The genetic risk of the disease is linked to HLA-DQ risk alleles and unknown environmental triggers. In most countries, only 10-15% of children or young adults newly diagnosed with T1DM have a first-degree relative with the disease. Autoantibodies against insulin, GAD65, IA-2 or the ZnT

Whistle-blowing can serve as a powerful mechanism helping policy-makers and other stakeholders recognize ethical misconduct and other types of wrongdoing in autonomous public agencies. This mechanism is of particular importance in major public sector reforms, such as agency mergers, when it may be difficult to secure continuity in the quality of organizational processes. Yet, we know little of wha

Summary – 200 words In education today, there is a paradigm shift with critical challenges for Universities to enhance innovation in teaching and learning. Knowledge and learning are critical issues for most companies and private and civil service organizations with today’s rapid changes in socio-economy and technology. The needs for competence development vary along a broad scale from short info

The evolution of a system for the management of fatigue-related risks in airline and maintenance operations is at present a contentious issue. The aspirations for the integration of fatigue risk management processes into existing Safety Management System (SMS) guidelines need to be placed in the realities of the present economic and commercial environment – they therefore need to exhibit relevance

There is a growing body of evidence that the parents of trauma-exposed children report posttraumatic stress symptoms whether they are directly exposed to the same trauma as the child or not. The parents’ symptoms also correlate with the child’s self-reported symptoms – although not as strongly as some might expect. There is a widespread assumption that anxious parents model and reward anxious beha

Respiratory proteins such as myoglobin and hemoglobin can, under oxidative conditions, form ferryl heme iron and protein-based free radicals. Ferryl myoglobin can safely be returned to the ferric oxidation state by electron donation from exogenous reductants via a mechanism that involves two distinct pathways. In addition to direct transfer between the electron donor and ferryl heme edge, there is