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Microbial growth often thrives in humid conditions, at high relative humidity. Moulds are complex organisms; many types of mould are able to survive strong variations in humidity and temperature, such as those on building façades. For some building materials a critical relative humidity is determined, which functions as a theoretical threshold; at this (or lower) relative humidity microbial growt

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Cosmogenic radionuclide records (e.g., 10Be and 14C) contain information on past geomagnetic dipole moment and solar activity changes. Disentangling these signals is challenging, but can be achieved by using independent reconstructions of the geomagnetic dipole moment. Consequently, solar activity reconstructions are directly influenced by the dipole moment uncertainties. Alternatively, the known

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The crucial goal of kidney-sparing surgical resection of a malignant tumor is complete removal of the cancerous tissue. The exact border between the cancerous and normal tissues is not always possible to identify by naked eye, therefore, a supplementary intraoperative diagnosis is needed. Unfortunately, intraoperative pathology methods used nowadays are time consuming and of inadequate quality ren

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Purpose: To provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of the condition in the Western world. Methods: Non-systematic focused literature review. Results: Sickle retinopathy results from aggregation of abnormal hemoglobin

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Diffusion tensor imaging provides increased sensitivity to microstructural tissue changes compared to conventional anatomical imaging but also presents limited specificity. To tackle this problem, the DIAMOND model subdivides the voxel content into diffusion compartments and draws from diffusion-weighted data to estimate compartmental non-central matrix-variate Gamma distributions of diffusion ten

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PURPOSE: Currently, radiologic response of brain tumors is assessed according to the Macdonald criteria 10 weeks from the start of therapy. There exists a critical need to identify nonresponding patients early in the course of their therapy for consideration of alternative treatment strategies. Our study assessed the effectiveness of the parametric response map (PRM) imaging biomarker to provide f

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Världen är föränderlig. För att kunna överleva måste allt liv kunna anpassa sig till rådande förhållanden. För cellen, livets minsta enhet, sker detta bland annat genom reglering av produktionstakten av proteiner, vilka är de molekyler som utför de flesta grundläggande funktioner. En speciell klass av proteiner utgörs av så kallade transkriptionsfaktorer. Dessa slår av eller på en gens produktion Living organisms can be viewed as complex biological machines. In order to function, they must regulate their internal mechanism to do the right thing, at the right time, and in the right amount. Part of this regulation is encoded in gene regulatory networks. These are built up of genes which produce special proteins (transcription factors, tf) that regulate other tf-producing genes. Thus a networ

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Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term survival of patients with advanced cancers1. Current predictive biomarkers for therapy response include high levels of intratumour immunological activity, a high tumour mutational burden and specific characteristics of the gut microbiota2,3. Although the role of T c

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The shipping industry is of great importance within the European Union since approximately 90 per cent of the Unions external trade goes by sea. There have been several block exemptions that have enabled, and simplified for liner consortia to cooperate and on the 26th of April 2010 a new exemption will enter into force. This thesis focuses on this new exemption and its aim is to investigate under

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Purpose: The purpose of this thesis is to gain knowledge and visualize significant issues that a future leadership of the Øresund Region should take into consideration in order to promote regional development. Context: In 2000 Copenhagen in Denmark and Malmö in Sweden got connected by the 18km long Øresund Bridge. The bridge’s explicit purpose was not only to physically connect Denmark and Sweden

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Am I allowed to help? – The care manager’s new dilemma Authors: Thea Nilsson Svegard and Helena Rülf Title: Am I allowed to help? – The care manager’s new dilemma Supervisor: Staffan Blomberg Assessor: Alexandru Panican The aim of this essay was to examine how care managers working with elderly look upon their own role in relation to customer-choice. The customer-choice reform is spreading rapi