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A secreted collagen and fibronectin-binding streptococcal protein modulates cell-mediated collagen gel contraction and interstitial fluid pressure

Fibroblast-mediated collagen gel contraction depends on collagen-binding ss1 integrins. Perturbation of these integrins reveals an alternative contraction process that is integrin aVss3-dependent and platelet-derived growth factor (PDGF) BB-stimulated. Connective tissue cells actively control interstitial fluid pressure (IFP) and inflammation-induced lowering of IFP provides a driving force for ed

Comparative visual function in five sciaenid fishes inhabiting Chesapeake Bay

Maintaining optimal visual performance is a difficult task in the photodynamic coastal and estuarine waters in which western North Atlantic sciaenid fishes support substantial commercial and recreational fisheries. Unavoidable tradeoffs exist between visual sensitivity and resolution, yet sciaenid visual systems have not been characterized despite strong species-specific ecomorphological and micro

A smoke-free kitchen: initiating community based co-production for cleaner cooking and cuts in carbon emissions

Cooking over open fire with solid fuels results in incomplete combustion and indoor air pollution (IAP) causing respiratory and other diseases leading to nearly two million premature deaths per year. In urban areas, IAP interacts with outdoor pollutants in toxic chemical mixtures affecting also other citizens and damaging regional air quality in terms of 'brown clouds'. Deaths result mainly in wom

Logistics-driven packaging innovation: a case study at IKEA

Purpose – To identify and describe the strategic potential of logistics-driven packaging innovation in retail supply chains, and suggest propositions for further research and development, providing practitioners with a better basis on which to make strategic packaging and logistics decisions. Design/methodology/approach – An in-depth case study was conducted at a large global retailer which had im

The supply and demand of net primary production in the Sahel

Net primary production (NPP) is the principal source of energy for ecosystems and, by extension, human populations that depend on them. The relationship between the supply and demand of NPP is important for the assessment of socio-ecological vulnerability. We present an analysis of the supply and demand of NPP in the Sahel using NPP estimates from the MODIS sensor and agri-environmental data from

Transcriptional analysis of the pheromone gland of the turnip moth, Agrotis segetum (Noctuidae), reveals candidate genes involved in pheromone production.

Moths generally rely on pheromone communication for mate finding. The pheromone components of most moths are produced by a common pathway of fatty-acid biosynthesis coupled with species-specific modifications of the final products. Some genes involved in moth pheromone production have previously been described, whereas others remain to be characterized and thus the molecular mechanisms accounting

A multi-method approach to dating middle and late Quaternary high relative sea-level events on NW Svalbard - A case study

Waxing and waning ice sheets and changing sea levels have been interpreted from the Quaternary stratigraphic record at Leinstranda, Broggerhalvoya in NW Svalbard. We have identified seven high relative sea-level events, related to glacio-isostatic loading, and separated by at least four glacial events. To establish a chronology for the high sea-level events (interstadials and interglacials) and th

Prophylaxis and treatment of HIV-1 infection in pregnancy: Swedish Recommendations 2010

Prophylaxis and treatment with antiretroviral drugs and the use of elective caesarean section have resulted in a very low mother-to-child transmission of human immunodeficiency virus (HIV) during recent years. The availability of new antiretroviral drugs, updated general treatment guidelines and increasing knowledge of the importance of drug resistance, have necessitated regular revisions of the "

Heraclius Learns Humility: Two Early Latin Accounts Composed for the Celebration of Exaltatio Crucis

The medieval western image of the Byzantine emperor Heraclius (c. 575-641) was largely formed by a Latin legend (BHL 4178) composed for the celebration of Exaltatio Crucis (14 Sept.). The main purpose of the article is to present a critical edition of this legend, together with an editio princeps of a Latin sermon (BHL 4181a) that tells the same story, as well as annotated English translations of

On the Relations between Driving Patterns, Exhaust Emissions and Network Characteristics in Urban Driving

Popular Abstract in Swedish Bakgrund Hur gatunätet ser ut och planera's i städer påverkar förutom trafikarbetet även hur bilister kör. Körbeteendet i form av körmönster, d.v.'s. hastighet's- och accelerationsprofiler, påverkar i sin tur såväl bränsleförbrukning som avgasemissionsfaktorer. En betydande del av trafiken sker inom tätorter där såväl luftkvalitet som totala utsläpp är av betydelse. Äv

Female responses to male coos in the collared dove Streptopelia decaocto

Birdsong is one of the main models in sexual selection studies. Most investigations focused on oscines in which male song and female preference learning occur. Yet, some non-oscines are well suited for such studies as well. In Columbidae song learning does not occur. However, like in oscines, song is involved in inter- and intra-sexual interactions. Surprisingly, experimental evidence of female so